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1. |
PLACENTAL TRANSFUSION IN THE PREMATURE INFANT WITH OBSERVATION ON CLINICAL COURSE AND OUTCOME |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 561-566
A. C. YAO,
J. LIND,
R. TIISALA,
K. MICHELSSON,
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摘要:
SummaryBlood volume was measured in 73 truly premature and 10 “small for date” term infants following early or late cord clamping at birth. Forty‐five normal full term infants from a previous study were included for comparison. The results demonstrated that placental transfusion occurred if cord clamping was delayed. The amount of placental transfusion in terms of red cell volume per kg b.w. in the premature infants under 2001 g was less compared to that of both normal full term infants and premature infants above 2001 g. The clinical course showed high incidence and mortality from respiratory distress in premature infants under 2001 g. An interesting observation was the apparently higher mortality resulting from idiopathic respiratory distress syndrome in the late‐clamped group weighing under
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04762.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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2. |
I. The Development of the Hering‐Breuer Inflation Reflex |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 567-571
GÖRAN BODEGÄRD,
GÖSTA H. SCHWIELER,
STEN SKOGLUND,
ROLF ZETTERSTRÖM,
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摘要:
SummaryThe Hering‐Breuer inflation reflex has been studied in babies of varying postmenstrual ages. The strength of the reflex was assessed by relating the relative increase of the length of the breathing cycle to the transpulmonary pressure when the airway was occluded.The Hering‐Breuer inflation reflex was found to be very weak at a postmenstrual age of 32 weeks. It was then found to increase to a maximum strength at a postmenstrual age of 36 to 38 weeks. Later on there was a decline of the strength of the reflex.The significance of the findings in relation to the frequent occurrence of periodic and irregular respiratory rhythm in infants of low gestational age has been discus
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04763.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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3. |
APPARENT RESPONSE OF IMPAIRED MENTAL DEVELOPMENT, MINOR MOTOR EPILEPSY AND ATAXIA TO PYRIDOXINE |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 572-576
H. EKELUND,
I. GAMSTORP,
W. VON STUDNITZ,
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摘要:
SummaryImpaired mental development, minor motor epilepsy, and ataxia in a 21/:!year old boy without cystathioninuria and with a normal reaction to the tryptophane‐loading test responded favourably to pyridoxine. Transient taurinuria and a long lasting general aminoaciduria occurred during the treatment. Certain clinical and biochemical findings and observations suggested that the child's symptoms were due to an increased pyridoxine requiremen
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04764.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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4. |
THE FOETAL DEVELOPMENT OF SERUM LEVELS OF IgG AND IgM |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 577-583
TORSTEN BERG,
BO A. NILSSON,
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摘要:
SummaryThe serum concentrations of the immunoglobulins G and M were studied in non‐viable foetuses with gestational ages of 13–26 weeks, and also in premature, mature and postmature infants. Among the prematurely born infants there was an overrepresentation of infants with very low gestational ages. The serum IgG concentrations in the mothers at the time of abortion or delivery were also studied.In full‐term infants there was a systematic difference between simultaneously taken capillary and umbilical cord samples, with higher serum concentrations of IgG in the former. For this reason umbilical cord sera were used throughout in this study.The maternal serum concentration of IgG was found to be of some importance for the foetal IgG level. The foetal: maternal IgG ratio increased, as also did the foetal IgG concentration, exponentially during pregnancy, with the exception of its last weeks when the development took place relatively more slowly. IgM in serum was observed (>1 mg/100 ml) in two foetuses with gestational ages as short as 14 and 16 weeks. From the 24th week of pregnancy onwards, IgM was found in the serum in practically all cases. From about the 29th‐30th week of pregnancy, no significant increase in the serum IgM with increasing gestational age was observed in the infants
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04765.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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5. |
A PATIENT WITH A DEFICIENCY OF SERUM‐CARNOSINASE ACTIVITY |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 584-592
P. J. HEESWIJK,
J. M. F. TRIJBELS,
E. D. A. M. SCHRETLEN,
P. J. J. MUNSTER,
L. A. H. MONNENS,
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摘要:
SummaryA patient with severe mental retardation, generalized convulsions and electro‐encephalo‐graphic abnormalities has been described. A marked carnosinuria was observed on a regular diet as well as on a diet which was essentially free of carnosine. No carnosine was found in plasma of this patient on any occasion. The serum‐carnosinase activity was extremely diminished compared to control subjects. Oral loading with L‐carnosine resulted in a much greater excretion of the administered L‐carnosine compared to a control subject. The consanguineous parents of the patient also excreted large amounts of the dipeptide and had decreased serum‐carnosinase activities. Infusion with freshly prepared donor plasma, containing active carnosinase, resulted in a temporary elevation of the enzymic activity in serum and a decrease of carnosine excreti
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04766.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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6. |
THERAPEUTIC STUDIES IN OSTEOPETROSIS |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 593-600
PETER JOHAN MOE,
ARNLAUG SKJæVELAND,
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摘要:
SummaryFour cases of osteopetrosis, with manifestations within the first months of life, are presented. The first two cases were siblings. One of them received no therapy, the other 12 blood transfusions and antibiotics. Therapy had no influence on the thrombocytopenia and haemolytic process in Case 2, and he developed rachitic‐like changes and a decrease in serum calcium during hospitalization. Both these two siblings died at the age of 5 months. The last two cases have been on prednisone therapy for 21 and 14 months, respectively. Case 3 is now doing well on prednisone, 7.5–10 mg every other day. Her mental and stato‐motoric development has so far been normal. Optic nerve decompression was performed in March 1968, and the eye on which the operation was performed still retains some vision. Case 4 was started on steroids when he was about 3 months older than Case 3. Splenectomy had to be performed due to high prednisone requirements, and he still needs prednisone, 15 mg every other day. He seems, unfortunately, to be blind and slightly retarded. Heparin seems to be of no practical value in this disorder. Cellulose phosphate therapy resulted in impaired calcium absorption. The resulting hypocalcemia seems, however, to have very little, if any, effect on the underlying di
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04767.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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7. |
5‐HYDROXYINDOLEACETIC ACID IN CEREBROSPINAL FLUID OF HYDROCEPHALIC CHILDREN |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 601-608
H. ANDERSSON,
B.‐E. ROOS,
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摘要:
SummaryThere was a significant increase in the level of 5‐HIAA in lumbar CSF of children with hydrocephalus compared with “non‐hydroce‐phalic” children. In “non‐hydrocephalic” children the values of 5‐HIAA were found to be highest in the newborn successively decreasing to the levels of adult persons at the age of about one year. Prematurely born children seemed to have relatively higher levels of 5‐HIAA in CSF compared with full‐term children. Adult persons were not included in the study.The ventriculo‐lumbar ratio in different types of hydrocephalus was calculated. A diminished level of 5‐HIAA was measured after surgery with a functioning shunt. All the findings support the theory that the cause of the increased level of 5‐HIAA is a decreased elimination of the acid metabolite from CSF. Determination of 5‐HIAA in CSF might be a simple and useful diagnostic complement in various neurological diseases, where the suspicio
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04768.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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8. |
DOWN'S SYNDROME TRANSMITTED THROUGH MATERNAL MOSAICISM |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 609-614
DAGFINN AARSKOG,
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摘要:
SummaryTwo families are reported in which Down's syndrome was transmitted through phenotypi‐cally normal mosaic mothers. In the first family the mother had normal/G‐trisomy mosaic, and on two successive pregnancies at the age of 22 and 24 years she gave birth to two sibs with regular G2i‐trisomy and Down's syndrome. In the other family the mother had a mosaic of normal and balanced D/G21 translocation cells, and at the age of 32 years she gave birth to a child with D/G2ttranslocation trisomy and Down's syndrome.Mosaic mothers carry a considerable risk of having children with Down's syndrome. Exact prediction of the risk cannot be given since the extent of gonadal involvement in the mosaicism is un
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04769.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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9. |
HEMORRHAGIC MUCOSAL NECROSIS OF THE GASTROINTESTINAL TRACT IN THE NEWBORN |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 615-620
F. HANBERG SØRENSEN,
M. VETNER,
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摘要:
SummaryTwo cases of hemorrhagic mucosal necrosis in the gastrointestinal tract without vascular occlusion are reported. This combination does not seem to have been previously described. Both cases were observed in newborn infants and in both cases the condition was combined with intestinal perforation. Both infants died. Possible etiologic factors are discussed and the histological criteria reviewed.
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04770.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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10. |
ACUTE HEMIPLEGIA IN GLYCOGEN STORAGE DISEASE, TYPE 1 |
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Acta Pædiatrica,
Volume 58,
Issue 6,
1969,
Page 621-624
RICHARD N. FINE,
ROBERT PODOSIN,
GEORGE N. DONNELL,
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摘要:
SummaryA 21‐month‐old girl with GSD, Type 1 developed acute hemiplegia with homonymous hemianopsia following a prolonged hypoglycemic seizure. There was gradual improvement in motor function. However, the patient had subsequent episodes of transient blindness with and without seizure activity which were unrelated to hypoglycemia. Serial EEG findings suggested that the hemiplegia resulted from a vascular accident and led to neural dysfunction causing subsequent transient blindn
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1969.tb04771.x
出版商:Blackwell Publishing Ltd
年代:1969
数据来源: WILEY
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