摘要:

SummaryA renal function test with creatinine tolerance determination has been employed in accordance with a method described by SUNDAL. The method seems to be a simple and reliable method, easily managed, and shows good correspondence with other renal function tests.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04008.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryThe authors review 214 consecutive encephalograms from children mostly suffering from epilepsy, oligophrenia, cerebral palsy, or various combinations of these symptoms. Sixty‐two patients had normal encephalograms, while almost all the others had more or less pronounced brain atrophy. Except in the cases with one‐sided symptoms, no conspicuous correlation existed between the nature of the symptoms or the electroencephalograms, and the character of the brain atrophy, except that most epileptics had normal pictures. Very often there was a disproportion between the severity of the clinical symptoms and the degree of brain atrophy visible on the encephalogram. In 60 per cent of the patients with hemiplegia or jacksonian seizures asymmetrical atrophy of the brain was founded. Agenesia of the corpus callosum was found in two cases. That no disease which could be treated neurosurgically was found in this series is, at least partially, accounted for by our practice of immediate transfer to the neurosurgical department of all cases suspected of brain tum

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04009.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

RésuméLes sérums de 8 enfants atteints de néphrose lipoïdique pure et d'un enfant présentant une néphrose lipoïdique compliquée d'atteinte rénale ont été examinés par la microélectrophorèse sur papier (Procédé de GRASSMANN et HANNIG: appareil Elphor‐H). Les avantages et les désavantages de cette microméthode, comparés à ceux de la macro‐électrophorèse d'après TISELIUS sont discutés. Chez tous les malades, atteints de néphrose lipoïdique, le taux de l'albumine est très bas; celui de la globuline α2toujours très élevé; la valeur absolue de la globuline γ est toujours tres basse. Les valeurs relatives de la globuline α1sont un peu au‐dessus de la normale. Les résultats obtenus pour la globuline β dépendent de la méthode employée; les valeurs sont plus élevées avec les méthodes réfractométriques qu'avec l'appareil Elphor. Avec la méthode optique, l'indice de réfraction de la globuline β est fortement influencé par les lipides. Les pourcentages et les valeurs absolues des différentes fractions varient sensiblement de malade à malade. II n'y a pas de concordance nette entre la répartition des différentes protéines dans la néphrose lipoïdique et les états d'œdème. On ne peut trouver de relation entre les valeurs rela

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04010.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryIn two cases with osteopetrosis the bone tissue has been studied by biophysical methods. The ultrastructure has been studied with X‐ray diffraction and the distribution of mineral salts with microradiography: the molecular structure is the same as in normal bone. The distribution of the mineral salts is quite different from normal bones, but shows characteristic patterns. The arrangement of collagen has been investigated in polarized light, the arrangement being quite irregular, a fact which seems to give a satisfactory explanation for the fragility of the bones. The cause of the disease is to be found in some functional anomaly of the bone‐forming ce

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04011.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryA preliminary report is given on investigations into the duration of sensitivity to tuberculin of 217 BCG vaccinated inmates of closed institutions. Both the inmates and the staff were under strict observation for tuberculosis. The results obtained are as follows:1. The isolated milieu has been effective in excluding the risk of tuberculous infection. No increased allergy suggestive of super‐infection was observed.2. The patients examined were vaccinated with BCG vaccine from the Bacteriological Laboratory of Sahlgrenska Sjukhuset, Gothenburg. 0.1 ml containing 0.05 mg of BCG organisms was injected intracutaneously into the left thigh. 96.4 per cent of those vaccinated were positive at the check‐up.3. The tuberculin reaction has been taken as negative if smaller than 10×10 mm 72 hours after the injection of 1.0 mg Mantoux.4. Two cases in which Koch's phenomenon was observed were excluded from the material.5. After 1 year 7.3 per cent had become negative, after 2 years 16.0 per cent, after 21/2years 28.3 per cent and after 31/2years 29.4 per cent.6. Mantoux test 0.01, 0.1 and 1.0 mg on the vaccinated showed that allergy to tuberculin, on the whole, declined with time, which supports the above re

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04012.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryParke‐Davis' palatable Chloromycetin palmitate was tested. It is easily taken by young children, in contrast to the extremely repulsive crystalline Chloromycetin (chloramphenicol). The absorption rate for Chloromycetin palmitate is slower than that for crystalline Chloromycetin and the maximum blood concentration, which for crystalline Chloromycetin is obtained about 2 hours after the fasting administration, is not reached until 1 hour later for Chloromycetin palmitate. A further retardation of absorption takes place if the drug is not administered fasting. The maximum blood concentration of crystalline Chloromycetin is three times higher than the maximum values for the palmitate of the same dosage. Control experiments show that the Chloromycetin palmitate dosage should be three times greater than that of crystalline Chloromycetin in order to obtain the same maximum blood concentrations. For the maintenance of a lowest blood concentration of Chloromycetin of about 5 γ/ml, a Chloromycetin palmitate dose of 200 mg/kg per 24 hours, administered in 4 doses, is required. In order to obtain a more rapid initial rise of the blood concentration the first dose of Chloromycetin palmitate should be given with a single dose of crystalline Chloromycetin (approx. 15 mg/k

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04013.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

Summary and ConclusionsThirty‐seven alimentary iron balances on 19 infants between the ages of 15 days and 9 months show that these subjects ingest an average of 0.37 mg of iron per day per kg, of which they retain an average of 0.19 mg, i.e. 53%. Within the limits of the amounts used in these experiments, the retention was shown to be approximately proportional to the intake. Within the age limits, we have observed only 2 zero balances and no negative on

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04014.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryFourteen iron balances in 7 infants from 4 to 71/2months show no influence of vitamin C on the intestinal absorption of dietary iron and of small doses of ferriccitrate.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04015.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryFour fatal cases of congenital valvular formation of the posterior urethra in boys are reported, two of which presented greatly dilated urinary tract at birth, and simultaneously cryptorchism.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04016.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SummaryA case of chronic acidosis diagnosed at the age of 4 months and followed for 2 years is discussed. The biochemical changes in the blood and urine were similar to those described in idiopathic renal acidosis. Calcifications in the renal parenchyma were first demonstrated by roentgen examination at the age of 2 years. There was no etiological explanation for the patient's condition which, being apparent from the first months of life, appeared to be congenital. Alkali treatment had a beneficial effect on the symptomatology but no curative effect upon the acidosis.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1954.tb04017.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY