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| 11. |
Absence of the mental foramen in dry human mandibles |
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Cells Tissues Organs,
Volume 104,
Issue 3,
1979,
Page 353-355
V. de Freitas,
M.C. Madeira,
J.L. Toledo Filho,
C.F. Chagas,
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PDF (326KB)
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摘要:
The absence of the mental foramen was investigated in 1,435 dry human mandibles (2,870 sides). The foramen was absent twice in the right side (0.06%) and once in the left side (0.03%). The meaning of this anatomical variation was commented.
ISSN:1422-6405
DOI:10.1159/000145083
出版商:S. Karger AG
年代:1979
数据来源: Karger
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| 12. |
Teratogenic effects of a single oral administration of methylmercuric chloride in mice |
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Cells Tissues Organs,
Volume 104,
Issue 3,
1979,
Page 356-362
Masatoshi Fuyuta,
Toyoaki Fujimoto,
Eiiti Kiyofuji,
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PDF (833KB)
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摘要:
The teratogenic effects of methylmercuric chloride (MMC) given orally as a single dose to pregnant ICR mice on day 10 of gestation were examined. The doses tested were 25, 20, 15 and 10 mg/kg. Controls received distilled water orally. Each group consisted of 20 females. Fetuses were taken on day 18 of gestation for teratological study. The number of resorbed or dead embryos was moderately increased in the 25 mg/kg group. Fetuses from dams given 25, 20 and 15 mg/kg MMC weighed significantly less than those in the control group. Many fetuses with malformations were observed in the treated groups; cleft palate occurred in 100, 58.6 and 28.0% of fetuses from dams given 25,20 and 15 mg/kg MMC, respectively (statistically significant). Hydronephrosis appeared in 23.8 and 18.5% of fetuses from dams given 25 and 20 mg/kg MMC, respectively (statistically significant). Skeletal variations, incomplete ossification of sternebrae, for example, were also observed in the treated groups. These results indicate that MMC is teratogenic so far as cleft palate is concerned and embryotoxic in ICR mice.
ISSN:1422-6405
DOI:10.1159/000145084
出版商:S. Karger AG
年代:1979
数据来源: Karger
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