摘要:

Summary1. The spontaneous change in the number of circulating eosinophils from 8 to 12 o'clock was investigated in full‐term and premature infants 0–7 days old and in full‐term infants 30–120 daye old. This change is sometimes considerable. — 2. The change in the number of eosinophil leukocytes from 8 to 12 o'clock after the injection of small doses of ACTH (1/3and2/3mg per kilogram bodyweight) was investigated in the same groups of children. — 3. When the mean values of the change expressed in per cent of the number of eosinophils at 8 o'clock are considered, a decrease after administration of ACTH is found in all groups. A statistical analysis shows that no significant difference in the degree of this decrease exists between premature and full‐term newborns (0–7 days old). Nor is it possible to find such a difference between full term, 0–7 days old infants and infants 30–120 days old. — 4. The degree of response in the premature could not be correlated to weight or age of the infant. — 5. Cortisone had no significant effect on the number of eosinophils, when tested in the same way as ACTH. — 6. The results are discussed and it is pointed out that, if it is assumed that the eosinophil response to ACTH is a test of adreno‐cortical function, the data collected in this investigation are difficult to coordinate with the hypothesis, that there exists in the newborn a physiological trans

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17048.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryThe pyruvic acid concentration was estimated in blood from 20 children between the ages of 2 months and 13 years suffering from convulsive fits or petit mal. 25 patients between the ages of 6 weeks and 14 years with no tendency to convulsive fits or petit mal served as controls. A mean value of 1.43 mg per cent was found in the convulsive‐petit mal group (extremes 0.86 and 2.08 mg per cent), while in the control group the mean value was 1.30 mg per cent (extremes 0.83 and 2.07).In the patients over 5 years of age, who generally kept quiet during the sampling, normal mean values were found both in the convulsive‐petit mal group and the control group. Those under 5 years of age, who never were at rest during the sampling, presented abnormally high mean values in both groups. The high pyruvic acid values are probably attributable to the great muscular activity displayed by these infants during the venepuncture. Experiments were made which showed that in children even light muscular work produces a rather considerable rise in the pyruvic acid concentration in blood. The conclusion is drawn that no significant difference is found between children with convulsive fits or petit mal and a control series with regard to the pyruvic acid concentration in bl

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17049.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryA firm biological foundation for the beneficial effect of carbon‐arc light treatment is still lacking. Based on the assumption of a protective effect against infection, the investigations reported in this paper concern the production of antibodies in children during treatment with universal carbon‐arc light. Parallel control groups, treated with light of an indifferent ultraviolet content or with no light at all, were used in the studies. The formation of tetanus antitoxin after immunization with the usual doses of tetanus prophylactic could not be shown to be influenced by carbon‐arc light treatment. Neither was it possible to influence the tuberculin sensitivity of naturally positive persons, nor the development of local lesions and tuberculin allergy after vaccination with BCG. Attention is drawn to investigations concerning the neuro‐muscular system, physical capacity, and metabolic variations, as possibly being fruitful spheres for continued study, and strong emphasis is laid on the absolute necessity of accurate dosimetry in future scientific investigations concerning the biological effect o

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17050.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

Summary1. A study of the cells in the spinal fluid, as well as Nonne and Pandy reactions, was made in 211 cases of infantile diarrhea of various degree of severity. — 2. The number of cells in C. S. F. was invariably (2–4 examinations) below 5 per cmm in 100 cases, and it was found to be increased at least once as follows: 6–10/cmm in 30 cases, 11–20/cmm in 35, 21–50/cmm in 29, 51–100/cmm in 7, and over 100/cmm in 11 cases. The changes were generally more extensive in the severe cases, but the difference between them and the mildest cases which did not exhibit any symptoms pertaining to the central nervous system, was not particularly significant. — The majority of the cells were diagnosed as lymphocytes. — 3. If the protein reactions are also taken into consideration, the spinal fluid was found within normal limits in only 13 patients. — 4. The age at onset, the weight of the infant as compared with the expected weight, the alkali reserve on admission and other simultaneous infections do not seem to have any noteworthy effect on changes in the spinal fluid. — 5. Changes were found to be more frequent in diarrhea produced by the Shigellas (35 cases) than in other cases due to an unknown causative agent. — 6. Bacterial staining and culture of the C. S. F. were

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17051.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryIn a series of 1836 consecutive cases of infants with a birth weight of 3000 g or more, who had not shown any manifest defects during the first week of life and who after discharge with their mothers to their homes could be followed at least to the age of two months, the duration of breast feeding was compared with the amount of milk produced by the mother on the infant's sixth day of life. Duration of breast feeding was reckoned as the total time until the infant was definitely weaned from the breast. Those infants where the mother had delivered 200 ml of milk or less on the sixth day suffered considerably shorter periods of breast feeding than the rest, 44.1 per cent being weaned before 2 months of age against 6.6–0.6 per cent in the other groups, and only 22.1 per cent being breast fed for at least 6 months, as against 50–80 per cent in the groups with higher initial lactation. Those infants where the mother had been able to pump out at least 100 ml of milk beyond what the infant had sucked itself, were breast fed for a considerably longer time than the mean of the total series, and this applies to the group where the infant had been able to suck itself at least 300 ml as well as to the group where the infant had sucked not more than 200 ml. It seems, therefore, as if it would be possible to improve the prognosis of breast feeding in many cases by regular manual emptying of the brea

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17052.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryIn a material comprising 66 cases of premature infants, a regular examination of the fundi was carried out each week from birth. Amongst these cases there were 18 that presented a fundus picture similar to that described as being typical for early retrolental fibroplasia. These changes were reversible in all cases. Minor changes taking the form of a yellow‐white oolour and a slight oedema in the periphery of the. fundus were observed in 2/3rds of the total material. If one considers the time at which these changes were first manifest in relation to birth, it would appear that the greater the birth weight the sooner changes become apparent. When one considers the above and the high incidence of these minor fundal changes it is suggested that the changes described in this paper and in the early stages of retrolental fibroplasia are merely normal stages of developmen

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17053.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryThe author describes a case of lupus erythematosus, disseminatus in a girl aged 11 years. ACTH in doses of 24 mg daily for 12 days produced marked improvement which, however, lasted only as long a.8 the course of treatment was in progress.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17054.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17055.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryA case is reported of a child with fibrosis of the pancreas presenting a picture which resembled that earlier described in the disease designated acrodermatitis enteropathica and the possibility is suggested that this latter disease is always due to pancreatic fibrosis. The previously reported cases seem to support this assumption. The patient was treated with cortisone with very good effect. A preliminary account of the use of cortisone therapy for celiac disease is also given. The results noted appear to be encouraging.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17056.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17057.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY