摘要:

SummaryIn order to assess the significance of gastrointestinal protein loss as a cause of plasma protein hypercatabolism in patients with nephrotic syndrome, seven nephrotic children were studied simultaneously with radioiodine labelled albumin and a test substance,51,Fe‐labelled iron dextran, for evaluation of gastrointestinal protein loss.All the patients displayed a pronounced hypercatabolism of albumin, which could not be accounted for by urinary protein loss. A slightly increased gastrointestinal protein loss was demonstrated in 4 patients, whereas, in 3 patients, the faecal loss of macromolecules was within normal limits.The relation between protein catabolism and faecal loss of macromolecules was compared in the nephrotic children and in 20 patients with protein‐losing enteropathies. It is concluded that gastrointestinal protein loss is insignificant in the nephrotic syndrome, and unable to account for the marked endogenous hypercatabolism of albumin.Albumin synthesis was normal or somewhat increased. An abnormally high fraction of the total albumin mass was present in the intravascular space in 4 of the 7 child

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04692.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SummaryA double blind trial of prednisolone treatment was carried out on 95 children with clinical evidence of epidemic bronchiolitis. The trial showed that there was no difference between the prednisoIone and the placebo group in the duration of symptoms and signs.Eighty‐four per cent of children were shown to be infected with respiratory syncytial virus. Prednisolone in the dosage used did not affect the antibody response to infection.The presence of maternal antibody to respiratory syncytial virus, while not preventing infection, reduced the number of active antibody responses in children aged 3 months or younger.Eight children had a double infection with respiratory syncytial virus and adenovirus which lengthened their average stay in hospital by two days and the overall duration of illness by more than three day

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04693.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SummaryErythropoietin levels (ESF) were measured in premature infants with and without the respiratory distress syndrome in an effort to define the role of intrauterine hypoxia in the genesis of the disease. No difference in levels could be detected between infants with and without the: respiratory distress syndrome. This suggests that either intrauterine hypoxia plays no role in the genesis of the respiratory distress syndrome or that the hypoxia is (1) of short duration, (2) of relatively long duration, or (3) remote with respect to the time of birth. The higher levels found in full‐term infants suggested that hypoxia before birth is a more common feature of the term delivery than the premature deliver

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04694.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04695.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SummaryThe acid‐base and electrolyte balance was studied in 8 diabetic and 8 healthy mothers and their infants at caesarean section near term.Microliter methods were used for determination of pH, total CO2, potassium, sodium, chloride, calcium, total protein, inorganic phosphorus, glucose and lactate.The acid‐base and electrolyte balance of the newborn infant of a well‐controlled diabetic mother did not differ significantly from that of a newborn infant of a healthy mother.The infant of a diabetic mother seemed to be able to correct for an excess load of glucose and to maintain a “normal” level in the blood in the umbilical artery.Earlier observations that intense maternal hyperventilation is associated with a changed uterine and placental circulation and results in fetal acidosis were not confirmed in the pres

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04696.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04697.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SummarySecondary disaccharide intolerance was a feature of the gastroenteritis in all cases and lasted from 2‐10 weeks, necessitating treatment with a disaccharide‐free milk. No bacterial or viral pathogens were isolated from the 5 affected infants, and all infants in whom disaccharide intolerance was recognised, survived. Lactose tolerance tests in the recovery phase were helpful in deciding when to reintroduce a normal (lactose containing) m

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04698.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04699.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SummaryFour patients presenting a severe pneumonia due to adenovirus type 7 are reported. One of them died, and intranuclear inclusion bodies characteristic for the illness were found. In infants and small children, this infection might in addition give meningoencephalitic symptoms, hepatomegaly, vascular disorders and hemorrhagic tendency, as some of these patients demonstrated. Intravascular coagulation initiated by the virus infection could explain several of the symptoms and signs in such serious cases.

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04700.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SummaryOne hundred and twenty‐six children, 3 to 63 weeks of age, have been exposed to a mixed noise (100‐7000 Hz) in intensities between 50 and 80 dB under steady conditions of room acoustic during different periods of time between 10.30 p.m. and 01.00 a.m. A noise level of 75 dB led to obvious sleep disturbance or waking‐up in ⅔ of the children after 3 minutes and in all after 12 minutes. The waking threshold according to these investigations is higher than in adults.A 24‐hour recording of the noise level in different types of infants' and children's care units demonstrated that the acoustic stress– especially by “interior working‐noise”–in care units of light construction reaches or exceeds the obligate waking‐noise threshold of infants during most of the day and night hours. This is regarded as a deficienc

ISSN:0803-5253    

DOI:10.1111/j.1651-2227.1969.tb04701.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY