ISSN:0095-2990    

DOI:10.3109/00952997409011026

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

摘要:

This article describes the Drug Dependence Unit, a multimodality treatment agency which functions both independently and as an integral part of a community mental health center and a university medical school. Discussed are benefits and disadvantages of comprehensive care for drug-dependent individuals and problems incurred in the delivery of service to the selected population.

ISSN:0095-2990    

DOI:10.3109/00952997409011027

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

ISSN:0095-2990    

DOI:10.3109/00952997409011028

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

ISSN:0095-2990    

DOI:10.3109/00952997409011029

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

ISSN:0095-2990    

DOI:10.3109/00952997409011030

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

摘要:

Methadone maintenance is now an established modality in the management of heroin dependency. The ability of persons detoxified from methadone to remain opiate free has not been clearly defined. Of 490 consecutive admissions to a methadone maintenance program, 198 were subsequently detoxified. Follow-up on 168 persons (85%) was obtained for periods of up to 47 months. At the conclusion of the study, only 34 (17%) of those detoxified who were located were drug free. This represents 7% of the entire group of 490 persons admitted to the program. When ability to remain abstinent was correlated with reason for detoxification, 61% of those persons who the staff felt had received the maximum benefits of methadone maintenance were able to remain abstinent (p<0.005). These findings suggest that although it is possible to progress from methadone maintenance to abstinence, many persons will be unable to maintain

ISSN:0095-2990    

DOI:10.3109/00952997409011031

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

摘要:

Detoxification was evaluated in a long-term methadone treatment to ascertain how many reached a stable narcotic-free state. About 12% of the 396 patients ever admitted could be classified as stable, narcotic free at the time of interview, 14±5 months after their last methadone dose. Ten percent were judged to be functioning very well and 2% appeared to be doing poorly, i.e., abuse of alcohol particularly. Some patients could detoxify, many failed, and the majority seemed to be best treated with continuing methadone maintenance. Factors associated with successful detoxification included slow detoxification, full-time employment, positive motivation for detoxification, and high degree of assimilation into the nondrug world. Factors associated with the narcotic-free state were positive motivation for detoxification, high degree of assimilation into the nondrug world, and satisfactory completion of detoxification.

ISSN:0095-2990    

DOI:10.3109/00952997409011032

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

摘要:

A former heroin addict treated with methadone maintenance throughout pregnancy, with rapid dose reduction from 110 mg to 9 mg during the last five weeks pre-partum, was evaluated in late pregnancy, at time of labor and delivery, and post-partum; her child was also evaluated. Using gas and thin-layer chromatography and mass spectroscopy, methadone levels were measured, and other drugs looked for in (1) plasma during late pregnancy, (2) mixed cord blood, (3) amniotic fluid at delivery, (4) maternal plasma and milk post-partum (on 50 mg methadone), (5) neonatal plasma and urine. Low levels of methadone were present in amniotic fluid and neonatal urine but not in mixed cord blood or neonatal plasma. Levels of methadone present in breast milk during moderate dose maintenance were also low. Unexpectedly, pentobarbital was identified in amniotic fluid. Neonatal infection was also diagnosed. Multiple factors may have contributed to symtoms observed in the neonate.

ISSN:0095-2990    

DOI:10.3109/00952997409011033

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

ISSN:0095-2990    

DOI:10.3109/00952997409011034

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor

ISSN:0095-2990    

DOI:10.3109/00952997409011035

出版商:Taylor&Francis    

年代:1974

数据来源: Taylor