摘要:

ABSTRACT:Landtman, B., Louhimo, I., Rapola, J. and Tuuteri, Leena. (The Children's Hospital, University of Helsinki, Helsinki, Finland.) Causes of death in transposition of the great arteries. A clinical and autopsy study of 140 cases. Acta Paediatr Scand, 64: 785, 1975.–The causes of death were assessed in 140 infants and children with transposition of the great arteries studied clinically and post mortem. Half of the children were under one month old. Death occurred during the first year of life in 118 cases. Balloon atrial septostomy and/or cardiac surgery were performed in 37 cases, and 7 patients died following operations for extracardiac malformations. Congestive heart failure was the most common single cause of death, occurring in 109 cases. All but 7 patients were cyanotic. Extracardiac malformations were encountered in 39 patients and were considered a main cause of death in 22 of these. Various infections, mostly pneumonia, occurred in half of the cases. Forty‐one patients had vascular accidents in various organs. These complications were more common in operated than in nonoperated cases. Miscellaneous causes of death, including hyaline membrane disease and/or pulmonary atelectases, occurred in 30 patients. The study illustrated the complex symptomatology and therapeutic problems presented by critically ill infants with transposition of the great arter

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03924.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Stubbe, P. and Prindull, G. (Department of Paediatrics, University of Goet‐tingen, D 34 Gottingen, Kinderklinik, BRD): Fanconi's anemia. II. Are multiple endocrine insufficiencies a substantial part of the disease? Acta Paediatr Scand, 64: 790, 1975. –Three children with Fanconi's anemia belonging to a family where 6 children had the disease were investigated. One child had growth hormone deficiency, a second child showed subnormal response of testosterone to gonadotropin stimulation and the third child had a missing insulin release following arginine. This report shows that growth hormone deficiency is not necessarily linked with Fanconi's anemia when it occurs in a family. Multiple endocrine insufficiencies do not appear to be part of the dise

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03925.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Sundelin, C. and Vuille, J.‐C. (Department of Paediatrics, University Hospital, Uppsala, Sweden and the Institute of Social and Preventive Medicine, University of Berne, Berne, Switzerland). Health screening of four‐year‐olds in a Swedish county I. Organization, methods and participation. Acta Paediatr Scand, 64: 795, 1975–Since January 1969, a systematic health screening has been offered to 4‐year‐olds resident in the county of Uppsala, Sweden, at the ordinary Child Health Centres by the regular staff. This report describes some organizational and methodological aspects and presents participation rates and reasons for non‐participation. From the overall experience it is concluded that the program is feasible with respect to systematic examinations and data collection, acceptance by the public and the staff, and with respect to the strain on existing resources. The reasons for and the importance of program changes are discussed, and the main advantages and drawbacks of the decentralized approach are mentioned. Finally, a theoretical framework for a quantitative evaluation of effectiveness

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03926.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Sundelin, C. and Vuille, J.‐C. (Department of Paediatrics, University Hospital, Uppsala, Sweden and the Institute of Social and Preventive Medicine, University of Berne, Berne, Switzerland). Health screening of four‐year‐olds in a Swedish county II. Effectiveness in detecting health problems. Acta Paediatr Scand, 64: 801, 1975.–Quantitative results obtained during the first 3 years of operation of a routine health screening program for 4‐year‐olds are presented. From these figures it is concluded that theeffectivenessin detecting previously unknown health problems needing treatment is high enough to justify the continuation of this systematic health screening by the ordinary child health staff. However, the total prevalence of newly detected anomalies was lower in our population than in similar studies where the screening was performed by a few teams of specially trained professionals. The consequences of this observation are briefl

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03927.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Gothefors, L., Oiling, S. and Winberg, J. (Departments of Paediatrics and Clinical Bacteriology, University of Umeå, Umeå, Sweden and Department of Immunology, Institute of Medical Microbiology, University of Goteborg, Goteborg, Sweden). Breast feeding and biological properties of faecalE. colistrains. Acta Paediatr Scand, 64: 807, 1975. —Human milk may contribute to protection against gram‐negative infection by promoting intraluminal agglutination or killing of bacteria or by preventing bacterial attachment to epithelial surfaces. This paper explores the effect of human milk on the sensitivity of faecalE. colito serum bactericidal activity and agglutination specificity, factors which have been regarded as related to virulence. FaecalE. coliisolated from breast‐fed infants differed from those from formula‐fed infants in two respects: They were more sensitive to the bactericidal effect of human serum and more often spontaneously agglutinating.E. colistrains isolated from sources outside the gastro‐intestinal tract, that is the prepuce and female peri‐urethral region, were in breast‐fed babies less sensitive than faecal strains. The findings are compatible with the hypothesis that a breast‐milk factor favours the proliferation of mutant strains. The observed effects of breast‐milk might be associated with decreased bacterial virulence, and be one of the ways in which breast‐feeding prote

