摘要:

SUMMARY.—The authors investigated derangements in delayed hypersensitivity in 2 cases of reticulum cell lymphoma (reticulosarcoma).A cytotoxic factor in the blood plasma of the patients destroyed lymphocytes cultured with phytohaemagglutinin (PHA). The factor proved to be cytotoxic both to the lymphocytes of patients and to those of healthy individuals.The plasma factor, when added in small amounts to the culture medium, stimulated lymphocytes of healthy individuals to blastic transformation; but, at higher concentration, its cytotoxic effect became manifest.A relation was found between the presence of the cytotoxic factor and the clinical state and delayed skin reactions to bacterial and fungal antigens and to allograft rejectio

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb07169.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARYA calorimetric study in a patient with a pachydermoperiostosis points to a peripheral (possibly mitochondriat) cause for abnormalities in heat production. An improvement in the patient's appearance was obtained by plastic surgery.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14102.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARYA case is described in which a nondescript inflammation under the epidermis, orificial mucosae and bowel started in infancy and led to extensive cutaneous atrophy with some sclerosis. Similar changes probably affected the absorptive surfaces of the bowel leading to intractable malabsorption and death.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14103.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—A significant increase of the mean IgA globulin value was noted in 105 patients with ordinary psoriasis whereas the mean IgG and IgM globulin levels remained normal. Thirty‐two of these patients received u.v. light therapy which resulted in resolution of the skin lesions. At this stage the IgA levels fell to the normal range. The possibility of the skin eruption influencing the IgA serum levels is discus

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb07171.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARYThe term sporadic ulcero‐osteolytic neuropathy is used to describe isolated cases with the triad of peripheral neuropathy of the legs, ulcers, and painless destruction of bones and joints of the feet. Seven such cases in male South African Bantu are presented, in whom the changes were confined to the feet. Common causes such as leprosy, tabes dorsalis and diabetic neuropathy were excluded. Although a single cause could seldom be blamed, chronic alcoholism, malnutrition, and local trauma appeared to contribute. The clinical picture differed somewhat from other reported cases of similar causation. Sural nerve biopsy demonstrated a nerve lesion other than lepros

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14104.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—The existence of “dispersers” of micro‐organisms in a skin hospital is described. There appeared to be no single factor, such as the diagnosis or the treatment received, which might be responsible, although all dispersers were amongst the most heavily colonized of patients. One strain of staphylococcus appeared to be selectively acquired by patients with mycosis fu

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb07173.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARYSix cases of livedo reticularis with ulceration were treated with large amounts of low molecular weight dextran. The lesions healed well with this therapy, and subsequent relapses have been less frequent and easier to control. The method of administration is outlined and a possible explanation for the prolonged beneficial effect is advanced.

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14105.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—The percutaneous absorption of 1‐naphthol‐[1‐14C] has been studied in 3 men. This compound was rapidly metabolized and excreted in the urine largely as 1‐naphthol conjugated with glucuronic acid; small quantities of radioactivity were present in the sulphate fraction. The results suggest that absorption was efficient; 65.0–23.8% of the applied dose could not be recovered from the skin. Large systemic doses could thus be administered through the skin. The relevance of the findings to an understanding of toxicity due to these compounds i

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb07174.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARYTwo main types of epidermolysis bullosa affecting the Bantu are described. The possible evolution of the albopapuloid variety as seen in 2 patients with the dominant dystrophic type is discussed. The presentation of an infant with localized absence of skin and subsequent epidermolysis bullosa letalis supports the hypothesis that epidermolysis bullosa letalis with congenital localized absence of skin represents an intra‐uterine phase of the diseas

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb14106.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY

摘要:

SUMMARY.—A simple, rapid and reproducible method for the semiquantitative determination of the main lipid classes of sebum is describe

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1971.tb07175.x

出版商:Blackwell Publishing Ltd    

年代:1971

数据来源: WILEY