摘要:

We compared possible factors leading to symptomatic and asymptomatic reinfarcts in 207 patients an average of 2.1 years after their index athero-thrombotic stroke presenting with small subcortical infarcts. Symptomatic reinfarcts were mostly small infarcts in the perforating artery regions associated with angiographic evidence of atherosclerosis of parent arteries (large-artery disease), a high hematocrit, elevated fibrinogen and Lp(a) levels. They occurred with insufficient inhibition of platelet aggregability in patients receiving antiplatelet medication. In contrast, many asymptomatic reinfarcts were small perforator infarcts not associated with large-artery disease or cortical infarcts, and occurred in the absence of hematologic risk markers, and in spite of sufficient inhibition of platelet aggregability.

ISSN:0014-3022    

DOI:10.1159/000117027

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

Ten patients with left-sided visuospatial neglect due to cerebrovascular accident were monitored using the Behavioural Inattention Test (BIT) at weekly intervals, on a long-term basis. The novel finding was that some patients showed occasional but transitory marked improvement in their visuospatial neglect at times producing a normal score. This spontaneous phenomenon was evidenced by the patient cancelling sections or the entire block of left-sided targets, without any additional cues or prompts. Such episodes indicate that, in this small group of patients, visuospatial neglect is not necessarily irrevocable, at least for simple stimuli.

ISSN:0014-3022    

DOI:10.1159/000117028

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

We report 7 men (ages 45–61 years) with impotence associated with the Charcot-Marie-Tooth syndrome (CMT). The range of onset of erectile dysfunction varied from 38 to 55 years of age. One patient had classic CMT 1A with autosomal dominant inheritance, slow motor nerve conduction velocities and the 17p DNA duplication. One had probable type-II hereditary motor and sensory neuropathy. None of the patients had diabetes. There was some benefit from papaverine injection therapy or penile implants. The association of impotence with CMT is likely to be more common than previously recognize

ISSN:0014-3022    

DOI:10.1159/000117029

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

We report the first known patient with human T lymphotropic virus type I (HTLV-I) associated myelopathy (HAM) and myasthenia gravis (MG). A 50-year-old woman developed fluctuating muscle weakness with easy fatigability, transient bilateral blepharoptosis and double vision. Spastic paraparesis complicated these symptoms. Neurological assessments and specific laboratory findings revealed that the patient had definite HAM and MG. By inference from descreasing serum anti-HTLV-I antibody titers after thymectomy, the presence of antigenicity for HTLV-I in the thymic reticular cells, and a high incidence of various coexistent autoimmune diseases in HAM or MG, we suggested the possibility that these two diseases were associated with each other and with HTLV-I infection.

ISSN:0014-3022    

DOI:10.1159/000117030

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

We report on four patients with a histologically proven diagnosis of arteritis temporalis and clinical and/or neuroradiological evidence of severe focal cerebral ischemia due to intracranial vasculitis. While one patient suffered from a transient ischemic attack, CCT and MRI scans of the other patients showed multiple lacunar infarctions, combined with territorial infarctions in two cases. Necropsy in one patient demonstrated generalized giant cell vasculitis in large and small cerebral vessels. We suppose that the cerebral involvement was provoked by insufficient steroid therapy of arteritis temporalis in two patients. In one case, remission could be achieved by a combination of high-dose steroids and cyclophosphamide; one further patient remitted under lower steroid dosage. Steroid therapy was ineffective in two patients, one of whom died due to secondary complications. We conclude that central nervous system affection is a rare but dangerous complication of arteritis temporalis and may present as cerebral micro- and macroangiopathy.

ISSN:0014-3022    

DOI:10.1159/000117031

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

A left-handed Japanese man is reported who presented right-hand agraphia and tactile anomia following callosal infarction. Magnetic resonance imaging revealed an ischemic lesion extending from the posterior half of the trunk to the splenium of the corpus callosum. In his right handwriting, the ‘Kana’ (phonogram) was more severely impaired than the ‘Kanji’ (ideogram), and the most frequent typewriting error was morphological followed by neographism. His visuoconstructional ability was also more impaired in the right hand than in the left. Right-hand agraphia in our case is readily explained by the right hemisphere dominance both for language and visuoconstructional

ISSN:0014-3022    

DOI:10.1159/000117032

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

Hereditary neuropathy with liability to pressure palsies (HNLPP) is a peripheral nerve disorder in which recurrent pressure palsies are associated with pathological swelling (‘tomacula’) of myelinated nerve internodes. We report a patient with a slowly progressive polyneuropathy associated with substantial slowing of conduction velocities initially suggestive of an acquired or hereditary demyelinating polyneuropathy. However, repeat electrodiagnostic studies demonstrated that conduction slowing and partial conduction block were localized primarily to common sites of nerve compression and entrapment. Sural nerve biopsy revealed multiple tomacula consistent with the diagnosis of HN

ISSN:0014-3022    

DOI:10.1159/000117033

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

The case of an 18-year-old woman with Wernicke’s encephalopathy induced by hyperemesis gravidarum is reported. She had severe vomiting and received antiemetic therapy and intravenous administration of glucose and low-dose insulin solution without thiamine. She developed coma, nystagmus, ataxia and polyneuropathy. CT and MR imaging showed bilateral caudate lesions as well as symmetrical periventricular lesions of the thalamus and hypothalamus and periaqueductal gray matter. Caudate lesions are quite rare in Wernicke’s encephalopa

ISSN:0014-3022    

DOI:10.1159/000117034

出版商:S. Karger AG    

年代:1994

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000203143

出版商:S. Karger AG    

年代:1913

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000316537

出版商:S. Karger AG    

年代:1913

数据来源: Karger