摘要:

Summary1An account of the results of intravenous and intramuscular injections of whole blood, plasma and serum into premature infants is given. In all cases there is an increase of carbonic anhydrase activity in the infant's blood.2The cause for the increase in enzyme activity is discussed. This is found to be probably due to an activating factor in plasma; this factor is thermostable, dialysable and seemingly of non‐electrolyte character.3The possible inconveniences that premature infants could suffer on account of their low carbonic anhydrase activity and the help possibly afforded to these infants by transfusions are discusse

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17036.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryThe author has investigated the carbonic anhydrase activity in organs from fetuses and premature infants and shown that the activity in certain organs such as kidney aid stomach surpass that in the blood of fetuses of corresponding age. The significance of the enzyme activity in the fetal organs is discussed.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17037.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17038.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryA short review is given on the methods used in fat tolerance tests in children.The determination of the total fat in serum according to the turbidi‐metric method of Kunkeland Ahrensis very simple and may be used as a screening test when poor fat absorption is suspecte

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17039.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

Zusammenfassung1An Hand einer neuen Beobachtung von chronischer Aminoaci‐durie mit Cystinspeioherung, welche in typischer Weise ein blondhaariges I‐jahriges Madchen blutsverwandter Eltern betrifft, werden neue dia‐gnostische und klinische Befunde d'ieser seltenen Erkrankung zusam‐mengestellt.2Neben der alteren Methode des Cystinkristallnachweises im Sternal‐markausstrich vermag eine technisch einfache Darstellung des kristal‐linischen Cystins in der Augenbindehaut die Verdachtsdiagnose schnell zu sichern. Kristallographische Differenzierungen erlauben hierbei grund‐sätzlich 2 Kristallformationen zu unterscheiden, die durch Eigentüm‐lichkeiten der Lichtbrechung voneinander abweichen.3Chromatographische Aminosäurenbestimmungen werden mikro‐biologisch ermittelten AS‐Konzentrationen des Urins und den bislang wenig bekannten Serumwerten gegenübergestellt. Dabei lässt sich feststellen, dass neben wechselnden Konzentrationen anderer Aminosäuren weder im Serum noch im Urin eine Cystinvermehrung vorhanden ist.4Die Speicherung des schwerlöslichen Cystins im Retikulo‐endothelialen System kann durch den Nachweis von Verschiebungen der Serum‐eiweisskörper nach elektrophoretischer Bestimmung bekräftigt werden.5Bezüglich der Glykolabilität dieser Erkrankung werden neue mit dem Zuckerhaushalt gekoppelte Verschiebungen der Kaliumbilanz angeführt. Die Glukosenatur der, durch Anhäufung S‐haltiger Verbindungen im Blute der an Cystinose erkrankten Kinder, erklärbaren Ausscheidung reduzierender Substanzen wird durch chromatographische Differenzierungen sichergestellt.6Mit den kurz erwähnten pathogenetisch nahestehenden Zustands‐bildern wird vor allem eine Verwandtschaft der Aminoacidurie vom Cystinosetyp mit der Coeliakie hervorgehoben und

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17040.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryA caae of Niemann‐Pick's disease is reported in a boy of 5 months. He exhibited increased values of phospholipoids, cholesterol, and neutral fat in the serum. The same condition was previously reported in his elder brother, but does not appear to have occurred among more distant relatives. The parents are first cousin

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17041.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryAn examination of two sisters with psychogenic hyperorexia and anorexia respectively; and two brothers of another family with the same symptoms, make up the background of a discussion of the relations between anorexia and hyperorexia.In Family I anorexia in the younger girl seems to be the primary disturbanoe of appetite in the surroundings. The sister's hyperorexia should be regarded as a direct outcome of the younger sister's eating‐inhibition, an attempt to keep up the position at home that she felt threatened when the little one wm born. The adequacy of this mechanism appears from the predominant part that food plays in the house.In Family II there is no such connection between the symptoms of the two brothers. The younger suffers from anorexia, in this case a regressive mechanism, probably with a dyspepsia in babyhood as starting‐point. His brother has during his early years displayed various psychogenic symptoms — fits suggesting asthma, enuresis nocturna, several behaviour‐disturbances — and finally hyperorexia, which apparently is a link in the chain of symptoms. The family is dominated by a perfectionist mother. The reason why both children should react against these surroundings with disturbances of appetite does not appear from the examination.Two different kinds of psychical expression are found in these four children, partly a passive, non‐protesting type, partly an active, aggressive type. In one family the passive expression is combined with hyperorexia and the active one with anorexia; in the other family it is the other way round.The advantage of connecting anorexia with hyperorexia is emphasized. The introduction of the common termpsychogenic dysorexiais suggestad for the symptoms concerned, in order to call attention to the common source: disturb

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17042.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryA review of the clinical symptoms, particularly the skin lesions, of the various types of xanthomatosis is given. A case of juvenile xanthoma is then described. Characteristic of this type is that it usually appears within the first year of life and the skin lesions consist of small solitary tumours. The blood cholesterbl and the total blood fat are within normal limits. The internal organs are not usually involved and the prognosis is then good, but a few cases with later systemic lesions have been reported.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17043.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummarySince Albrightet al. (1942) reported the first three cases of a syndrome, which they called pseudo‐hypoparathyroidism, about fifteen cases have been described. Another case of pseudo‐hypoparathyroidism is described. The patient was a girl, aged 9, with short, thick‐set figure, round face, stubby hands with shortness of all metacarpals except those of index fingers, soft tissue calcifications, low IQ, hyperphosphatemia and hypocalcemia. She has an imbecile uncle with the same habitus. After administration of parathyroid extract there was no phosphate diuresis response and a small but insignificant increase of serum calcium levels. Dihydrotachysterol, however, kept the serum calcium on a level of the lowest limit of the normal v

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17044.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17045.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY