ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

The outcome of antidepressant treatment in 12 cases of electroconvulsive therapy (ECT)-resistant depression is presented. Eight patients had been refractory to a clinically adequate course of ECT (Hamilton Depression Scale improvement <20%) and four were partial responders (improvement 20–49%). All remitted completely on antidepressant medication within 2.2 ± 1.1 (mean ± SD) months of the ECT course. Remission was associated with clomipramine treatment (139 ± 49.7 mg/day) in seven cases and maprotiline (125 mg/day) in one case. Four patients who did not respond to a tricyclic antidepressant alone remitted following supplementation (of clomipramine in 2 cases, clomipramine + haloperidol in 1 case, and imipramine in 1 case) with lithium carbonate. Although a delayed therapeutic response to ECT cannot be excluded, the results suggest that ECT may alter the sensitivity of refractory patients to antidepressant medication.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

We measured15O water uptake and [18F]fluorodeoxyglucose (FDG) uptake in four depressed individuals before electroconvulsive therapy (ECT) and 24 h after completion of a series of six to 11 bilateral ECT treatments. Studies of radioactive uptake were done using positron emission tomography, with FDG as a measure for glucose metabolism and with oxygen-15-labeled water as a measure for cerebral blood flow. The four patients showed decreased uptake of FDG in the frontal cortex after ECT treatment. Two of the three patients in whom15O water was measured showed decreased uptake in the frontal cortex after ECT.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Three alternative monitoring methods for assessing the duration of seizures during electroconvulsive therapy were studied. The mean integrated amplitude of the electroencephalogram, facial muscle electromyogram, and “cuff method” were compared with the reference single-channel unprocessed electroencephalogram in 78 sessions with 17 patients. The measures of seizure duration differed significantly (p< 0.001). The mean integrated electroencephalographic amplitude differences were small and an artifact of the sampling procedure. Larger, but clinically unimportant, discrepancies were obtained with the facial electromyogram amplitude. In contrast, there were marked differences between the electroencephalogram and the “cuff method,” which suggest that the latter technique may be of limited usefulness.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Two groups of schizophrenic patients received either bitemporal or right temporoparietal electroconvulsive therapy (ECT), both without anesthesia. Each patient received six treatments, the first three at 2-day intervals and the next three at 4-day intervals. Psychiatric evaluations and cognitive tests done at baseline, and 7 and 20 days after therapy, found similar degrees of improvement and similar effects on memory in both groups, with improvement in 40% and impairment in 30% of the patients. Subjective forgetfulness is more often experienced by the patients who receive bilateral ECT.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A depressed male patient, who had his first affective disturbance as a complication of a right parietotemporal cerebrovascular accident, was treated with unilateral, nondominant electroconvulsive therapy, administered ipsilateral to the lesion. This procedure produced adequate seizure duration with excellent clinical results and without new neurological or neuropsychological deficits.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A patient is reported in whom pretreatment with intravenous lidocaine resulted in failure to elicit a seizure even at stimulus intensity markedly greater than that used successfully at prior and subsequent treatments. Together with one other report, this experience suggests that lidocaine may prevent a seizure by raising the seizure threshold. An alternative explanation is proposed for the classic findings of Ottosson that lidocaine-modified seizures are reduced in therapeutic efficacy.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Phencyclidine (PCP) abuse usually causes a short, self-limited period of intoxication but may lead to a prolonged psychosis, poorly responsive to antipsychotic medications. Prior reports indicate that electroconvulsive therapy (ECT) is a safe, rapidly effective treatment in such cases, but longer-term outcome has not been studied. We report three cases of PCP-associated psychosis that did not respond to at least 2 weeks of antipsychotic treatment but subsequently responded rapidly to ECT. Follow-up at 14 to 21 months after treatment show that recovery was maintained except in one subject who relapsed after continuing to abuse PCP. ECT should be considered as a treatment early in the course of drug-associated psychoses in which an adequate trial of antipsychotic medication has not been effective.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

A 61-year-old man with a severe conversion disorder with paralysis of his hand and consequent disuse atrophy was successfully treated with electroconvulsive therapy (ECT) when he was threatened with the loss of his hand. The experience of ECT in patients with conversion disorder is reviewed.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID

摘要:

Petit mal-grand mal (PM-GM) electroconvulsive therapy (ECT) is a technique developed by Impastato to elicit unconsciousness with a subconvulsive electrical stimulus, rather than with barbiturate anesthesia. Muscle relaxation is produced with succinylcholine chloride before stimulus is applied. The cases reported here illustrate applications of the technique to depressed patients with severe cardiac and pulmonary disease, and the use of PM-GM ECT in a patient in whom seizures could not be elicited by the usual ECT technique is described.

ISSN:0749-8055    

出版商:OVID    

年代:1988

数据来源: OVID