1. |
SOME CLINICAL AND FUNDAMENTAL ASPECTS OF ERYTHROPOIETIC PROTOPORPHYRIA |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 323-328
D. SUURMOND,
J. STEVENINCK,
L. N. WENT,
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摘要:
Summary—The cutaneous manifestations observed in 17 patients with erythropoietic protoporphyria are briefly discussed.A fluorocyte concentration test has proved to be useful for screening protoporphyria families. An acceleratedin vitrophotohaemolysis could be demonstrated not only in blood from protoporphyria patients, but also in normal blood to which a protoporphyrin ester has been added. A number of reducing agents appeared to be more or less potent inhibitors of the protoporphyrin‐induced photohaemoly
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06827.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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2. |
FABRY'S DISEASE IN CHILDREN |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 329-332
W. P. GROOT,
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摘要:
Summary—The symptoms of angiokeratoma corporis diffusum of Anderson‐Fabry in 5 boys and 3 girls in one family and 4 young adult females in another family are described. The age of onset of symptoms and signs varies considerably. The importance of establishing the diagnosis in childhood is discus
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06828.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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3. |
ANAEMIA IN DERMATITIS HERPETIFORMIS |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 333-342
J. J. CREAM,
G. L. SCOTT,
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摘要:
Summary—Forty‐three patients being treated with dapsone for dermatitis herpetiformis were studied to determine the prevalence and mechanisms of anaemia in this condition. Anaemia was more common than in a comparable normal control group although it was usually mild. Most patients had evidence of drug‐induced haemolysis which was dose related and this was the most important cause for anaemia. Malabsorption did not seem to be a significant factor in the development of anaemia. The incidence of iron deficiency was no greater than in the controls, despite urinary iron loss. Five patients had low levels of serum B12, of whom 3 had pernicious anaemia. The incidence of low serum folate levels was less than that found by other workers although serial estimations revealed considerable fluctuations.The possibility that patients with dermatitis herpetiformis are more susceptible to the haemolytic effects of dapsone and the possible effects of dapsone on oxygen transport are disc
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06829.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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4. |
TONSURE TRICHOTILLOMNIA |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 343-350
KENNETH V. SANDERSON,
PATRICK HALL‐SMITH,
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摘要:
Summary—We describe 8 cases of trichotillomania in women in which the scalp exhibits a cropped appearance over the crown, extending to the frontal margin in some cases, but sparing the nape of the neck and lateral margins. The condition has persisted with no improvement for periods up to 17 years in one case.The hair on the affected area is mostly less than 3 cm. long and of normal texture. Many of the short hairs have a tapered hypopigmented tip and when groups of hairs are plucked only anagen roots are found. There is no microscopical abnormality of the hair shaft and no exclamation mark hairs have been extracted. The only explanation for the persistence of newly growing short anagen hairs is the continual plucking of all those exceeding 3 cm. length.All the patients but one repeatedly denied interfering with their hair, even after the significance of the changes in hair growth had been explained to them. In all the cases except one, psychiatric assessment showed a provocative social situation and personality traits likely to result in a disorder such as trichotillomania.The disorder has many features in common with idiopathic trichoclasia as described by Sabouraud and other French writers. It could be mistaken for a congenital hair dystrophy and we believe other cases have been shown as “diffuse alopecia areata”.The tonsural pattern may be determined by a higher threshold for pain in the centre of the scalp than at the ma
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06830.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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5. |
YERSINIA ENTEROCOLITICA: A NEW CAUSE OF ERYTHEMA NODOSUM |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 351-354
NIELS MYGIND,
HANS THULIN,
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摘要:
Summary—Three cases of erythema nodosum associated withYersinia enterocoliticainfection are reported. The differential diagnosis is discussed, and it is concluded that the erythema nodosum was probably a complication of the Yersinia infection. The diagnosis was supported by serological investigations. The reported cases occurred in the southern part of Sweden during the summer of 196
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06831.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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6. |
