摘要:

SUMMARYThe potency of topical corticosteroids has been evaluated using a recently described test which measures both their vasoconstrictor and anti‐inflammatory activities. Betamethasone valerate, fluocinolone acetonide and triamcinolone acetonide creams were found to have practically the same potency. They were all superior to a combination of fluocortolone caproate and fluocortolone trimethylacetate cream. A remarkable difference was observed between the vasoconstrictor and the anti‐inflammatory activity of the latter preparation. The significance of this finding is discus

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06365.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SUMMARYThis study has demonstrated that a single application of a 2–5% solution of indomethacin will decrease the redness, warmth, and tenderness of sunburned skin for 24 h or longer. For this purpose indomethacin is much more effective than a highly active corticosteroid cream.Prostaglandins appear to be important mediators of ultraviolet erythema (Greaves, Sondergaard&McDonald‐Gibson, 1971; Mathur&Gandhi, 1972). We reported that prostaglandin inhibitors, indomethacin and aspirin, injected intradermally, delay and decrease ultraviolet erythema (Snyder&Eaglstein, 1973). In this study we have evaluated the effects of topically applied indomethacin and a corticosteroid on sunburn induced by a sunlamp or by natural sunli

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06366.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

SUMMARYTwenty men and one woman with porphyria cutanea tarda were treated with oral chloroquine, 125 mg twice weekly.In nineteen of the patients chloroquine was taken for 8–5 months on average before complete clinical and biochemical remission occurred. Initially, treatment led to a considerable increase in urinary uroporphyrin and a mild increase in serum transaminases, but no adverse clinical reactions were observed. As the mechanism of chloroquine action in porphyria cutanea tarda has not yet been clarified, special caution must be observed when it is used therapeuticall

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06367.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06368.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06369.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06370.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06371.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06372.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

摘要:

Book reviewed in this article:Neonatal Dermatology. L.M.SolomonAND N.B.Esterley. Volume IX in the series—Major Problems in Clinical Pediatrics. AlexanderJ.Schaffer(Ed.) (1973).Handbuch der Speziellen pathologischen Anatomie und Histologie. Vol.7.Weibliche Geschlechtsorgane. F.Uehlinger(Ed.) Part4.Vulva, Vagina, Uretra. G.Dallenbach‐Hellweg, B.Egloff, H.G.Hillemanns, J.Jaeger, G.F.Klostermann, H.Limburg, K.Staffeldt andP.Stoll(1972).Rheumatology, An Annual Review, Vol.4,Oculocutaneous Manifestations of Rheumatic Diseases. G.E.Ehrlich(Volume Ed.)(1973).Human Melanin. EugeneFollmann(19

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06373.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1974.tb06374.x

出版商:Blackwell Publishing Ltd    

年代:1974

数据来源: WILEY