摘要:

Ultrastructural studies of peripheral nerves and motor end-plates are performed in a case of neuroaxonal dystrophy already diagnosed on the basis of clinical and morphological data (brain biopsy). Lesions similar to those described in the central nervous system are found in the extra- and intrafusal axons and motor end plates. The sensory nerve shows only discrete alterations. Although it is widely recognized that many other diseases are characterized by the presence of axonal spheroids, the combination of the relevant clinical data and the positive results of a motor end-plate biopsy allow the diagnosis of infantile neuroaxonal dystrophy to be made, obviating or alleviating the need of a brain biopsy.

ISSN:0014-3022    

DOI:10.1159/000114583

出版商:S. Karger AG    

年代:1972

数据来源: Karger

摘要:

A patient suffering from torsion dystony presenting abnormal copper metabolism is reported. Low ceruloplasmin concentration was found in other members of his family. The problem of the causal relationship between torsion dystony and abnormal copper metabolism is discussed.

ISSN:0014-3022    

DOI:10.1159/000114584

出版商:S. Karger AG    

年代:1972

数据来源: Karger

摘要:

Within the optic and acoustic ranges of perception, the reaction periods and selective reaction periods of 40 patients suffering from multiple sclerosis were compared with those of 40 healthy control persons. The reaction time and the selective reaction time of the patients were significantly longer (p<0.05) than those of the controls. The patients selective reactions were most prominently affected. The selective reactions of the patients were more significantly delayed within the range of acoustic perception than within the optic range (p<0.01). There is not enough material in this work to prove a correlation between the changes of reaction time or selective reaction time and the duration of the disease or the number of phases. In the discussion, reference is made to the changes of functional parameters of demyelinated nerve fibres. The disturbances found can be regarded as due to functional changes of demyelinated nerve fibres in CNS, particularly in the cerebral white matter.

ISSN:0014-3022    

DOI:10.1159/000114585

出版商:S. Karger AG    

年代:1972

数据来源: Karger

摘要:

The literature lists a number of methods of EMG examination which afford information on supranuclear motor disturbances. A number of these tests were selected for further evaluation. These tests yielded 24 EMG variables. Three groups of test subjects were studied: 39 normal test subjects, 27 patients with spastic syndrome and 23 patients with a Parkinson syndrome. Efforts were made to establish which EMG tests can contribute to differentiation of these three categories. The following test battery yielded sufficient relevant information: (a) testing the KJR, ATR and HR, using skin electrodes; (b) testing an agonist and antagonist at relaxation and slow passive stretching, using needle electrodes; (c) if necessary, supplementary testing of the vibration reflex. Spastic patients show an increased KJR with Jendrassik (m 4.6 mV), A/M quotient (m 0.31), H/M quotient (m 0.50), and usually a positive stretch reflex; the vibration reflex is diminished (m 8.2°). Parkinson patients show no electrical silence at relaxation but spontaneous action potentials, irregular groups of action potentials and/or tremor (frequency m 4.6/sec), and usually a positive stretch reflex

ISSN:0014-3022    

DOI:10.1159/000114586

出版商:S. Karger AG    

年代:1972

数据来源: Karger

摘要:

The result of plexectomy in 22 cases of hydrocephalus is reported. The technique used, characterized by the insertion of a self-retaining plastic retractor in the ventricle avoiding the collapse of the pallium, has a very low mortality rate (2.8%). Stabilization of hydrocephalus was achieved in 63.6% of which 42% resulted in a good psychomotor development. Plexectomy probably reduces liquor production to an extent which permits an equilibrium between production and resorption. Without leaving behind any foreign body, this technique produces results which can be compared to those obtained after shunt operations.

ISSN:0014-3022    

DOI:10.1159/000114587

出版商:S. Karger AG    

年代:1972

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000114588

出版商:S. Karger AG    

年代:1972

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000114589

出版商:S. Karger AG    

年代:1972

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000221521

出版商:S. Karger AG    

年代:1900

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000221522

出版商:S. Karger AG    

年代:1900

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000221523

出版商:S. Karger AG    

年代:1900

数据来源: Karger