ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104467.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104468.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104469.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

ABSTRACTBetween 1970 and 1984,1138 patients underwent the insertion of 1300 prosthetic heart valves in Western Australia; 56% received an aortic‐valve replacement; 34% received a mitral‐valve replacement and 10% had more than one valve replaced. Mechanical valves were used in 93% of patients before 1977, in 20% of patients between 1978 and 1982 and in 70% of patients from 1983 onwards. The 30‐day mortality was 18% before 1973 and has been below 6% since 1974. The over‐all, 15‐year actuarial survival rate was 67%; this was not affected by age, sex, race, valvular position or the type of prosthesis. Both the 30‐day mortality and 15‐year survival rates were significantly worse in patients who underwent multiple valvular replacements (13% and 54%, respectively) or reoperation (16% and 58%, respectively). The major causes of death were cardiac failure and myocardial infarction (65%); endocarditis (13%); cancer (6%); and thromboembolism and bleeding (6%). The hazard rate for reoperation was low and fairly constant in patients with mechanical valves, but increased markedly after four years in patients with tissue valves. Although our experience so far suggests that survival rates are not affected by the choice of prosthesis, this may not be so in the future, as more patients with tissue valves undergo reoperation and so become exposed to an increased risk of mortality.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104470.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

ABSTRACTA synchronous chemoradiotherapy schedule of modest dosage has been used in 36 patients with oesophageal cancer since July 1984 at the Royal Adelaide Hospital. The schedule, which comprises two five‐day continuous infusions of 5‐fluorouracil, each of which is followed by a short cisplatin infusion, together with 30–35 Gy of megavoltage irradiation over three weeks, has been used alone, or before surgical resection or further chemoirradiation. It has been extremely well tolerated and has caused complete endoscopic resolution of disease before surgery or further chemoirradiation in 69% of patients. At the end of the full course of treatment, complete relief of dysphagia has been achieved in 27 (84%) of the 32 patients in whom this symptom was present at the start of treatment. The median duration of relief has not yet been reached with a median follow‐up of over one year. This degree of palliation is significantly better than that which was achieved in a series of patients who were treated radically either by surgery or radiation alone between the years 1978 and 1983 at the Royal Adelaide Hospital. The 12‐ and 18‐month actuarial survival figures of 72% and 55%, respectively, for the 30 patients in this series whose disease remained apparently localized to the thorax at presentation, compare very favourably with the corresponding figures for the much more highly‐selected group of patients who were treated surgically between 1978 and 1983.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104471.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

ABSTRACTSt Vincent's Hospital, Melbourne, is a 600‐bed acute teaching hospital with an active waiting list. The software for a stand‐alone, single‐user microcomputer was developed in‐house. The methods, advantages and problems that are associated with the system are presented.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104472.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

ABSTRACTPlasma magnesium concentrations were monitored daily in 86 patients who were admitted to a coronary care unit with a provisional diagnosis of acute myocardial infarction. Twenty‐six patients had suffered a myocardial infarction, while the remainder had angina or non‐cardiac chest pain. Magnesium levels were also obtained daily for five consecutive days in five normal subjects, who served as the control group. Calculations of the 95% confidence intervals on the differences between Day 1, Day 2 and individual subjects' mean plasma magnesium concentrations for the group with acute myocardial infarctions versus the group that did not have an acute myocardial infarction, the group with acute myocardial infarctions versus the reference group, and the group that did not have an acute myocardial infarction versus the reference group, and analysis of variance for the data from the three subject groups revealed no significant difference between the plasma magnesium levels of patients with an acute myocardial infarction and those with chest pain due to other causes or the normal reference population.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104473.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

ABSTRACTThree hundred and sixty‐two sera were examined by theLegionella pneumophilaindirect fluorescent antibody test, with serogroups 1 to 6 as antigens. Three age‐ and sex‐matched population groups were tested: 200 non‐Aborigines from Perth; 100 Aborigines from the Kimberley region; and 62 Aborigines from Jiggalong Mission in the Pilbara region. Each population group was composed of 50% male and 50% female subjects, all within the age range of 20 to 40 years. The seropositivity rate for serogroup 1 (Philadelphia) was 13% for the Perth populaton group, 26% for the Kimberley group and 35.5% for the Jiggalong group. Seropositivity rates with the other 5 serogroups for the Perth population group were as follows: serogroup 2, 1%; serogroup 3, 5%; serogroup 4, 3%; serogroup 5, 3%; and serogroup 6, 9.5%. In both of the Aboriginal population groups more subjects were seropositive to serogroups 3 and 5 than to serogroup 1. Multiple serogroup specificities and the occurrence of high titres were more common among the Aboriginal groups. These findings indicate that there is considerable variation in the prevalence ofL. pneumophilaantibodies among ecologically distinct groups within Western Australia.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104474.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104475.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb104476.x

出版商:Wiley    

年代:1988

数据来源: WILEY