ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryPituitary hormone release after electroconvulsive therapy (ECT) may provide important information about certain of the effects of ECT on neurotransmitter function. Previously we quantified pituitary hormone release by the increase in the area under the hormone concentration/time curve. Swartz has rightly pointed out that this method ignores the rate of elimination of hormone and cannot be a measure of total hormone released. Swartz has proposed a kinetic model of hormone release, and in this paper we assess the reliability of parameters derived from it when applied to our own data on the effects of ECT on the release of prolactin and oestrogen-stimulated neurophysin. The deviations between observed and predicted values were small when only five post-ECT samples were used. Contrary to expectations, the goodness of fit did not improve when the number of sampling points was increased to nine after ECT. It was possible to fit a unique curve to the observed data in only 28 of 54 data sets. The reasons for these findings are discussed.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryIn a retrospective case control study, clinical features of postictal excitement following electroconvulsive therapy (ECT) were examined in 24 patients and 24 matched controls. The two groups did not differ in clinical outcome, degree of pretreatment agitation, anesthetic or succinylcholine dose, number of ECTs received, mean seizure duration, number of titrated treatments with subconvulsive stimulation, or type of EEG ending. Patients who became excited early in the treatment course rarely manifested this phenomenon at all subsequent treatments. Within the “excited” group, a minority of patients became excited following the first ECT, and only 34.3% of their treatments resulted in postictal excitement. It may not be necessary to routinely use postseizure benzodiazepines in patients who have once exhibited a postictal excitement.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryEpileptic grand mal seizures as well as electroconvulsive therapy (ECT) induce a transient robust prolactin hypersecretion. Similar prolactin response has been demonstrated following pentylenetetrazol (Cardiazol)-induced seizures in two schizophrenic female patients. A slight increase in cortisol secretion but no change in thyroid stimulating hormone and growth hormone levels suggest that the prolactin response is a specific hormonal change during convulsive treatments.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryThe time course of rectal temperature in mice was measured following a single and the last of 10 once-daily electroconvulsive shocks (ECS). In addition, temperature measurements were carried out following a single ECS 1 and 2 weeks after a course of 10 once-daily ECS treatments. After a single ECS, the animals showed a decrease of 2.3 ± 0.3°C, lasting for at least 90 min. Following the last of 10 ECS, the maximum response was markedly attenuated to 0.7 ± 0.1°C, and this attenuated response was present at least 1 week later. This effect may be mediated by alterations in postsynaptic α2-adrenoceptor or presynaptic 5-HT1Areceptor sensitivity, or may reflect a more fundamental resetting of temperature mechanisms.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryDopamine (DA) autoreceptor and postsynaptic receptor changes following repeated electroconvulsive shocks (ECS) were investigated in rats using the indices of low- and high-dose apomorphine-induced motility responses. Repeated ECS produced no changes in the DA autoreceptors; however, enhanced postsynaptic receptor-mediated responses were observed, suggesting increased sensitivity of the DA postsynaptic receptors.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryTo the numerous reports of the safety and efficacy of electroconvulsive therapy (ECT) in acute depressive episodes in patients with coexisting neurologic illness, the authors report their experience with two patients treated with maintenance ECT for more than 2 years. The authors find maintenance ECT useful in ameliorating the depressive illness without worsening the neurologic illness.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryAn elderly depressed female patient, who tolerated antidepressant drugs poorly, was found to have a small and asymptomatic meningioma before she was given electroconvulsive therapy (ECT). She received seven bilateral ECTs without neurological deterioration and had a good clinical result.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID

摘要:

SummaryCalculations reveal that the electroconvulsive therapy (ECT) stimulus cannot cause burn injury to brain tissue, but poor electrode-skin contact is a risk for skin burn. This article reviews factors that influence skin temperature, including electrical charge, skin impedance, topographic conformity between electrode and skin, electrode surface area, and thermal diffusivity of electrode material.

ISSN:0749-8055    

出版商:OVID    

年代:1989

数据来源: OVID