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1. |
Introduction |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 1-1
C.J.H. KELNAR,
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb11661.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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2. |
The Rosén von Rosenstein Award |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 3-5
Rolf Zetterström,
Olle Hernell,
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb11321.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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3. |
Is there an Auxological Basis for Growth‐Promoting Treatment with Human Growth Hormone in Short Children? |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 4-10
M.B. RANKE,
B. BLANK,
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb11623.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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4. |
Medulloblastoma in Nordic Children. I |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 5-11
N. CLAUSEN,
S. GARWICS,
A. GLOMSTEIN,
G. JONMUNDSSON,
S. KRUUS,
M. YSSING,
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摘要:
ABSTRACT.The average annual incidence of histologically verified medulloblastomas was 5.4×10‐6among all 4.9 million Nordic children younger than 15 years from 1968 to 1977. The ratio between boys and girls was 2:1. The incidence had no clear seasonal variation and it peaked at 3 to 4 years of age at onset. The rate of survival after 5 years was 17.4%, equal for boys and girls, but highest in the older age groups. Tumor growth accounted for most deaths with lack of local control in 88% of 112 children autopsied. Metastases outside of the central nervous system occurred in only 6 % of the children. Thus, intensification of the treatment should be directed towards the central nervous syst
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb17306.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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5. |
Introduction |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 6-9
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PDF (195KB)
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb17302.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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6. |
INTRODUCTION |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 7-7
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb17291.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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7. |
REVIEW OF THE LITERATURE |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 8-21
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb17292.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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8. |
Methods and material |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 10-27
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb17303.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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9. |
Endocrine Basis for Growth‐Promoting Therapy |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 11-13
K. ALBERTSSON‐WIKLAND,
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ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb11624.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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10. |
Medulloblastoma in Nordic Children. IINeurologic and Social Prognosis in Long Term Survivors |
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Acta Pædiatrica,
Volume 79,
Issue 1,
1990,
Page 12-19
M. YSSING,
S. GARWICZ,
A. GLOMSTEIN,
G. JONMUNDSSON,
S. KRUUS,
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摘要:
ABSTRACT.Forty‐four Nordic children surviving from histologically documented medulloblastoma diagnosed before the age of 15 years from 1968 to 1977 were studied by clinical investigations 5–15 years after the time of diagnosis. Thirty percent of the children suffered from major neurologic and/or intellectual late effects impairing their social life. The remaining 70 % of the children had mild or no motor, sensory, or mental dysfunction. In 30–35% of the patients the quality of life and the level of function in school and in professional life were impaired to a higher degree than was expected from the clinical observations. A favourable long term prognosis with regard to neurologic and intellectual function and to quality of life was significantly correlated to age>10 years at diagnosis, and it was insignificantly associated with biopsy as the only primary surgical intervention and with peri‐operative treatment with corticosteroids. Sex, length of diagnostic delay, and different treatment modalities did not influence the long term pr
ISSN:0803-5253
DOI:10.1111/j.1651-2227.1990.tb17307.x
出版商:Blackwell Publishing Ltd
年代:1990
数据来源: WILEY
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