BEYTHRASMA IN A HOSPITAL FOR THE MENTALLY SUBNORMAL |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 355-360
DOROTHY A. SOMERVILLE,
R. H. SEVILLE,
R. C. CUNNINGHAM,
W. C. NOBLE,
J. A. SAVIN,
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摘要:
Summary—An investigation of the incidence of erythrasma amongst patients in a psychiatric hospital for the mentally subnormal is described. The axillae, groins and toewebs were examined and clinical erythrasma, showing characteristic coral‐red fluorescence under Wood's light, was found in 43% of the 874 patients examined. The incidence in the groins was 18%, in the axillae 4% and in the toewebs 30%. Fluorescence of other skin sites was also seen in a small proportion of the patients. Diphtheroids fluorescing on tissue culture medium No. 199 could be cultured from 35% of the fluorescent skin areas and from 25% of non‐fluorescing sites. The incidence of erythrasma increased with age but was unaffected by state of personal hygiene, although fewer of the patients with a reasonable level of cleanliness carried fluorescent diphtheroids on non‐fluorescen
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06832.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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7. |
PALMAR AND PLANTAR SEED KEEATOSES AND INTEENAL MALIGNANCY |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 361-363
E. L. RHODES,
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摘要:
Summary—In a survey of 500 patients over the age of 40 years attending the skin clinic, 62% were found to have “seed” keratoses on their palms or their soles. No statistically significant association was found between the presence of these keratoses and internal malignancy.The proportion of patients with keratoses was higher in those with basal cell epitheliomata but the excess was not statistically signif
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06833.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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8. |
HISTOENZYMOLOGICAL STUDY OF DERMAL VESSELS IN NORMAL AND PATHOLOGICAL SKIN |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 364-370
J. HÉWITT,
M. GUIGON,
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摘要:
Summary—Twenty specimens of normal skin, taken from 8 different areas and 61 specimens from patients suffering from psoriasis, scleroderma (sclerodactyly), angiomas, basal‐cell and squamous‐cell carcinomas were studied histochemically for 13 enzyme activities.Alkaline phosphatase (AP) and adenosine triphosphatases are mainly useful in revealing the vascular pattern of the dermis, ATP'ases showing activity in larger vessels than AP. On the other hand, some metabolic changes in the vascular wall may be indicated by variations in AP and ATP'ase activities.The various other enzyme activities deserve studying for their metabolic significance. While in normal skin vessels, dehydrogenases of the glycolytic pathway are the most active, in pathological conditions like psoriasis, and carcinomas, other activities appear stronger: G6P‐DH, aconitase an
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06834.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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9. |
THE EFFECTS OF A 2‐NAPHTHOL PEELING PASTE ON SEBACEOUS GLANDS REMOTE FROM ITS SITE OF APPLICATION |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 371-376
E. W. POWELL,
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摘要:
Summary—The sebum excretion rate and chemical composition of sebum from the foreheads of 4 young men with acne vulgaris were changed markedly when a 2‐naphthol paste was applied to other skin sites. The excretion rate, free fatty acid content and wax ester content fell but the triglyceride content increased. Recurrence of acne on stopping treatment was associated with an increase in wax ester content and a decrease in triglyceride content but little change in excretion rate and free fatty acid cont
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06835.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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10. |
EMISSIVE STEREOSCAN AND TRANSMISSION ELECTRON MICROSCOPE PROFILES OF THE STRATUM CORNEUM |
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British Journal of Dermatology,
Volume 82,
Issue 4,
1970,
Page 377-384
R. T. SIMS,
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摘要:
Summary—A study by conventional electron microscopy of the black lesions in the dermatosis of kwashiorkor revealed no structural changes that could be associated with the colour change. The appearance of the epidermis was similar to that of depigmented skin. Intercellular spaces about 800 A wide between cornified cells could not be reconciled with the barrier function of the stratum corneum but this property could reside in retaining flanges over the edges of the cells.Scrutiny of the superficial surface of intact sheets and the cut surface of sections of healthy stratum corneum by the emissive mode of the Cambridge Scientific Instrument Company's Stereoscan showed that the intercellular space between cornified cells must be occupied by some structural component not demonstrated by transmission electron microscop
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1970.tb06836.x
出版商:Blackwell Publishing Ltd
年代:1970
数据来源: WILEY
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