摘要:

Silver nitrate has been used to demonstrate the chromosomal location of ribo-somal cistrons in nine tissue-culture lines derived from human tumors of various pathological origins. Control individuals have a particular modal number (range 7–10) of D- and G-group chromosomes stained with silver. In the controls, 96.2 % > of the D- and G-group chromosomes that have a stalk show silver staining, while no relationship can be seen in acrocentric chromosomes without stalks. The tumor cells, whose modal chromosome numbers range from 42 to 68, possess variable numbers of acrocentrics (11–18). The number of chromosomes stained with silver, however, remained at control levels (range, 6–9). These data indicate that, in humans, silver staining may not identify all NORs that contain structural ribosomal

ISSN:1424-8581    

DOI:10.1159/000130808

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The quantitative expression of LDH A was studied in hemolysates from four patients with different but overlapping interstitial deletions of the short arm of chromosome 11. Deficiency of LDH A was demonstrated in one patient, and the LDH A locus has been assigned to that segment of lip for which this patient alone was deficient, i.e., to band llpl2 (region 11p1203→11p1208

ISSN:1424-8581    

DOI:10.1159/000130809

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Using somatic cell hybrids between TK-deficient mouse cells and white blood cells derived from a patient with a translocation of the region p21→pter of chromosome 17, we have assigned the gene for human GLO to region p21→pter of chromosome 6. Since the HLA region is only 10 cM distant from GLO, these results also confirm that the HLA region is located on the short arm of human chromosom

ISSN:1424-8581    

DOI:10.1159/000130810

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Chromosomes of the owl monkey, Aotus trivirgatus, with 2n = 54, 53, or 52, have been stained to show quinacrine (Q-) and Giemsa (G-) bands, and a karyotypic arrangement has been proposed based on lengths, centromeric index, and banding pattern. C-bands were present at the centromeric region of every chromosome and over the entire short arm of certain acrocentric chromosomes; 5-methylcytosine was concentrated in the same regions. Bright Q-bands at the telomeric ends of the short arms of some chromosomes probably represent a second type of repetitive DNA. Ag-staining showed that only the chromosomes bearing a secondary constriction are nucleolus organizer chromosomes.

ISSN:1424-8581    

DOI:10.1159/000130811

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1424-8581    

DOI:10.1159/000130812

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1424-8581    

DOI:10.1159/000130813

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1424-8581    

DOI:10.1159/000130814

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1424-8581    

DOI:10.1159/000130815

出版商:S. Karger AG    

年代:1977

数据来源: Karger