摘要:

Two groups of patients who had a stroke, prolonged reversible ischaemic neurological deficit or transient ischaemic attacks were compared; one group was treated with anticoagulants (phenprocoumon) and a matched control group was treated with other substances. Results showed a similar survival rate in both groups, but significantly fewer recurrences were seen in the surviving patients treated with anticoagulants.

ISSN:0014-3022    

DOI:10.1159/000115070

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

Cytological changes in 9 samples of cerebrospinal fluid (CSF) from 5 patients with zoster meningitis and 12 samples from 5 patients with radiculomeningitis after tick bite were examined. 5 days after the onset of the skin eruption, the CSF cells in zoster meningitis consisted of many mononuclear blast forms – large lymphocytes and ‘immature’ plasma cells. 11–15 days after the onset of the skin rash, they were replaced by small lymphocytes, some ‘mature’ plasma cells and monohistiocytes. In radiculomeningitis after tick bite, however, the CSF cells examined 10–21 days after the onset of radicular pain consisted of many large lymphocytes, immature plasma cells and a few neutrophils. From these findings, it might be suggested that the acute meningeal reaction of zoster meningitis subsides within about 1 week after the onset of the skin rash, but that of radiculomeningitis after tick bite continues at least for 2–3 weeks after the onset of

ISSN:0014-3022    

DOI:10.1159/000115071

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

Levator palpebrae (m. lev. palp.) and rectus superior (m. rect. sup.) are two synergistic muscles in vertical gaze movements. However, they show an antagonistic behavior during electrically induced blink and glabellar reflexes. This can be considered as an easy and useful method for their differentiation in the electrophysiological study of certain oculopalpebral motor disorders. Blinking consists of a series of reflex activities, the most outstanding ones being an early m. lev. Palp. basal activity inhibition, followed by the activation of the orbicularis oculi muscle and a brief increase in m. rect. sup. activity (reflex Bell phenomenon). This coordinated reflex organization could be perfectly related to that known in other human nociceptive reflexes.

ISSN:0014-3022    

DOI:10.1159/000115072

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

307 probands with febrile convulsions classed as the simple type (131 children) and the complicated type (176 children) were genetically analyzed. There was a tendency toward familial aggregation of febrile convulsions, and genetic involvement was suggested. The multifactorial mode of inheritance best agreed with the observations. (1) The ratio of incidence of febrile convulsions in siblings of probands in the present study (19.9%) to the incidence in the general population (2.9%), i.e., 6.85, was rather close to the expected ratio of 5.87 from the multifactorial inheritance system. (2) The incidence in siblings tended to be higher when either or both of their parents had a history of febrile convulsions. In 2-child families where the first child was affected, the incidence in the second child tended to increase in parallel with the increasing incidence in parents. (3) The incidence in siblings was higher if probands were males. (4) The heritability, when estimated by Falconer’s procedure, was as high as 76%, showing that febrile convulsions are strongly genetically predisposed. These findings were more distinctly observed in the simple type than in the complicated typ

ISSN:0014-3022    

DOI:10.1159/000115073

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

T lymphocytes were determined according to their ability to form rosettes with sheep erythrocytes, in cerebrospinal fluid (CSF) from 120 patients, and in peripheral blood from 59 patients. Normal CSF contained 74.9 ± 9.6% T lymphocytes. Increased T lymphocyte percentage was found in CSF from patients with active multiple sclerosis (MS), and Guillain-Barré syndrome, as well as the 2 patients with retrobulbar neuritis and the 1 with subacute sclerosing panencephalitis. Patients with stable MS showed no significant change in CSF T lympohcyte percentage. CSF from patients with viral meningo-encephalitis or meningo-radiculitis had a decreased T lymphocyte percentage. This decrease was also found in the 2 patients with malignant disease and the 2 with presenile dementia. An exceptionally low CSF T cell count (5%) was found in 1 patient with cerebellar ataxi

ISSN:0014-3022    

DOI:10.1159/000115074

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

The effect of phytohemagglutinin (PHA) and pokeweed mitogen (PWM) on blood lymphocytes was studied in multiple sclerosis, patients with acute CNS infections, and healthy controls. No significant differences in lymphocyte proliferation were registered between the group of MS patients and the two other groups, irrespective of mitogen used. The ratio between the PWM and PHA responses did not differ significantly from the ratios in the two other groups. The lymphocyte proliferation with PWM was significantly lower in the group with acute CNS infections compared with controls. The results indicate that alterations in cell-mediated immunity, if present in MS, are not confined to lymphocytes outside the CNS.

ISSN:0014-3022    

DOI:10.1159/000115075

出版商:S. Karger AG    

年代:1979

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000213431

出版商:S. Karger AG    

年代:1906

数据来源: Karger

摘要:

A case of classical Sturge-Weber syndrome associated with infantile spasms (female infant, aged 4 months) was presented. The association of both conditions would be very rare since no similar case was found among 214 cases of Sturge-Weber syndrome and 1,180 cases of infantile spasms gathered from the literature, except for one who was reported by Millichap et al. Evolutional changes of electroencephalographic findings were followed up for about 3 years on average in 5 personal cases of Sturge-Weber syndrome. Unilateral depression of electrical activity in the cerebral hemisphere ipsilateral to the facial nevi was the constant finding. Focal spike discharges were noticed only in the contralateral hemisphere in 3 cases, only in the ipsilateral in 1, and in the bilateral in 1.

ISSN:0014-3022    

DOI:10.1159/000115076

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

Clinical amelioration, clearance of Kayser-Fleischer rings and rising of ceruloplasmin concentration are described in a patient with the classical findings of Wilson’s disease. These changes occurred during a 14-year period in which he used oral zinc sulphate (three times daily 200 mg) as the only medication to influence copper metabolism. Before starting this long-term zinc sulphate therapy he had used D-penicillamine (three times daily 300 mg) for only 6 weeks. The antagonistic action of zinc sulphate on copper resorption with amelioration of the clinical condition has been described before in this patient in 1961 by Schouwink. The patient had used at that time oral zinc sulphate for approximately 1.5 years. No changes in Kayser-Fleischer rings and ceruloplasmin levels were mentioned. Our findings suggest that oral zinc sulphate may not only prevent storage of copper in the tissues but may also contribute to the mobilization and excretion of deposits of coppe

ISSN:0014-3022    

DOI:10.1159/000115077

出版商:S. Karger AG    

年代:1979

数据来源: Karger

ISSN:0014-3022    

DOI:10.1159/000316433

出版商:S. Karger AG    

年代:1906

数据来源: Karger