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11. |
Dapsone as first line therapy for bullous pemphigoid |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 83-92
V.A. VENNING,
P.R. MILLARD,
F. WOJNAROWSKA,
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摘要:
SUMMARYIn an open study, a total of 18 patients with proven bullous pemphigoid (16 new patients and two in relapse) were treated with a trial of dapsone (17 patients) or sulphonimide (one patient). Overall, eight patients were controlled on one of these agents as the sole treatment (44%). Six patients had a partial, but inadequate response, while four did not respond. The responses to the sulpha drugs were generally rapid, i.e. within 2 weeks, and the maximum doses used in any patient were 100 mg/day dapsone and 1.5 g/day of sulphapyridine or sulphamethoxypyridazine. Significant side‐effects to dapsone occurred in six of the 17 patients. A trial of a sulphone or sulphonamide drug is warranted in bullous pemphigoid both as an initial treatment or in the treatment of relapse, particularly when there is a contraindication to the use of corticosteroids. Side‐effects are common and therapy needs to be closely monito
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07769.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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12. |
Vibratory angioedema: lesion induction, clinical features, laboratory and ultrastructural findings and response to therapy |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 93-99
FRANCES LAWLOR,
ANNE KOBZA BLACK,
A.S. BREATHNACH,
M.W. GREAVES,
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摘要:
SUMMARYWe report the investigation and treatment of a 28‐year‐old woman with the rare condition of non‐familial vibratory angiodema.Lesions were reproduced using a vibrator set at pre‐determined frequencies and amplitudes, applied for a fixed time period. There was no indication of the production of tolerance in the patient with repeated vibration, but terfenadine produced a good therapeutic response. There was no evidence of mast cell degranulation at the ultrastructural level. The patient also had mild delayed pressure urticaria and dermographism, thus demonstrating the clustering frequently found in the physical urt
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07770.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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13. |
Chronic leg ulceration with livedoid vasculitis, and response to oral ketanserin |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 101-105
M.H.A. RUSTIN,
C.B. BUNKER,
PAULINE M. DOWD,
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摘要:
SUMMARYWe report a patient with a 6‐year history of recalcitrant painful ulceration of both lower legs, diagnosed as being due to livedoid vasculitis. The lesions healed rapidly and remained healed on treatment with oral ketanseri
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07771.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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14. |
Acute acral pustulosis |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 107-111
T.J. HOFFMANN,
ANNE KETTLER,
SUZANNE BRUCE,
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摘要:
SUMMARYWe report a patient with a pustular eruption in an acral distibution that developed abruptly 4 days after a streptococcal pharyngitis. The histology showed an intraepidermal vesicle filled with neutrophils with an underlying lymphocytic vasculitis. Direct immunofluorescence demonstrated heavy deposition of C3within the vessel walls. In addition, circulating immune complexes were found.
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07772.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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15. |
Intra‐epidermal neutrophilic IgA dermatosis with colitis |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 113-119
S. WRIGHT,
T. PHILLIPS,
J. RYAN,
I.M. LEIGH,
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摘要:
SUMMARYWe report the association of an intra‐epidermal blistering disease of the skin with colitis. Both the skin and large bowel epithelium were infiltrated by neutrophils and eosinophils, and showed intra‐epithelial deposition of IgA in an intercellular pattern. The colitis and the blisters responded well to treatment with daps
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07773.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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16. |
Lymphocytic lymphoma and acquired C1esterase inhibitor deficiency |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 121-124
S.G.N. RICHARDSON,
C.W.F. CLARKE,
G.B. GASSON,
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摘要:
SUMMARYWe report a 59‐year‐old woman who had progressive symptoms of angioedema for 3 years, culminating in an attack of laryngeal stridor. C1esterase inhibitor deficiency was confirmed and treatment with tranexamic acid produced considerable clinical benefit and improvement in complement levels. Two years later she developed clinical evidence of lymphocytic lymphoma. Splenectomy resulted in rapid correction of complement abnormalites. The patient received 6 months of chemotherapy after surgery and remained asymptomatic with normal complement levels 4 years la
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07774.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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17. |
Proceedings of the 242nd Meeting of the Netherlands Society for Dermatology and Venereology, Nijmegen, 6 February 1988 |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 125-138
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ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07775.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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18. |
Great toe‐nail dystrophy |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 139-140
T.A.J. Dawson,
R. Baran,
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ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07776.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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19. |
Congenital epidermolytic hyperkeratosis associated with multiple malignancies |
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British Journal of Dermatology,
Volume 120,
Issue 1,
1989,
Page 141-144
J.M. Edwards,
M.A.C.S. Cooper,
S. Bannerjee,
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ISSN:0007-0963
DOI:10.1111/j.1365-2133.1989.tb07777.x
出版商:Blackwell Publishing Ltd
年代:1989
数据来源: WILEY
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