摘要:

Fifteen well-documented Parkinson patients treated with Madopar were switched to Sinemet for 3 months. The results were measured with an objective test procedure and compared. The effects of Madopar and Sinemet were equal provided the amount of levodopa was the same. There was one drop-out, because of ventricular extrasystoles. Attention is paid to the occurrence of involuntary hyperkinesias and the on-off-effect.

ISSN:0014-3022    

DOI:10.1159/000114663

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

On basis of 35 patients who have suffered from transient global amnesia the pathophysiological mechanisms of this syndrome are discussed. Our impression is that the primary cause of this syndrome is a transient ischemia of the hippocampus, an opinion common with most earlier authors. The possibility of a unilateral hippocampal disturbance resulting in transient global amnesia is discussed. We are inclined to regard the local hippocampal ischemia as arising from insufficiency of the anterior chorioidal artery and thus as a sequel of internal carotid insufficiency, which has earlier been proved to result from various rotatory, flexion, and extension movements of the neck.

ISSN:0014-3022    

DOI:10.1159/000114664

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219443

出版商:S. Karger AG    

年代:1903

数据来源: Karger

摘要:

The results of brain scanning in 64 patients with histologically proven meningiomas are presented, and the accuracy of this diagnostic method is assessed. The five false-negative scans are analysed. This virtually harmless technique frequently provides sufficient information for the diagnosis in patients in whom more traumatic investigations would otherwise have been unavoidable.

ISSN:0014-3022    

DOI:10.1159/000114665

出版商:S. Karger AG    

年代:1975

数据来源: Karger

摘要:

Analysing the casuistry of 210 patients with basilar impression, the author has enumerated the type and frequency of the associated anomalies and looked for correlations between them and the various clinical syndromes. An attempt is made to divide the anomalies into pathogenetic groups on the basis of these findings.

ISSN:0014-3022    

DOI:10.1159/000114666

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219444

出版商:S. Karger AG    

年代:1903

数据来源: Karger

摘要:

In six patients with visual agnosia syndromes there was a striking dissociation between a preserved possibility of recognition of letters or objects in movement versus the recognition by simple visual static presentation. After a review of the literature it is concluded that at least two visual systems may be individualized in humans, i.e. a more recent one (the geniculo-calcarine) and an older one (the tectal-pulvinar-occipito-temporal system). Both from a physiological and clinical point of view, the most primitive system has two parts, i.e. a tectal and a telencephalic part. In visual agnosia, parts of the preserved primitive system remained as single support to compensate the loss of visual recognition for static patterns. The recognition of these two systems has both a theoretical and a practical value.

ISSN:0014-3022    

DOI:10.1159/000114667

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219445

出版商:S. Karger AG    

年代:1903

数据来源: Karger

摘要:

Cyclic adenosine-3’,5’-monophosphate (cAMP) concentration in cerebrospinal fluid (CSF) was measured by the protein binding method of Gilman from 62 neurological patients, 46 of them were epileptics and 16 with a central nervous system (CNS) damage. In epileptic patients the CSF concentration of cAMP was significantly elevated (p<0.02) for 3 days after an attack when compared with those free from attacks for at least 2 weeks. The causality relationship between the rise of cAMP in CSF and an epileptic discharge is discussed. In patients with an active or rapidly progressing CNS damage the cAMP levels in the CSF were significantly higher (p<0.001) than in those with an old CNS damage. Also some enzyme activities in CSF were measured but no uniform alterations could be found. In damaging processes of the CNS, the cAMP values in the CSF seem to correlate to the activity of the dise

ISSN:0014-3022    

DOI:10.1159/000114668

出版商:S. Karger AG    

年代:1975

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000219446

出版商:S. Karger AG    

年代:1903

数据来源: Karger