摘要:

SummaryThe behaviour of intravenously injected radioiron in the plasma and its subsequent appearance in newly formed red cells was investigated in 25 infants aged between 0 and 273 days and in two children aged 591 and 931 days.The data are discussed in relation to previous studies concerning the change in red‐cell production that occurs during this period of life. The data indicate a rapid and profound fall in red‐cell production during the first few days after birth, and a very slow rate of haemoglobin synthesis during the following two months. Subsequently the data indicate an increased rate of red‐cell production.The data obtained during the first two weeks of life have also been analysed in terms of a recently proposed model for ferro‐erythro‐kinetics. The results indicate that the haemoglobin synthesis decreases at a very rapid rate (factor of 15–20) during the first 10 days of life. The absolute amount of haemoglobin synthesis at birth is between 2–3 % per day of the total circulating hae

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04305.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryThe activities of lipase, esterase, and alkaline phosphatase in breast milk were studied in relation to dietary fat supplementation.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04306.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryFour hundred and sixty‐seven patients 9–17 years old in an institution for mentally deficient children have been examined for external signs of puberty. It was found that the majority of these children mature at the normal time. Late maturing is also frequent and is usually associated with mental defect of genetic and prenatal origin.Early maturing and precocious puberty occurred only in children with brain damage dating from birth or later. These patients as a group also matured significantly earlier than children with mental defects from genetic and prenatal origin. Menstruation proved to be less reliable as a sign of maturation in institutionalized mentally defecti

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04307.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryThe urinary excretion of pyruvic acid and lactic acid per kg of body weight was observed to be higher in premature than in full‐term newborn infants. Mild toxemia of the mother did not influence the urinary pyruvic acid content in the child. Both the pyruvic and the lactic acid values in urine were equally high in the two age groups of premature infants, aged 1–9 days and 10–30

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04308.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryMembrane thickness and associated histologic pulmonary changes were studied in an autopsy series of 117 neonatal deaths presenting pulmonary hyaline membranes. The ages ranged from 6 hours to 7 days. The thickness of the membranes increased with postnatal age, generally reaching a maximum on the third to fourth day. Intra‐alveolar edema was prominent, especially during the first day, and diminished gradually. There was an increasing incidence of complications with age in the form of inflammation and intra‐alveolar hemorrh

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04309.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryThe red cell triiodothyronine uptake was performed in a group of 25 mongoloid children, in order to assess the applicability of this method in evaluating the thyroid status in mongolism. Our studies indicate that the mean T3uptake in mongoloids is increased. However in 11 out of 25 mongoloids studied by us the uptake values fall within the normal range, so that the test cannot be considered characteristic in mongolism. In all the mongoloid children the BMR was normal. On the contrary, in seven cases with an increased red cell T3uptake, a decrease of total serum protein and albumin was found. Since it is known that abnormalities of plasma proteins influence the red cell T3uptake, the hypothesis that some plasma factor(s) is responsible for the increased uptake of labelled triiodothyronine in mongolism is suggested. Whatever the extrathyroid factor(s) responsible for the increased red cell T3uptake is, the technique is not a valuable tool in assessing the thyroid function in mongolism.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04310.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryThis is a study of two families having an inherited nephropathy, manifesting itself in childhood by haematuria and in some cases albuminuria with or without hearing loss–a disease which has previously been described as Alport's syndrome.The first family comprises 22 descendants over three generations of a woman who has probably had hereditary nephropathy. Eight members had the renal disease. Two males had died in uraemia. The mode of inheritance was typically sex‐linked dominant. There was no case of hearing loss. The second family comprised three generations. Among 23 descendants of a woman having hereditary nephropathy and hearing loss there were 11 cases of hereditary nephropathy and two cases of hearing loss. The inheritance was dominant. Sex‐linked inheritance was possible.Especially in children the disease is apt to be misdiagnosed as acute glomerulo‐nephritis. As the symptoms are mild in females, a special search has to be made for the h

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04311.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryThe incidence of infantile hydrocephalus in Sweden was investigated in two separate studies; the number of cases present at birth was determined in a material from an obstetric clinic; the number of cases with an onset during the first year of life was penetrated in a field study.Among all 43,548 infants delivered at the Obstetric Department of the University Hospital of Uppsala in 1944‐61, malformations of the central nervous system were revealed in 48 cases, i.e. 1.10 per 1000 births. The corresponding figure for hydrocephalic births was 0.78. Hydrocephalus was combined withspina bifida cysticain 0.50 per 1000 births and in 0.49 per 1000 live births, while the corresponding figure for simple hydrocephalus was found to be 0.28 and 0.19 respectively.In the field study made in 1961 and comprising all children born in 1952‐57 in three different Swedish counties a total number of 72 cases with infantile hydrocephalus starting before one year of age was found among 64,630 live births. “Simple” hydrocephalus was present in 55 cases, i.e. 0.85 per 1000 live births. Incomplete information was obtained in this study about the incidence of hydrocephalus in cases withspina bifida cystica.The total incidence per year of new hydrocephalic cases with an onset before one year of age was obtained by adding the frequency figure for hydrocephalus withspina bifida cysticaat birth to the frequency figure for “simple” hydrocephalus starting during the first year of life. With this approximation a total incidence of 1.34 per 1000 live births was found, i.e. 22 cases per 1,000,000 in‐habitants, or 14 cases of “simple” hydro‐cephalus and 8 cases combined withspina bifida cystica.The reliability of the frequency figures obtained was checked for “simple” hydrocephalus from experience in practical clinical work during one year, 1961/62, and a g

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04312.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

摘要:

SummaryTwo cases of spontaneous neonatal rupture of the stomach are reported. In both instances the diagnosis was made pre–operatively. One infant died shortly after surgery. The other recovered. Causes of neonatal gastric perforation are discussed. The clinical picture and methods of diagnosis are briefly described. The necessity of early diagnosis and prompt surgery is emphasize

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04313.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1963.tb04314.x

出版商:Blackwell Publishing Ltd    

年代:1963

数据来源: WILEY