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| 11. |
Announcement |
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Science and Public Policy,
Volume 6,
Issue 3,
1993,
Page 222-222
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PDF (281KB)
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ISSN:0302-3427
DOI:10.1159/000211139
出版商:S. Karger AG
年代:1993
数据来源: Karger
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| 12. |
Influence of Ageing on the in vivo Mechanics of the Skin |
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Science and Public Policy,
Volume 6,
Issue 3,
1993,
Page 223-230
Yoram Lanir,
Vered Manny,
Abraham Zlotogorski,
Abraham Shafran,
Shabtay Dikstein,
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PDF (2806KB)
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摘要:
The response of the skin to common in vivo tests (in-plane uniaxial stretch, torsion, indentation and levarometry) is analyzed in terms of their suitability for ageing studies. The analysis suggests that low-load indentation and small deformation levarometry are well suited for ageing studies since the skin response under these tests can be directly related to its structure and constituent properties (known to be affected by ageing). The measured forehead skin response under these tests in ‘young’ (20–26 years) and ‘old’ (64–80 years) subjects is presented and compared with predictions of corresponding models. The results show that levarometry is more sensitive to ageing than i
ISSN:0302-3427
DOI:10.1159/000211140
出版商:S. Karger AG
年代:1993
数据来源: Karger
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| 13. |
Announcement |
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Science and Public Policy,
Volume 6,
Issue 3,
1993,
Page 230-230
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PDF (311KB)
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ISSN:0302-3427
DOI:10.1159/000211141
出版商:S. Karger AG
年代:1993
数据来源: Karger
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| 14. |
Effects of the Avène Spring Water on the Dynamics of Lipids in the Membranes of Cultured Fibroblasts |
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Science and Public Policy,
Volume 6,
Issue 3,
1993,
Page 231-240
L. Cézanne,
F. Gaboriau,
M. Charveron,
P. Morlière,
J.F. Tocanne,
L. Dubertret,
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PDF (1883KB)
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摘要:
In this preliminary report, dealing with the biological properties of Avène spring water, we investigated its effects on membrane properties of cultured human skin fibroblasts used as a model cell system. It is shown that incubation of these cells in the presence of Avène spring water brings about an increase in the fluidity of plasma membrane. This effect was evidenced by a decrease in the fluorescence anisotropy of the lipophilic probe diphenylhexatriene and by a 3-fold increase in the lateral diffusion coefficient of the lipophilic probe 5-(N-hexade-canoyl)-aminofluorescein, as measured through fluorescence recovery after photobleaching experiments. This effect reached a maximum for incubation times longer than 30 min and for a dilution of Avène water in laboratory water to about 20–25%. As discussed, changes in the hydrodynamic properties of cell membranes induced by Avène water provide a plausible explanation for some of the biological events this spring water is known to trigger.
ISSN:0302-3427
DOI:10.1159/000211142
出版商:S. Karger AG
年代:1993
数据来源: Karger
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