摘要:

Motor behaviors on the ‘good side’ of the body, i.e. ipsilateral to the hemispheric lesion, have not been studied sytematically. We assessed motor behaviors in 20 consecutive patients during the acute phase (first 1-2 weeks) of a hemispheric stroke with hemiparesis. The behaviors were essentially rotations of the head, neck, eyes and trunk, orofaciopharyngeal or limb sterotypies, compulsive manipulation of the surroundings, or passive mobilization of the paralyzed arm or leg. These behaviors were found only with large infarcts in the territory of the internal carotid artery, middle cerebral artery and/or the anterior cerebral artery (ACA). All but two ACA infarcts involved the internal capsule and basal ganglia. The severity of the motor deficit and the presence of aphasia, neglect, or sensory loss were significantly correlated with the motor behaviors. Although the understanding of these behaviors remains unclear, we suggest that they may represent the clinical expression of early plastic changes of brain maps and circuits after an acute lesion; this is probably an active process induced by disinhibition, in order to establish new compensatory pathw

ISSN:0014-3022    

DOI:10.1159/000117085

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000119496

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

One-hundred thirty-six patients operated on for extra-axial tumors of the posterior and middle cranial fossae were retrospectively evaluated to define the relevance of trigeminal nerve dysfunction and to correlate clinical and surgical observations. The following data are reported: tumor types, presence of specific trigeminal symptoms and signs, mean duration of symptomatology, anatomical relation between tumor and fifth nerve. Trigeminal symptoms were present in 45 subjects (33.08%) with a mean duration of 23.56 months. Frequency of symptoms was different in various oncotypes. Fifth nerve disturbances were the symptom of onset in 18 subjects (13.23%). A tumoral involvement of the nerve was reported at surgery in 73 patients (53.67%) and was defined as contact, compression or infiltration. Postoperatively, 12 patients showed an improvement of fifth nerve disturbances. A statistically significant difference (p < 0.05) was found in: (1) the incidence of symptoms in patients with and in those without anatomical trigeminal involvement: (2) the incidence of signs in the same groups; (3) the incidence of postoperative relief in patients with fifth nerve compression compared to patients with different surgical findings; (4) the incidence of postoperative relief in patients with typical trigeminal neuralgia compared to those with other symptoms.

ISSN:0014-3022    

DOI:10.1159/000117086

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000119497

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

We reviewed 89 breast cancer patients with brain or epidural metastases in order to see whether a parallelism could be found between disease evolution inside and outside the central nervous system. One-fifth of the patients with brain metastases did not have any other site of relapse before neurological complication. Among the 38 patients who developed brain metastases and had a prior history of relapse outside the brain, 12 had control of distant extracranial sites while disease was progressing at these sites in 26 of them. In the epidural metastases group, all patients but 4 had progressive disease elsewhere when neurological complication appeared.

ISSN:0014-3022    

DOI:10.1159/000117087

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000203034

出版商:S. Karger AG    

年代:1914

数据来源: Karger

摘要:

Forty-five patients with CT findings of lacunar infarcts in the basal ganglia (LIBG) were included in this study. The patients were divided into those with lacunes in the caudate nucleus, lentiform nucleus or both caudate and lentiform nuclei. Linear measurements of ventricular spaces were also performed. Clinical evaluation disclosed parkinsonism in 17 patients (38%), strokes with contralateral hemiparesis in 14 (31%), while 9 (20%) had both parkinsonism and hemiparesis. The location and number of infarcts did not correlate with the clinical presentation. We conclude that LIBG are commonly associated with parkinsonism and that CT studies may help in the delineation of vascular parkinsonism.

ISSN:0014-3022    

DOI:10.1159/000117089

出版商:S. Karger AG    

年代:1995

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000119499

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

We report a case of clinically diagnosed corticobasal degeneration, in whom neuropsychological testing was performed along with functional imaging with IBZM SPECT. HM-PAO SPECT showed marked perfusion asymmetry in parietal cortical regions, lower to the right, contralateral to the most affected side. IBZM SPECT, which gives information about postsynaptic dopaminergic D2 receptors, showed severe reduction of tracer uptake in the right basal ganglia. Our findings suggest that a postsynaptic lesion in the basal ganglia might account for the lack of response of extrapyramidal motor symptoms to dopaminergic agonists in corticobasal degeneration.

ISSN:0014-3022    

DOI:10.1159/000117090

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

We report the existence of nephrocalcinosis (NC) and/or nephrolithiasis (NL) in three siblings with cerebrotendinous xanthomatosis (CTX). Incomplete renal tubular acidosis (RTA) type 1 is also found in these three siblings after the evaluation of renal acidification function. Although the association of RTA with NC and/or NL is well known, they are rarely reported in CTX patients.

ISSN:0014-3022    

DOI:10.1159/000117091

出版商:S. Karger AG    

年代:1995

数据来源: Karger