摘要:

The clinicopathologic picture of a case of so-called ‘sarcoglioma’ is reported. This tumor is characterized by a core of sarcomatous tissue, surrounded by an area of gradual transition from reactive to neoplastic glial cells; it occurs in children or in young adults and is very rare in comparison with the secondary sarcoma deriving from the vascular component of a glioblastoma (so-called ‘gliosarcoma’). The clinical and laboratory features and the pathology of this case are discussed in

ISSN:0014-3022    

DOI:10.1159/000116290

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The CT investigations of 156 children with partial epilepsies are analyzed. Pathological findings appeared in 39%, particularly atrophic changes and porencephalic lesions. According to the seizure type their incidence was higher in children who had secondary generalized seizures (46 %) than in children with isolated partial seizures (30%) or complex partial seizures with or without secondary generalization (16%). Furthermore, pathological findings occurred more frequently in children with perinatal etiology (37%) than in familial (26%) or idiopathic cases (10%). A symptomatic epilepsy due to a cerebral tumor or a vascular lesion was found in 10%. There was a high correlation between neurodevelopmental disturbances and abnormal CT findings, however also 17 neurological normal children had pathological CT findings.

ISSN:0014-3022    

DOI:10.1159/000116291

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

22 migraine patients with a history of chronic ergotamine abuse were compared with 12 patients with a similar intake of dihydroergotamine. The study of somatosensory-evoked potentials showed that 50% of the patients with a history of ergotamine abuse had increased central conduction times after stimulation of the tibial nerve. Corticomotoneuronal latencies obtained by noninvasive electrical stimulation of the motor cortex were normal in 5 patients. The functional sensory deficits were not related to clinical impairment and were more frequently observed in patients with a comparatively high mean daily and cumulative intake.

ISSN:0014-3022    

DOI:10.1159/000116292

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

A 46-year-old male patient was irradiated following left orchiectomy for seminoma. Three months after radiation, segmental myoclonus appeared involving all skeletal muscle groups up to the level of D10, the area of radiation. Urodynamic testing showed the presence of segmental myoclonus in the urethral sphincter. An around-the-clock ‘continuous segmental myoclonus’ during sleep and wakefulness with a frequency of 1 c/s and an amplitude of 400 µV selectively inhibited by REM sleep was not found in the literature. This continuous segmental myoclonus caused by a radiation myelopathy at D10-D11 was followed up for 2 years. It was partially controlled by carbama-ze

ISSN:0014-3022    

DOI:10.1159/000116293

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Acquired stuttering (AS) can follow unilateral right, left or bilateral hemispheric lesion, and can, but not necessarily, coexist with aphasia. In this paper we experimentally tested motor programming skills in a patient with AS of vascular origin. Motor programming consists in the structuration of the whole sequence of response prior to the onset of the first response element of a sequence of responses. Chronometric studies have shown that the time to initiate a sequence of manual responses is a function of the characteristics of the forthcoming sequence of responses. In our patient, reaction times involving single motor responses performed by right hand were within normal limit. On the contrary, when the task required a sequence of motor responses, there was a consistent difficulty in following the sequence: moreover, in the few correct sequences, reaction time analysis showed a lack of motor programming. It is suggested that AS could be the speech epiphenomenon of a more generalized disturbance of motor programming.

ISSN:0014-3022    

DOI:10.1159/000116294

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

A sensory disturbance limited to the hand or fingers and the corner of the mouth both on the same side constitutes the cheiro-oral syndrome (COS). Six patients with typical COS are described; in 5 of them a well-circumscribed lesion was found at different brain sites. Although this syndrome was formerly attributed to a parietal or thalamic lesion, a lesion at brainstem level also can cause COS. The pathogenetic explanation of this peculiar sensory symptom complex is a matter of debate and a new hypothesis is formulated. We advocate that when COS is encountered, especially if a history of migraine is lacking, a thorough neurological workup is called for.

ISSN:0014-3022    

DOI:10.1159/000116295

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Immunoinhibitory factors in the sera of stroke patients were studied by an analysis of their capacity to influence the in vitro proliferative response of T cells. The evidence was obtained that the sera from stroke patients exhibited inhibitory activity on T cell proliferation. Although the nature of these inhibitory factors was not analyzed, it was clearly shown that their activity correlated with the degree of neurological defects, indicating that their determination may be of some prognostic value.

ISSN:0014-3022    

DOI:10.1159/000116296

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The relationship between autonomic dysfunction and peripheral somatic neuropathy was investigated in uraemics. The battery of autonomic tests included R-R interval variation test, deep breathing, Valsalva manoeuvre, heart rate and blood pressure responses to standing, and sustained handgrip. Maximum conduction velocity along sensory and motor fibres of the posterior tibial nerve was measured. An impairment of parasympathetic reflexes was more frequent than a sympathetic damage, but with no relationship to the degree of electrophysiological disturbances. Cardiovascular autonomic dysfunction and somatic neuropathy in uraemia result to be two different entities in incidence and perhaps in pathogenesis.

ISSN:0014-3022    

DOI:10.1159/000116297

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Acute confusional state following metrizamide myelography has been reported to occur in up to 2 % of patients. These patients have been diagnosed as having toxic encephalopathy. Recently, various cases have been reported to have a nonconvulsive status (absence status or complex partial status) who responded well to diazepam or clonazepam therapy. However, some authors have described cases of nonresponders to anticonvulsive therapy. Failure of therapy can be dose-related. For this reason, our patient was closely monitored by EEG to determine if dose adjustment was warranted, thereby achieving good results.

ISSN:0014-3022    

DOI:10.1159/000116298

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Three patients with unusual presentations of basilar artery ectasia are described: subarachnoid hemorrhage was manifest in one and autonomic dysfunction developed in the other two. Aneurysmal rupture was the cause in the first patient, while compression of the brainstem and/or of the baroreceptor afferences of the IXth and Xth cranial nerves is postulated to be responsible for the symptoms found in the other two. Basilar artery aneurysms should be considered in cases with subarachnoid hemorrhage or autonomic dysfunction, particularly when diagnostic procedures fail to disclose other possible etiologies.

ISSN:0014-3022    

DOI:10.1159/000116299

出版商:S. Karger AG    

年代:1988

数据来源: Karger