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11. |
Localization of the human 75-kDal Fe-S protein of NADH-coenzyme Q reductase gene (NDUFS1) to 2q33→q34 |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 212-213
A.M.V. Duncan,
W. Chow,
B.H. Robinson,
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摘要:
The gene for the human 75-kDal Fe-S protein of the NADH-coenzyme Q reductase was localized to 2q33→q34 by in situ hybridization to human metaphase chromosomes banded, by BrdU-incorporation, to the 500–550 band level of resolut
ISSN:1424-8581
DOI:10.1159/000133340
出版商:S. Karger AG
年代:1992
数据来源: Karger
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12. |
The KDR gene maps to human chromosome 4q31.2→q32, a locus which is distinct from locations for other type III growth factor receptor tyrosine kinases |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 214-215
B.I. Terman,
S. Jani-Sait,
M.E. Carrion,
T.B. Shows,
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摘要:
KDR (kinase insert domain receptor), a new type III receptor tyrosine kinase gene, maps to human chromosome 4q31.2→q32 by fluorescence in situ hybridization. This differs from the chromosomal locations of other members of this gene famil
ISSN:1424-8581
DOI:10.1159/000133341
出版商:S. Karger AG
年代:1992
数据来源: Karger
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13. |
Localization of two new DNA markers on the linkage map of human chromosome 6q |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 216-218
B.C. Byth,
D.R. Love,
J.C. Murray,
K.E. Davies,
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摘要:
Recently, an autosomal homolog of the dystrophin gene (DMDL) was identified on chromosome 6q24. As part of our analysis of the DMDL locus, we endeavoured to isolate DNA markers to further define the genetic map of this region. We have isolated and characterized two new genetic markers in the region of the DMDL locus, the RFLP D6S129 and a (CA)n dinucleotide repeat polymorphism within the DMDL gene itself and have positioned them on the existing genetic map of chromosome 6q. These markers will be important in testing the hypothesis that the DMDL gene is the locus responsible for autosomal forms of neuromuscular disease.
ISSN:1424-8581
DOI:10.1159/000133342
出版商:S. Karger AG
年代:1992
数据来源: Karger
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14. |
Somatic cell mapping of the human cyclophilin B gene (PPIB) to chromosome 15 |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 219-221
L.B. Peddada,
J.D. McPherson,
R. Law,
J.J. Wasmuth,
P. Youderian,
R.J. Deans,
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摘要:
The polymerase chain reaction (PCR) technique was used to generate a unique probe complementary to the hydrophobic 5’ end of the human cyclophilin B gene. This unique probe was hybridized to DNAs from human × hamster hybrid somatic cell lines retaining different combinations of human chromosomes. The gene was assigned to chromosome
ISSN:1424-8581
DOI:10.1159/000133343
出版商:S. Karger AG
年代:1992
数据来源: Karger
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15. |
Assignment of the rat genes coding for substance P receptor, substance K receptor, and neuromedin K receptor to chromosomes 4, 20, and 2, respectively |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 222-223
M. Mori,
Y. Yokota,
M. Yasue,
T. Serikawa,
J. Yamada,
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摘要:
Three tachykinin receptor genes: substance P receptor gene (gene symbol; TAC1R), substance K receptor gene (TAC2R), and neuromedin K receptor gene (TAC3R) have been assigned to rat chromosomes 4, 20, and 2, respectively, by using cDNAs for the rat TAC1R, TAC2R, and TAC3R genes and a rat × mouse somatic cell hybrid panel which segregated rat chromosomes
ISSN:1424-8581
DOI:10.1159/000133344
出版商:S. Karger AG
年代:1992
数据来源: Karger
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16. |
Germ line-restricted supernumerary (B) chromosomes inEptatretus okinoseanus |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 224-228
S. Kubota,
Y. Nakai,
M. Kuro-o,
S. Kohno,
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摘要:
Cytogenetic studies were performed on two types of Japanese hagfish (Eptatretus okinoseanus) that eliminate about 45% (type A) and 55% (type B) of their DNA from presumptive somatic cells during the differentiation of somatic cells. The observations revealed inter- and intraindividual variations in the number of chromosomes in germ cells of both types of hagfishes. Although the modal number of chromosomes in the germ cells was 54 in both types, the percentage of cells with the modal number was rather low (38.6% [51/132] in five specimens of type A and 22.7% [25/110] in eight specimens of type B). In addition, one of seven type B specimens clearly had a modal number of 62 chromosomes. Another specimen of type B had a bimodal distribution of chromosome numbers, with peaks of 54 and 59 chromosomes. The observation of interindividual variations was supported by data on the amount of DNA in germ cells of type B specimens. However, these variations were rarely observed in somatic cells. These results suggest that supernumerary (B) chromosomes are maintained in germ cells and are eliminated together with some other chromosomes and/or chromatin from somatic cells.
