摘要:

SUMMARYThe ultrastructural changes in extragenital lichen sclerosus et atrophicus have been studied in four cases. The most pronounced changes are present in the dermis, where there are collagen degeneration and regeneration and increased amounts of elastin. The basal lamina shows holes, long gaps, and replication. Degenerate dermal material passes into the epidermis, which has increased numbers of Langerhans' cells and decreased numbers of melanocytes. These phenomena are discussed.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02968.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYA patient is described with gross intestinal protein loss occurring in association with a typical dermatitis herpetiformis enteropathy, in whom no other gastrointestinal abnormality was identified.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02969.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYSera from patients with bullous pemphigoid, pemphigus vulgaris and other bullous conditions have been tested for auto‐antibodies by the indirect immunofluorescence (IIF) method.Positive confirmation of the initial diagnosis was obtained in approximately 75% of both pemphigus and pemphigoid cases.It is suggested that the major source of error in the IIF test lies in the existence of ‘pemphigus‐like antibodies’; and clinically, in diagnosing some cases of dermatitis herpetiformis as pem

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02970.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYA Study of fifty‐six cases of polymorphic light eruption has shown that the action spectrum frequently lies in both the long ultraviolet wavelengths (320‐400 nm) and the short ultraviolet wavelengths below 320

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02971.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYThe construction and performance of equipment consisting of a 1600 W xenon arc light source and a grating monochromator are described. Its suitability for use in the investigation of the reaction of the skin to ultraviolet (UV) radiation and to visible light is discussed.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02972.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYVarious solvents were used to remove osmium‐reactive phospholipids and free fats from guinea‐pig back epidermis before post‐fixation in osmium. After extraction, the osmium stained material which remained was probably due to proteins with reactive amino acids. After brief fixation in glutaraldehyde, followed by immersion of the tissue in pyridine, a phospholipid solvent, followed by osmium post‐fixation, the unkeratinized epidermal cells were practically unstained. Removal of phospholipid from the keratohyalin granules revealed them as aggregates of smaller particles, probably the protein component. The thickened plasma membranes of the horny cells were darkly stained in osmium. Removal of material from the interiors of these cells left empty spaces between the meshwork of filaments, indicating absence of matrix keratin. The contrast between the darkly stained keratinized cell membranes and filaments, and unstained unkeratinized cells was marked after lipid ext

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02973.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYTwo methods for the replication of skin surface are described. The first is for the macroscopic estimation of hair follicles. The second, which produces replicas for the scanning electron microscope, utilizes Formvar and Thiokol Rubber as the impression material. The replica exhibits fine microscopic detail, and demonstrates sweat gland activity. The technique does not displace the well documented Sylflo method, but may prove to be a useful adjunct.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02974.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYHerpes zoster of the anogenital area is reported in six patients. The inability to urinate and to defaecate is a serious complication. This entity is well known in the urological but seemingly unreported in the dermatological literature. None of these patients had a recurrence of the herpes, nor did any have a known neoplasm.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02975.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYThree cases of advanced myxoedema are reported who presented with Eczéma craquel

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02976.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY

摘要:

SUMMARYForty patients with pustulosis palmaris et plantaris were treated with tetracycline 250 mg twice daily or with placebo, in a double‐blind trial. In twenty‐eight patients the lesions were confined to the palms and soles, whereas twelve had psoriatic lesions affecting other parts of the skin and/or nails. Radiological signs of focal infection were found in eighteen patients. In thirty‐five patients positive bacteriological culture from pustules was obtained, the most common strain beingStaphylococcus albus.Tetracycline proved superior to the placebo (P<0.001) in improving the lesions of PPP. It is discussed whether the effect of tetracycline is due to an antibacterial mech

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1973.tb02977.x

出版商:Blackwell Publishing Ltd    

年代:1973

数据来源: WILEY