摘要:

The genes encoding calbindin D28k (CALB1) and calretinin (CALB2), two closely related calcium-binding proteins, were mapped by in situ hybridization to the 8q21.3→ q22.1 and 16q22→q23 regions of the human genome, respectively. These localizations match the chromosomal regions where the carbonic anhydrase isozyme gene cluster (CA1 CA2, CA3) and the related gene CA7 have been described, respectively. This suggests a common duplication·the calbindin/calretinin and the carbonic anhydrase ancestral g

ISSN:1424-8581    

DOI:10.1159/000133111

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

The porcine aminopeptidase N (PEPN) gene was shown to be syntenic with the porcine major histocompatibility complex (SLA) using Southern blot analysis of a pig × mouse hybrid cell panel. Regional localization of the PEPN gene to 7cen→q21 was performed by in situ hybridization. The results suggest that synteny of the genes for mannose phosphate isomerase and PEPN is conserved in pig and m

ISSN:1424-8581    

DOI:10.1159/000133112

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

The genes for proacrosin, protamines, and transition proteins are exclusively expressed in haploid spermatogenic cells. From the analysis of mouse × rat cell hybrids which segregate rat chromosomes, the rat gene for proacrosin (ACR) was assigned to chromosome 7, that for transition protein 1 (TNP1) to chromosome 9, and the genes for transition protein 2 (TNP2) and protamine 1 (PRM1) to chromosome 10

ISSN:1424-8581    

DOI:10.1159/000133113

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

The karyotypes of the three main domestic Bovidae species, Bos taurus, Ovis aries, and Capra hircus, have been investigated by RBG-banding. Primary fíbroblast cells were cultured from fetal lung or muscle tissue and collected for chromosome preparation after double thymidine synchronization. Depending on the culture and species, BrdU and FdU were added for 8–11 h or 7–10 h, respectively, before harvest. The chromosomes of the three species were classified and numbered according to standard conventions (ISCNDA, 1989) and compared at different stages of condensation. Within the resolving power of the images obtained, the RBG-banding patterns appear to be very similar, with only minor differences existing between chromosome 9 and the sex chromosomes of cattle and the same chromosomes in the domestic sheep and the

ISSN:1424-8581    

DOI:10.1159/000133114

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

Conventional and microspread preparations of Microtus cabrerae spermatocytes were made to investigate the chromosomes of this species. Three different types of Y chromosomes, varying in size of the heterochromatic block, were observed; they were alike, however, in regard to synapsis, which was consistently absent. Our results suggest that the heterochromatic blocks are not involved in the lack of synapsis and that asynapsis is a cytological feature common to all species of the family Microtidae. In addition, the co-aligned configuration of the ends of the sex-chromosome axes of this species and the lack of silver-stainable threads or filaments connecting them suggest the existence of two mechanisms for association of the sex chromosomes during prophase I and metaphase I: attachment of the ends of both sex chromosome axes to the nuclear envelope and heterochromatin “stickiness

ISSN:1424-8581    

DOI:10.1159/000133115

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

A human genomic DNA sequence derived from glutamate dehydrogenase pseudogene 1 was used as a probe for in situ hybridization to the chromosomes of three lemur species, Eulemur fulvus mayottensis (EFU), E. macaco macaco (EMA), and E. coronatus (ECO). This sequence, which is 98 % homologous to the nucleotide sequence of the gene for human glutamate dehydrogenase (GLUD), was found on homologous bands of three morphologically similar chromosome segments, EFU14, EMA5p, and EC08q, confirming that different Robertsonian translocations occurred during the evolution of these three species. These loci on the lemur chromosomes probably correspond to the human GLUD locus.

ISSN:1424-8581    

DOI:10.1159/000133116

出版商:S. Karger AG    

年代:1991

数据来源: Karger