摘要:

SummaryA total of 98 fat balance studies varying from 3 to 7 days duration was made on 32 premature infants weighing at the beginning of the studies from 960 to 2 220 g. The fat content of diet varied from 2.6 to 7.8 g/kg/day and was supplied from breast milk, raw, frozen or heated at various temperatures for different intervals of time or from cow's milk, pasteurized, or subjected to heating at various temperatures for different periods. It is concluded that prematures retain breast milk fat to a remarkably high degree even though the breast milk has been frozen or subjected to various heat treatments. Premature infants do not retain fat from cow's milk as efficiently as they do human milk fat. The nature of the heat treatment of cow's milk did not influence the degree of retention.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17024.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17025.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryTwo case reports of ectodernial dysplasia in two females are presented. One case is believed to be the first reported with evidence of direct descent from mother to daughter. The other is a case of the mendelian dominant type. The submission is made that the anhydrotic type is not necessarily always a sex‐linked recessive manifestation in males but that both types, anhydrotic sex‐linked recessive, and dominant, may. occur in each sex although more frequently in the m

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17026.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryA study is made of 70 cases of severe infantile gastroenteritis; half of the patients were treated by subcutaneous administration of solutions containing potassium during the first few days of treatment, and the rest were given solutions free from potassium for a corresponding length of time. Therapy was similar in all other respects.Both groups are similar in regard to age, picture of the disease, duration prior to admission and alkali reserve at the begining of treatment.Of the 35 infants treated without potassium 15 died, compared with 7 in group treated with potassium. One of the former group had bronoho‐pneumonia discovered at autopsy. In the latter group one also had bronchopneumonia, one purulent meningitis, and another thrombosis of the sagittal sinus. If these cases, whose prognosis was obviously unaffected by the fluid therapy are excluded, the mortality rate of those treated without potassium was 41 per cent and for those treated with potassium 13 per cent. The recoveries belonging to the latter group showed on an average a more rapid gain in weight than patients treated without potassium.The advantage of potassium therapy is evidenced by the resul

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17027.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

Summary1The 22 Haemophilus influenzae strains that were tested were all sensitive to chloramphenicol.2With an oral dosage of about 100 mg chloramphenicol per kg per day about 20–60 times greater chloramphenicol content in the spinal fluid was obtained than the sensitivity of the strains cultured from Haemophilus influenzae meningitis cases.3Thirteen cases of Haemophilus influenzae meningitis, the average age of which was 15.4 months, the youngest child being 3 and the oldest one 47 months, have been treated as follows: 5 only with chloramphenicol; all recovered; 1 with chloramphenicol and streptomycin: recovered; 7 with streptomycin, penicillin, and sulpha drugs: of these 3 recovered, 3 died, and one recovered with sequelae.4The patients treated with chloramphenicol generally recovered more quickly than those treated with streptomycin and other drug

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17028.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryThe blood stream can be directly observed in the conjunctival blood vessels with the aid of a stereo‐microscope at 40–100 x magnification. When this method of observation was applied in a large number of newborn infants during the first days or weeks of life it was noted that the blood stream in the small vessels and capillaries of the conjunctiva was even and ungranulated in completely healthy children. The red cells flowed along in even, single or double lines in both capillaries and para‐Capillaries. In the larger vessels, the blood stream was even and ungranulated. However, as soon as even very slight prodromal signs of infection appeared, a slight rise in the temperature, a lowering of the general condition, vomiting or abnormality of the stools;for instance, the circulating red cells began to form into clumps. In many cases, aggregation of the red cells was the first sign of infection to appear. The aggregating tendency was more pronounced when the infection was severe than when it was mild. The aggregation phenomenon was characterized by the fact that, in capillaries and paracapillaries, colourless spaces were observable between erythrocyte “carriages” of varying lengths. In vessels of larger calibre the blood stream was granulated. The rate of flow was decreased in all the vessels studied. As it is known from earlier investigations that the degree of red cell aggregation bears a certain relationship to the increased sedimentation rate of the red cells, intravascular aggregation in infants with infection may be regarded as a sedimentation reaction directly observedin vivo. Instead of using the microsedimentation reaction an early diagnosis of infection can be made by direct observation of the blood stream with a view to detecting the possible presence of red cell aggregation. This also holds good for premature babies. Cases of erythroblastosis foetalis and cases with extensive traumatic lesions (e.g. parturition injuries) form exceptions to this rule since they also display intravascular red cell aggregation.Fifteen cases are

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17029.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryThe blood stream in the small conjunctival vessels was observed in twelve cases of erythroblastosis foetalis with the aid of a stereoscopic‐microscope immediately after birth. Intravascular red cell aggregation was observed in all the immunized infants. No aggregation was observed in healthy newborn infants. The correlation between the blood values in the child and the degree of aggregation was such that, when the aggregation was pronounced the red cell and hemoglobin values were low. After a blood exchange, or in connection with a spontaneous improvement in the state of health, the red cell aggregation decreased proportionally as the blood values improved.The diagnostic and clinical significance of these observations is discusse

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17030.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryAuthentic communications about re‐infections with measles are rare. The writer reports a case of presumably fourth infection with measles in an 8‐year‐old boy who had also had whooping cough and German measles twice, and, further, recurring tonsillitis and “influenzal infections”. The patient's mother, 2 of her sisters and brothers, and a brother had had measles twice, the brother also whooping cough twice.Examinations of the patient's serum proteins showed a normal content of total protein, albumin and globulin. The electrophoretic pattern was normal. Diphtheria and tetanus antitoxins could not be demonstrated in the patient's blood. Parotitis complement fixation<4. Antibody against influenza A could be demonstrated. After vaccination against diphtheria and tetanus a normal formation and excretion of antitoxins was ascertained (followed for a year). The electrophoretic pattern remained unchanged. Previous communications and the anamnestic information received about this patient seem, however, to indicate that there are individuals who have a poor immunization capacity against measles (in this patient also against certain other infections), and that this is a constitutional hereditary

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17031.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryReport of an 11/2year old boy with Hand‐Schüller‐Christian disease. A dose of 3 mg cortisone per kg of body weight per day, injected intramuscularly, initially resulted in conspicuous improvement. Thus, the general condition improved, the hepatomegaly and splenomegaly decreased, as did the protrusion of the eyeball, polyruia and polydipsia. Oedema subsequently developed and became increasingly severe; no changes were found in the blood chemistry to account for it. It was necessary to discontinue cortisone therapy after 3 weeks. The patient's condition deteriorated rapidly and he died after a further 5

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17032.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY

摘要:

SummaryThis paper describes a case of organic mercury poisoning in a child from a mercury‐intoxicated family. The condition has not hitherto been reported among children. The child was poisoned after eating porridge prepared from flour which had been treated with an dkyl mercury compound, panogen, which is used by farmers in seed dressing. The main clinical signs and symptoms are due to severe damage to brain tissue, and thus differ from the parenchymatous lesions resulting from inorganic mercury poisoning. Treatment with BAL was of doubtful valu

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1952.tb17033.x

出版商:Blackwell Publishing Ltd    

年代:1952

数据来源: WILEY