ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120725.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120726.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120727.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

A sample of 400 Lebanese‐born women who gave birth at Auburn District Hospital in 1987‐1988 was compared with a sample of 400 Australian‐born women who gave birth in the same time period. The Lebanese‐born women were found to be older and of higher parity than were their Australian‐born counterparts; and to have booked their hospital admission significantly later in pregnancy than did the Australian‐born women. Lebanese‐born women also had frequently made a consanguineous marriage. Certain antenatal and intrapartum complications were more common in the Lebanese‐born women, and perinatal mortality and morbidity rates were higher among their infants. The particular problems of pregnancy in Lebanese‐born women, and possible ways of overcoming these, are discussed.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120728.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

Five hundred travellers to Bali were surveyed with a predeparture questionnaire to assess the source and nature of health advice for international travel that is provided to Australian tourists. Eighty‐seven per cent of travellers received some health advice for travel from either their family doctor, travel agent or both. Eighty‐nine per cent of travellers were advised to be immunized against typhoid and 75% of travellers were advised to receive a cholera vaccination; the proportion of travellers who underwent such therapy was the same irrespective of the standard of their accommodation in Bali or their likely risk of exposure to these infections. A y‐globulin injection was recommended to 18% of travellers and tetanus vaccine was recommended to 35% of travellers. General antimalarial measures were discussed with 59% of travellers, and 88% of travellers were advised to take antimalarial medications. Combined prophylaxis with chloro‐ quine and a sulpha drug (usually dapsone‐pyrimethamine [Maloprim]) was recommended most frequently (39% of travellers), with chloroquine alone (27% of travellers) or a sulpha drug alone (14% of travellers) also being prescribed commonly. A history of drug allergy was sought in 46% of the travellers who were advised to take antimalarial agents, and 41 % of travellers were informed of possible side‐effects of the antimalarial drugs. This survey showed that health advice about predeparture immunizations and antimalarial prophylaxis frequently differs from current recommendations of the Commonwealth Department of Community Services and Health and the World Health Organization.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120729.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120730.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

The technique of computed‐tomographic‐directed stereotaxic biopsy of cerebral lesions is described, and our series of 24 procedures on 23 patients without mortality or morbidity is presented. This technique provides neurosurgeons with an improved method of performing cerebral biopsies.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120731.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

The addition of the sulphonylurea agent, glibenclamide, to the insulin therapy of six patients with insulin‐dependent diabetes mellitus was studied in a double‐blind cross‐over trial. The subjects produced no measurable plasma C‐peptide after stimulation with glucagon, weighed within 10% of their ideal body weight and required approximately 1 U/kg per day of insulin. After one month of close supervision while the patients were being managed with diet and insulin therapy alone, glibenclamide, three times a day, or a placebo, was added to the therapy for one month. After a further one‐month control period, the alternate agent was administered for one month. No change in the insulin requirement or the glycosylated haemoglobin levels, or in the 24‐hour profiles of the plasma glucose and free insulin levels in response to a standard diet, was observed at the end of each treatment period. This study suggests that any enhancement of insulin sensitivity by sulphonylurea treatment in persons with insulin‐dependent diabetes mellitus is only minor and clinically‐unimportant.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120732.x

出版商:Wiley    

年代:1988

数据来源: WILEY

摘要:

Our review of the literature indicates that radiotherapy and/or heat therapy can provide local control of recurrent or metastatic melanoma in a large proportion of patients. This has undoubted value in the local palliation of symptoms and, in the absence of disseminated disease, can be curative. At The Prince of Wales Hospital, Sydney, we have studied the response of melanoma lesions to heat and radiation therapy and have assessed the reaction in the adjacent normal skin. Thirty‐two melanoma lesions that were measurable in 12 patients received radiotherapy and heat therapy in different combinations and dose schedules (15 lesions received radiotherapy alone, six lesions received heat therapy alone, and 11 lesions received combined radiation and heat therapy). The acute normal skin reaction was compared between lesions that received single modality radiation or heat therapy and those that received the combination of heat and radiation therapy. A moderate or severe reaction developed at six of the 21 sites that were treated by a single modality, and at four of the 11 sites that received combined heat and radiation therapy(P = 0.7),and all healed within a few days. Evaluation of the melanoma response to therapy was possible only in 26 of the 32 lesions that were treated because two patients died soon after therapy and the response of their six lesions was not evaluable. A complete response occurred in 14 (54%) of 26 lesions and a partial response occurred in 10 (38%) of 26 lesions. The objective response by treatment modality was 10 of 15 lesions for radiotherapy, six of six lesions for heat therapy and eight of 11 lesions for both therapies combined. We conclude that radiotherapy and heat therapy, separately or combined, produce acceptably‐low damage to normal tissue and highly‐satisfactory local control of melanoma.

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120733.x

出版商:Wiley    

年代:1988

数据来源: WILEY

ISSN:0025-729X    

DOI:10.5694/j.1326-5377.1988.tb120734.x

出版商:Wiley    

年代:1988

数据来源: WILEY