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03928.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Carlsson, J. and Svenningsen, N. W. (Department of Paediatrics, University Hospital, Lund, Sweden). Respiratory insufficiency syndrome (RIS) in preterm infants with gestational age of 32 weeks and less. Neonatal management and follow‐up study. Acta Paediatr Scand, 64: 813, 1975.–The clinical entity of respiratory insufficiency syndrome (RIS), i.e. irregular breathing leading to recurrent apnea and bradycardia in an otherwise healthy preterm infant, has been studied in respect of symptomathology and management with intensive case including ventilatory support. During a 4‐year period 26 of 103 infants with gestational age 32 weeks and mean birth weight 1304 g (range 710 to 1830 g) developed RIS. In most infants the initial apnea occurred after 2 and before 72 hours post delivery but in some infants later. Because of progressive hypoxemia and acidosis IS of the 26 RIS infants required IPPV treatment. The 76 % survival rate of RIS infants seems to justify intensive care with ventilatory support even in the smallest preterm infants with RIS, especially as the follow‐up study performed at 15 months to 3 ½ years of age showed neurological sequelae in only 3 of 20 surviving babies, i.e. 15 % seque

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03929.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Christoffersen, J., Marner, T. and Raabo, E. (Department of Paediatrics, Glostrup Hospital, Glostrup, Denmark). LDH‐isoenzymes in children. A comparison of values from capillary and venous blood. Acta Paediatr Scand, 64: 822, 1975.–A comparison has been made of serum values of LDH‐isoenzymes obtained by simultaneous sampling of capillary and venous blood in 40 normal children. No satisfactory correlation between the paired values could be found. Evaluation of the pattern of serum LDH‐isoenzymes in children therefore requires a reference, i.e. normal values of isoenzymes obtained by the same technique of blood s

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03930.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Thomas, D. B. (Research Unit for the Newborn, Children's Medical Research Foundation, Royal Alexandra Hospital for Children, and The Women's Hospital, Crown Street, Sydney, Australia). Survival after massive pulmonary haemorrhage in the neonatal period. Acta Paediatr Scand, 64: 825, 1975.–4 babies with massive pulmonary haemorrhage were seen in an 18 month period. 2 had severe rhesus haemolytic disease, and the other 2 severe respiratory problems. There was evidence of a profound respiratory acidosis and hypoxia prior to the onset of the haemorrhage. 2 babies survived the episode and subsequently developed normally. Adequate ventilation and attendance to the treatment of blood coagulation disorders may have been a factor in their surviva

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03931.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Moe, P. J., Haneberg, B. and Finne, P. H. (Department of Paediatrics, University of Tromsø, Tromsø and Department of Paediatrics, University of Bergen, Bergen, Norway). Serum lysozyme activity in children with hematological and malignant disorders. Acta Paediatr Scand, 64: 830, 1975.–Pretreatment serum lysozyme activity was high in 2 children with myelomonocytic leukemia, 800 and 1000′/ig/ml, normal in all 10 cases of acute myelocytic leukemia and subnormal in 21 of 34 cases of acute lymphocytic leukemia. Normal values were found in all but one case of acute lymphocytic leukemia during complete remission including 8 cases after all therapy had been discontinued. All 8 are still in complete remission. Low serum lysozyme activity was found in 5 patients with acute lymphocytic leukemia in complete relapse, this could possibly be helpful in the diagnosis of early relapse. Activity was subnormal in 5 of 17 children with malignant tumours, and in 3 of 65 cases of various benign hematological diso

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03932.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

ABSTRACT:Henriksson, C., Andersen, H. J., Gustafsson Å. and Gelin, L.‐E. (Department of Surgery I, Sahlgren's Hospital, Gothenburg, Sweden, and Department of Pediatrics, Odense Hospital, Odense, Denmark). Renal transplantation in children. Acta Paediatr Scand, 64: 833, 1975.–From July 1967 to September 1974, 26 kidney transplantations were carried out in 16 children aged 6 to 17 years, in Gothenburg. The average age at the primary transplantation was 12 years and average body weight 29.7 kg. Five patients had familial juvenile nephronophthisis, 5 chronic glomerulonephritis, 5 chronic pyelonephritis, and one bilateral Wilms's tumour. Four patients were predialytic. Fourteen grafts came from living related donors. The surgical technique was standard as was the immunosuppression with azathioprine and cortisone; exceptionally antilymphocyte globulin was used. Thirteen patients were alive in September 1974, observed 2–65 months, 8 with a normal serum creatinine, 3 with moderately elevated serum creatinine, and 2 on hemodialysis. The 6‐ and 12‐month survivals of patients are 100% and 93% respectively. Normal growth and full rehabilitation in recipients of functioning grafts make renal transplantation justified as a therapeutic procedure in terminally uremi

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1975.tb03933.x

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY