摘要:

The development of adipose tissue lipoprotein lipase (LPL) activity was determined cytochemically in sections from normal and decapitated pig fetuses. Cellular LPL activity was first evident in 60-day-old fetuses. Capillaries were stained for LPL activity in 85-day-old and older fetuses and in young pigs. Cellular synthesis of LPL and capillary staining were not concurrent events. LPL activity developed after adipocyte differentiation and after structural development of capillaries. The cellular and capillary staining of fat cell clusters throughout development and in decapitated fetuses indicated a possible inverse relationship between cellular synthesis of LPL and capability of capillaries to transport LPL to luminal sides. These observations indicate that LPL activity develops in a pattern quite distinct from that observed in vitro. This discrepancy may be due to the involvement of blood vessels in the in vivo developmental pattern.

ISSN:1422-6405    

DOI:10.1159/000145598

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

127 abdominal aortas of children and adolescents aged 0–20 years were examined histomorphologically. The quantitative analysis gave the following results: (1) The intimal thickness increases continuously with age. The maximal intimal growth can be observed between the 1st and 3rd and the 12th and 19th year of age, respectively. (2) The media exhibits a similar increase in thickness with a maximal growth between the 1st and 3rd and in the 12th year. (3) The intima-media index rises rapidly from birth until the 3rd year, with a plateau thereafter, and then increases again between the 14th and 18th year. (4) The mean values for these measurements were higher in males than in females in all the age groups except for the 1st yea

ISSN:1422-6405    

DOI:10.1159/000145599

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Vascular connections occurring between the adrenal gland and the kidney were investigated by using techniques of ligation of renal arteries followed by injection of trypan blue into the thoracic aorta. These connections, which course through the renal capsule to terminate at the renal corticomedullary junction, were confirmed in the dog. Using the same techniques in the monkey and human, vessels could be traced to the renal capsule but did not appear to penetrate this capsule.

ISSN:1422-6405    

DOI:10.1159/000145600

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Weibel-Palade bodies were observed in the neoendothelium and capillaries of vasa vasorum of autologous ‘venous patches’ grafted in the common carotid artery of the rat. These corpuscules varied in number and distribution but were most frequently found in the luminal area of endothelial cytoplasm. In venous patch neoendothelium, the shape, size and substructure of Weibel-Palade bodies were similar to those in other types of vascular endothelium. These specific endothelial granules were more numerous during the week following neoendothelium formation. It is proposed that these corpuscules may play a role in the proliferation of endothelial cells in venous patc

ISSN:1422-6405    

DOI:10.1159/000145601

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Fetal mouse heart explants were cultured at 4 and 37 °C with or without chlorpromazine hydrochloride. Histological observations showed that tissue integrity was maintained at 4°C without or 37 °C with drug treatment. Tissue disintegration was observed at 4°C with drug treatment or 37 °C in the absence of the

ISSN:1422-6405    

DOI:10.1159/000145602

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The pattern of arrangement of superficial veins in the cubital fossa was studied in 400 cubital fossae of 200 living persons from amongst the medical students and staff of the Medical School, University of Calabar, Nigeria. In the present study, the patterns of arrangement of the veins in the cubital fossa varied considerably from usual textbook descriptions. Five types of variations have been observed. The commonest pattern observed was the median vein of the forearm dividing into two branches, one joining the basilic and the other the cephalic vein.

ISSN:1422-6405    

DOI:10.1159/000145603

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Male and female Sprague-Dawley rats were used to see if increased, intermittent, compressive forces, produced by experimental bipedalism would have a compensatory effect on hypophysectomy – a situation known to inhibit bone growth. Half of the rats underwent amputation of both front legs at 10 days of age; and at 21 days of age, half of the normal and half of the bipedal rats underwent hypophysectomy. All rats were sacrificed at 55 days of age, and weighed. The femora and tibiae were removed, cleaned, fixed, weighed and measured. The results of this study suggest that increased, intermittent, compressive forces may be instrumental in increasing long bone growth among adolescent female

ISSN:1422-6405    

DOI:10.1159/000145604

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The synthesis and transfer of proteins from the Schwann cell cytoplasm to the myelin sheath and axon of chicken embryos have been investigated with electron microscope radioautography. At early time intervals after the intravenous injection of 3H-proline into 18-day-old chicken embryos, the newly synthesized proteins are mainly collected in the Schwann cell cytoplasm with a preponderance in the Golgi area. Later, the bulk of labeled proteins migrate along the myelin sheath and a small portion is transferred to the axon. Most of the transferred proteins are conveyed through the regions of inner and outer mesaxons.

ISSN:1422-6405    

DOI:10.1159/000145605

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The distribution of β-galactosidase and β-glucuronidase in the forebrain of the hedgehog is similar to that of phospholipids. Both enzymes and the phospholipids are mainly localized in the fibrous components. Their distributional patterns are also identical to that of myelin. The functional significance of enzymes in lipid and myelin metabolism is discusse

ISSN:1422-6405    

DOI:10.1159/000145606

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Pregnant Sabra mice received 3 g phenobarbital per kilogram milled food from gestational days (GD) 9 to 18 as their only food source; control females received milled food. All the females were divided into three groups and injected intraperitoneally with a single dose of 3H-thymidine on GD 13, 15 or 17. At 50 days of age the offspring were perfused with 10% neutral formalin and their brains removed and prepared for autoradiography. Matching sagittal sections of the offspring were selected for the study of the medial preoptic area (MPOA) of the hypothalamus. The total number of cells per section was not significantly different between males and females, however, there was a greater cellular packing density (cell/mm2) in females (p < 0.05). This sex difference disappeared in treated offspring, possibly due to a 76% decrease on GD 13 in the rate of cell proliferation in females (number of labeled cells but not in males (p < 0.001); the greatest decrease in the number of labeled cells occurred in the sexually dimorphic areas of the MPOA (p < 0.001). The area of the sagittal section of the MPOA did not differ significantly between sexes or treatments.

ISSN:1422-6405    

DOI:10.1159/000145607

出版商:S. Karger AG    

年代:1982

数据来源: Karger