ISSN:1424-8581
DOI:10.1159/000133345
出版商:S. Karger AG
年代:1992
数据来源: Karger
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17. |
Cytogenetics of bisexual/unisexual species ofPoecilia |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 229-235
L. Sola,
AR. Rossi,
V. Iaselli,
EM. Rasch,
PJ. Monaco,
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摘要:
Chromosomes of Poecilia mexicana mexicana, one of the bisexual species involved in the hybrid origin of the unisexual teleost fish species P. formosa, were analyzed by several staining techniques. Sex-specific, differential heterochromatin, found in other congeneric species, was not observed in P. m. mexicana. Nucleolar organizer regions were polymorphic among individual specimens within a given population sample. A single specimen exhibiting intraindividual variability of chromosome pair 1 and a specimen with a triploid karyotype are also described.
ISSN:1424-8581
DOI:10.1159/000133346
出版商:S. Karger AG
年代:1992
数据来源: Karger
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18. |
Cytogenetics of bisexual/unisexual species ofPoecilia |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 236-240
L. Sola,
V. Iaselli,
A.R. Rossi,
E. M. Rasch,
PJ. Monaco,
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摘要:
Chromosomes of the Amazon molly, Poecilia formosa, a unisexual species of hybrid origin, were investigated by C-banding, silver staining, and fluorescent staining with DAPI, quinacrine dihydrochloride, and chromomycin A3. Analysis of heterochromatin distribution indicates that chromosomes similar to the W chromosome of P. latipinna are not present in the unisexual species. Therefore, morphologically differentiated sex chromosomes do not form the basis of the unisexuality in P. formosa. The number and location of nucleolar organizer regions vary in P. formosa and do not correlate well with those of the parental species.
ISSN:1424-8581
DOI:10.1159/000133347
出版商:S. Karger AG
年代:1992
数据来源: Karger
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19. |
Assignment of the NRAS protooncogene to chromosome 12 of Syrian hamster by in situ hybridization |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 241-244
T. Issa,
R. Porter,
E.M. Parry,
J.M. Parry,
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摘要:
The NRAS protooncogene codes for a GTP binding/GTPase p21 protein which resides on the inner surface of the plasma mebrane. Using a human cDNA probe for NRAS, we have assigned the gene to Syrian hamster chromosome 12 with the most likely localization being 12qa5.
ISSN:1424-8581
DOI:10.1159/000133348
出版商:S. Karger AG
年代:1992
数据来源: Karger
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20. |
Localization by in situ hybridization of a type I keratin intermediate filament gene (Krt-1.14) to band D of mouse Chromosome 11 |
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Cytogenetic and Genome Research,
Volume 60,
Issue 3-4,
1992,
Page 245-246
A.T. Correll,
G.C. Webb,
J.H. Ford,
G.E. Rogers,
B.C. Powell,
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摘要:
A probe from the 3’ noncoding region of a murine type I keratin intermediate filament (IF) gene (Krt-1.14) localizes to band D of murine Chromosome 11 using in situ hybridization. This localization provides a physical confirmation of the assignment of the type I keratin genes by linkage analysis in the mouse. It also demonstrates that the Krt-1.14 genes are at a single locality in the mouse in contrast to the two locations on the short and long arms of chromosome 17 in human
ISSN:1424-8581
DOI:10.1159/000133349
出版商:S. Karger AG
年代:1992
数据来源: Karger
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