摘要:

The anlage of the spiral prominence can be seen on the 37th day of development as a small protrusion of the epithelium towards the lumen of the cochlear duct. During the further progress, the spiral prominence more distinctly protrudes by augmentation of the vascularized connective tissue. In the epithelial cells pinocytotic vesicles near the plasmalemma are seen earliest lateral and basal on the 37th day, apical on the 39th day. The epithelial cells send basal cytoplasmic extensions towards the connective tissue. Starting on the 44th day, small invaginations of connective tissue extend into the epithelium, remaining separated from the epithelial cells by the basal lamina. Until the 48th day, the monostratified epithelium remains columnar, thereafter it changes to cuboidal or flat. Towards the end of the development, the invaginations of the connective tissue nearly reach the surface of the epithelium, being separated from the endolymph by a small epithelial area.

ISSN:1422-6405    

DOI:10.1159/000145945

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Light and electron microscope observations of tiny nerve branchlets attached to the nerve of the pterygoid canal suggests that the source of sympathetic autonomic fibres in the greater petrosal nerve may not be solely confined to fibres ‘recurrent’ from the deep petrosal nerve, as hitherto belie

ISSN:1422-6405    

DOI:10.1159/000145946

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The submandibular gland in female and male Praomys (Mastomys) natalensis (a South African mul-timammate rodent) was studied using light microscopy and techniques for the demonstration of carbohydrates. Hematoxylin and eosin stain revealed the presence of a single secreting component that gave a strongly positive PAS reaction. Limiting elements of the granular tubules gave a weakly positive PAS reaction. Acidic glycoproteins were evidenced only in granules of the acinar component.

ISSN:1422-6405    

DOI:10.1159/000145947

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Bone growth and remodelling was studied in rats after injection of growth hormone, melanocyte-stimulating hormone (α-MSH), and cortisone daily for 20 days with tetracycline as intravital marker. An increase of both longitudinal and periosteal growth with growth hormone was found. A decrease of both was found after a high cortisone dose. Lower cortisone doses seem to have stimulated periosteal growth. No effect of α-MSH was foun

ISSN:1422-6405    

DOI:10.1159/000145948

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The effect of early postnatal protein malnutrition on the development of soleus muscle was investigated in 26 mice (13 males, 13 females). The control group received a balanced diet containing 18% lactalbumin while the protein-malnourished group received protein deficient diet containing 0.5% lactalbumin. The body weight was determined both at 3 weeks (weaning age) and 12 weeks of age. The soleus muscle weight, total number and sizes of muscle fibres were also determined at 12 weeks of age for each mouse. There was considerable retardation of body weight and soleus muscle weight. The smaller soleus muscle mass of protein-malnourished mice resulted from loss of muscle fibres and hypotrophy of the remaining fibres. Permanent retardation of body weight after recovery from early postnatal protein malnutrition may be as a result of loss of muscle fibres during that period.

ISSN:1422-6405    

DOI:10.1159/000145949

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The microcysts found in two adenohypophyses removed from patients with nonsecreting adenomas of this gland have been studied. In one case the cysts were completely surrounded by neoplastic tissue, whereas in the second they were located within the normal parenchyma. The cysts were surrounded by a basement membrane, and appeared to contain a finely granular weakly electron-dense substance. Their walls were lined by mostly cubic cells with microvilli, joined by junctional complexes. Intracytoplasmic microlumina could be seen in some of these cells. Cells showing cilia with a 9 + 2 fibrillar pattern and cells with mucosecretory differentiation were also present. Furthermore endocrine cells were also found in the cyst-lining epithelium. The ultrastructural aspects of the cyst cells lead to reject the hypothesis that these are derived from folliculostellate cells. Besides, intermediate aspects between cyst cells and tumor cells were never visible. Therefore it seems likely that a relationship between adenoma and cyst cells does not exist and that cyst cells originate from remnants of Rathke’s pouch with a ciliate or mucosecretory differentiation. The presence of endocrine cells in the cyst-lining epithelium deserves further study, for it seems to indicate that an endocrine differentiation may occur in the adult, too. To our knowledge this is the first ultrastructural study of these structures in adult human pituitary glan

