摘要:

In a patient without fluent speech, good comprehension, aphasia and frequent neologisms, computerized tomography (CT scan) demonstrated a left posterior thalamic hemorrhage sparing other language areas. We discuss the existence and the anatomical and pathogenetic mechanisms of thalamic aphasia.

ISSN:0014-3022    

DOI:10.1159/000115543

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000211851

出版商:S. Karger AG    

年代:1907

数据来源: Karger

摘要:

Prealbumin, was determined in serum, lumbar and ventricular cerebrospinal fluid (CSF) and compared with albumin and IgG. The measured concentrations of prealbumin in the CSF indicate that there are two sources of prealbumin: a minor fraction enters the CSF via the blood-cerebrospinal fluid (B-CSF) barrier like albumin, and the major fraction enters the CSF at the ventricles, probably during production of the CSF in the ventricles. The two fractions can be calculated from the CSF concentration of prealbumin, serum prealbumin and the concentration gradient (serum/CSF) of albumin. The B-CSF barrier-independent prealbumin can be used as an indicator of CSF circulation. This was proved by the investigation of several special cases.

ISSN:0014-3022    

DOI:10.1159/000115544

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

Report of 2 patients suffering from sensory peripheral neuropathy and multiple myeloma. In 1 case, peripheral neuropathy occurred several months before the appearance of multiple myeloma. A peripheral nerve biopsy exhibited numerous amyloid deposits within the endoneurium. Amyloid deposits have been estimated to occur in 15% of cases of multiple myeloma, but only 4 other detailed observations of amyloid deposits within the endoneurium have been reported in the literature. Other mechanisms might be involved since most peripheral neuropathies associated with multiple myeloma do not exhibit any amyloid deposits.

ISSN:0014-3022    

DOI:10.1159/000115545

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

A double-blind controlled trial was performed on 6 patients affected with Steinert’s disease in order to evaluate the efficacy of two different dosages of diphenylhydantoin (PHT, 200 and 300 mg/day) and carbamazepine (CBZ, 600 and 800 mg/day) on the myotonic afterdischarge. Both dosages of PHT and CBZ induced a significant improvement of myotonia. For PHT a trend towards decreased efficacy is pointed out at toxic or at high dosage

ISSN:0014-3022    

DOI:10.1159/000115546

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000211852

出版商:S. Karger AG    

年代:1907

数据来源: Karger

摘要:

Lisuride was administered to 63 patients with advanced Parkinson’s disease (PD) who were no longer satisfactorily responding to levodopa. The group included 40 patients with ‘on-off’ phenomena. Lisuride alone (13 patients) or combined with levodopa (50 patients) resulted in a 34% decrease in PD disability as assessed in the ‘on’ period, a 16% decrease in disability as assessed in the ‘off’ period, and a 96% increase in the numbers of hours in which patients were ‘on’ (from 5.5 to 10.8 h). All of these changes were significant (p ≤ 0.001). 37 of the 63 patients (59%) improved at least one-stage on lisuride. The major adverse effect limiting the use of lisuride was the occurrence of an organic confusional syndrome. This was related, in part, to the presence of an underlying dementia and to the concurrent use of an

ISSN:0014-3022    

DOI:10.1159/000115547

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

Clinical course, results of angiography and computerized tomography (CT) were compared in 204 patients with focal cerebral ischemias. The extent and the importance of the radiological results depend on the localization of the affected area, whereby essential differences exist between extra- and intracranial arteries as well as between the vertebrobasilar and the carotid arterial flow region. As to the carotid arterial system there appear to be significant correlations between the size of the infarction on the CT and the extent of the vessel stenosis on angiography. Furthermore the likelihood of deficit recovery is inversely proportional to the degree of pathology seen in both radiologic examinations. It is discussed whether these correlations, obtained from the examination of a great number of patients, can help to evaluate the significance of equivocal angiographic findings in individual cases.

ISSN:0014-3022    

DOI:10.1159/000115548

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000211853

出版商:S. Karger AG    

年代:1907

数据来源: Karger

摘要:

The first reported case of Pasteurella ureae meningitis associated with endocarditis is described. The patient pursued a fulminant deteriorating course despite appropriate antibiotic therapy begun within 24 h of presentation. Previous reports of Pasteurella ureae meningitis are reviewed. This organism should be considered in the differential diagnosis of gram-negative meningitis, since it is usually responsive to most antibiotics, including penicillin.

ISSN:0014-3022    

DOI:10.1159/000115550

出版商:S. Karger AG    

年代:1983

数据来源: Karger