摘要:

SUMMARY.—A review of the clinical features of 113 and the histological features of 42 patients with erythema perstans is presented. In none of the patients was a cause definitely established. Seven patients had an internal malignancy. In only 3 of the 7 was there a temporal relationship between the malignancy and the erythema perstans such that an aetioiogical relationship could be seriously considered. Six patients in a control group of 113 patients with psoriasis had an internal malignancy. Erythema perstans may sometimes be a sign of internal malignancy, but the present study indicates that this is true less often than previously suspecte

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16202.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—The history, technique, applications and complications of lymphangiography are described. The value of lymphangiography in dermatology has been assessed and confirmed in a series of patients suffering from malignant reticuloses, malignant tumours and benign disorders such as eczema and the yellow nail syndrome. Nine illustrative case reports are briefly described and the usefulness of lymphangiography in dermatology is discusse

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16203.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—A modified radiographic method for measuring skin thickness has been described; it has given consistent results. Normal values have been ascertained for adult males and females. It is suggested that this method will be of value in studying conditions in which changes in skin thickness are to be expecte

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16204.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—Eighteen cases of acquired fibrokeratoma are recorded and their histology described. There seems little justification for regarding them as “extrusions of normal dermis”, as has been suggested. They are possibly traumatic in o

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16205.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—This paper describes the evolution of subungual epidermoid inclusions and discusses their aetiology. They are shown to develop from the tips of the rete ridges by a process of bulbous proliferation. Ultimately they may lose their connection with the epidermis and come to lie deeply within the dermis of the nail bed. Although the lesions are usually microscopic in size they may be large and should be considered in the differential diagnosis of nail bed swellings.The aetiology of these lesions is still obscure. They may follow trauma and are found in finger clubbing and it is probable that different stimuli can produce the

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16206.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—Dyskeratosis is a feature of certain benign and malignant epithelial disorders. In Bowen's disease, dyskeratosis is characterized by central displacement, aggregation and condensation of tonofilaments within individual cells at all levels of the epidermis. This premature keratinization isprimaryand is similar to the benign dyskeratosis observed in keratosis follicularis. Centrally displaced dyskeratotic material was observed intermingled with the mitotic apparatus. Giant cells apparently resulted, since nuclear but not cytoplasmic division was seen. Dyskeratosis may also besecondary, through phagocytosis by one cell of partly or completely keratinized material from other cells. This may result in formation of a second distinct type of giant cel

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16207.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—Manganese levels in normal epidermis and dermis from 34 cadavers were estimated by neutron activation analysis. The mean concentration of manganese in the epidermis was 4 times higher than that in the dermis. An important biological role of manganese in skin is suggested by the remarkably narrow range of concentration of that trace metal in the analysed sample

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16208.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—Histochemical investigations on epidermis of adults and foetuses of different ages have demonstrated that there is a close relationship between histidine content and keratohyalin granules. Where the latter are absent the histidine level is low. Only after the development of the second active protein synthesizing layers of the epithelium does keratinization begin in embryonic lif

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16209.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—Antibody reacting at low titres with the basement membrane zone of jejunal mucosa was detected in the sera of eight patients with dermatitis herpetiformis, using an indirect immunofluorescent staining technique. Five of these sera reacted with normal jejunal mucosa, and with abnormal jejunal mucosa from patients with dermatitis herpetiformis. Three other sera reacted only with mucosa from dermatitis herpetiformis. Direct immunofluorescent staining revealed the presence of fixed γ‐globulin in the basement membrane zone of jejunal mucosa from 4 patients with dermatitis herpetifo

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16210.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY

摘要:

SUMMARY.—The method introduced by Strauss and Pochi (1961) for measuring the rate of sebum secretion has been critically investigated and a number of sources of error defined. These are choice and preparation of absorbing papers, the technique of sebum collection, weighing, and the ambient humidity. A decrease in the absorbency of the paper during the collection was not found. Modification of the method with careful attention to detail has increased the reproducibility of the results and there is good agreement of the results on both sides of the forehead and in collections made over a 7‐week period.The amount of sebum collected in the first 3‐hr, period was greater than in subsequent 3‐hr, periods but there was a direct linear relationship between the amounts collected in the first 3 hr. and subsequent 3‐hr, periods. The view that the method measures the sebum secretion rate is critically discussed in the light of this observation. It is suggested that the amount of sebum collected may be more directly related to the pool of sebum already secreted. Since the size of this pool is related to the rate of sebum secretion the method provides an indirect measure of this function. Until we know more precisely what we are measuring we prefer to use the descriptive term “rate of sebum

ISSN:0007-0963    

DOI:10.1111/j.1365-2133.1969.tb16211.x

出版商:Blackwell Publishing Ltd    

年代:1969

数据来源: WILEY