ISSN:1422-6405    

DOI:10.1159/000145950

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The development of the interstitial endocrine (Ledig) cells of the fetal testis in the calf is described and correlated with a swelling reaction of the gubernaculum and normal, prenatal descent of the testis. An hydroxy-steroid dehydrogenase (HSD) procedure is used to determine the onset of functional activity for the interstitial endocrine cells (IEC). The NADH control procedure was strongly positive for the IECs at all ages investigated, indicating that these cells utilize the pyridine nucleotide as a coenzyme for oxireduction conversions. The 3α- and 3β-HSD reactions were strongly positive and lightly positive, respectively, demonstrating that these cells contain the HSDs commonly utilized in the early steroidogenesis. TEM revealed structural evidence of this differentiating steroidogenic capability within IECs. During the period of the swelling reaction there is a functional IEC population, but there is no evidence presented by this study for a causal relationship of the gubernacular swelling reaction and subsequent normal descent of the testis into the scrotu

ISSN:1422-6405    

DOI:10.1159/000145951

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The presence of macrophages in the outer bulb region of mouse, monkey and human Pacinian corpuscles was demonstrated by light and electron microscopy. In the normal, nontreated, Pacinian corpuscles, a few particular cells were located in the spaces between lamellae of the outer bulb. These cells contained numerous vesicles and vacuoles, and various cytoplasmic processes. When horseradish peroxidase (HRP) was injected locally or systemically, many HRP-positive cells, which were considered to be similar to the particular cells described above, were found in the outer bulb region of the corpuscles. Electron microscopy revealed that these cells contained HRP in vesicles and vacuoles, suggesting that they were macrophages vigorously taking up exogenous HRP. Macrophages in the Pacinian corpuscles are considered to work as scavengers to keep the inner environment of the corpuscles clear and constant with regard to its macromolecular content.

ISSN:1422-6405    

DOI:10.1159/000145952

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The cauda pancreatis has a characteristic pattern of vascularization. Among the big arterial stems surrounding it, up to 4 arteries, ‘caudal arteries’, nourish the arterial system of the cauda. These stems originate especially in the Arteria gastroepiploica sinistra and in the lower main splenic branch of the Arteria lienalis. The vascular relations between corpus and cauda can be of different kinds. Five basic types of relations can be identified: type I: the cauda is supplied exclusively by caudal arteries; type II: at least one caudal artery anastomoses with the vessels of the corpus; type III: the cauda is supplied both by the caudal arteries and by vessels of the corpus (non-anastomosing); type IV: combined forms of blood supply by caudal arteries and corpus arteries by way of anastomoses and non-anastomosing vessels are found; type V: the cauda is supplied exclusively be vessels stemming from the corpus. In each of these five types, individual vessels supplying the cauda can assume the function of a terminal ves

ISSN:1422-6405    

DOI:10.1159/000145953

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Mice were injected 3 times a day for 12 days with 8 µg/kg of somatostatin 14 which caused ahypoplasia of parietal and goblet cells, a hypotrophy and hypofunctionality of pancreatic acinar cells with a decrease in lipase and chymotrypsin activities, a decrease in the secretory function of the Brunner gland and in the number of dark granules of G cells. Neither villous and microvillous areas nor brush border hydrolase activities were affected. The number of peptic cells and Paneth cells increase as the level of pepsin and lysozyme. Mice were injected 4 times per hour with 2 µg/kg of somatostatin. 2 h after the first injection of somatostatin and 90 min after a single injection of tritiated thymidine, fundic, antral, jejunal and ileal labelling indexes strongly decrease (maximal effect in ileum). The inhibitory effect of somatostatin on the digestive epithelial cell proliferation compared to its long-term action only directed on specific cell types evokes probable compensatory mechanisms induced to maintain the equilibrium of the digestive epitheli

ISSN:1422-6405    

DOI:10.1159/000145954

出版商:S. Karger AG    

年代:1985

数据来源: Karger