ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03699.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

SUMMARYIn order to find out the cause of the malignant gastroenteritis in infants, the stools from such children have been submitted to thorough bacteriological and serological examination.In a good many cases, furthermore, autopsy was performed under sterile precautions.As the bacteriological findings were not suggestive of any bacterial cause, attempts were made to isolate a possibly present virus. These attempts also proved negative.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03700.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

SUMMARYThe object of the present study is a case of purpura fulminans in a boy of 5, treated at the Stockholm Hospital for infectious Diseases. The patient, previously healthy, was taken ill with a fairly mild, although drawn‐out scarlatina infection, which judging from the high sedimentation rate had not healed when after the lapse of 9 weeks erythema exsudativum multiforme supervened and after another week large subcutaneous hemorrhages suddenly appeared, with increasing anemia and deterioration of the general condition leading to death in 3 days, notwithstanding vigorous therapy with inter alia large transfusions. Bleeding, coagulation and prothrombin times were maximally prolonged. The platelet count was not decreased. No bacteria were demonstrable in blood or internal organs but necropsy findings indicated sepsis. In connection with this case a survey was done of the purpura material of the Stockholm Hospital for infectious Diseases from the last 25 years, revealing that no previous case of purpura fulminans had occurred. Six of the purpura cases, all of them mild, were more or less associated with scarlatina and are described in detail. Furthermore, a brief description based on studies in the literature of purpura fulminans is presented, including its relationship to scarlatina, and purpura conditions in general in association with scarlatina. Purpura fulminans stands out as a rare but entirely typical disease, dominated by immense extravasations, with usually a rapid fatal course, generally in association with scarlatina or some other infectious disease. Therapy has in the majority of the cases been hopeless. The etiology is probably toxic‐allergic, with bacteria or bacterial toxins as causative agents, and there is rather a distinction of degree than of form, from the milder purpura Schonlein‐Henoch. A septic pathogenesis may also in a number of instances be considered. Finally, a brief epicrisis of the cases described is pres

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03701.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

SUMMARYIn order to ascertain the significance of the civil status and age of mother as well as the sex, birth number and birth weight of the child, for her lactation ability the author has made examinations on a material of 4 084 infants at the Stockholm Child Welfare Centres as to what degree the duration of the period of lactation varies with the factors mentioned. Consideration has herewith been taken, on the one hand to the period during which the mother has given the breast only (b) and on the other hand to the period during which she has given the breast at all (b + m). The results are as follows.As was to be expected, the unmarried mothers has, in spite of supervision, a shorter b and b + m than the married mothers, which must in the first place be ascribed to the circumstance that the unmarried mothers to a greater extent, have employment away from home.The sex of the child could not be proved to have any noteworthy influence either on b or b + m. The same applies to birth weight although in this case the weight class under 2 500 gr probably occupies an exceptional position.It has formerly been pointed out in literature that the older mothers give their children the breast for a longer period than the younger mothers. A closer analysis of the causes appears not to have been undertaken. The reason for this must partly be that the older mothers are to a greater extent pluripara; as unipara have a shorter b and b + m than pluripara independent of the age of the mother and the weight of the child at birth. But this is not the only cause, as the difference also appears in unipara at least as regards b + m. When it is a question of b only there rules however the reverse condition, here the younger mothers have a longer suckling time throughout. Therefore another cause of the longer total lactation period (b + m) in the older mothers might be sought in the circumstance that the older mothers compensate for their inferior ability to give the breast only by protracting the period of mixed feeding. The view finds support in the correlation calculations made with reference to b and m within the material. The differences in these respects, between the older and the younger mothers in the material are small all round, and smaller than was to be expected by reason of the information given in literature; this surely stands in connection with the fact that the feeding within the material here described is controlled.Since the mortality among the infants of Stockholm that are not controlled at the Child Welfare Centres appears to be at least twice as great as the mortality among the children of corresponding age that are controlled at the Child Welfare Centres evidence is given of the importance of tracing and supervising the uncontrolled children.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03702.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03703.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

SUMMARYLethal hereditary bullous epidermolysisis set up as one of the affections in the group of epidermolyses parallel with simple and dystrophic epidermolysis. It is characterized by bulla formation and epidermolysis with subsequent healing without cicatrization, with frequent bone dystrophy and ungual changes, rapid lethal issue, and familial occurrence. A typical case is described and illustrated. Already at birth the patient presents large epidermolyses. There is found bulla formation beginning with edema and cell infiltration in the uppermost layer of corium. The epidermis is exfoliated and replaced by a new thin atrophic epidermis, with corresponding imperfect development of sebaceous glands and elastic fibers. Hairs and sebaceous glands are atrophic everywhere and, after exfoliation of the epidermis, in further decomposition.In contradistinction to some previously reported findings, milliary cysts form from sebaceous glands. Cultivation from bullae yields no growth. The affection is resistant to any treatment applied. New bullae continue to appear, and after seven months the child dies without signs of infection. Pig. 1 shows the macroscopical look of the affection, whereas Pig. 3 illustrates the typical microscopical changes in the skin.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03704.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

摘要:

SUMMARYA girl of nearly two years old had a tumor in the right renal region, which after the findings at operation and the result of the histological examination provisionally was regarded to be a sarcoma. An unfavourable prognosis was given. However, five years later the general condition of the girl was excellent and no tumor could be felt in the abdomen. This gave reason to reexamine the old slides and it appeared necessary to modify the former diagnosis in that of sympathoblastoma. The prognosis of this sympathoblastoma is discussed, in consideration also of a number of publications on this subject. The conclusion is drawn that this prognosis need not be absolutely unfavourable.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03705.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1947.tb03706.x

出版商:Blackwell Publishing Ltd    

年代:1947

数据来源: WILEY