ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02847.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

ABSTRACTA randomized, double‐blind study was carried out in 300 consecutive coronary angiography examinations to investigate the clinical safety of three low osmolar contrast media, iohexol 300, ioxaglate 320 and iopamidol 300, and the electrocardiographic changes that occurred with them. The ECG from electrode V5/V6 or AVF and intra‐arterial pressure were monitored continuously, and recorded before and after the first contrast injections into the left and right coronary arteries. Of the variables tested, no statistically significant changes occurred in systolic arterial pressure, PR interval or ventricular extrasystole. The QT interval increased in the ioxaglate group (p=0.001). Heart rate decreased in all groups, but slightly less in the ioxaglate group than in the iopamidol group (p=0.02). The ST segment depression (mean 0.67m) was more marked in the ioxagiate group than in the other treatment groups (p=0.0001) during right coronary angiography. The same characteristics, but less marked, were observed during left coronary angiography, the ioxaglate group (mean 0.251mm) differing from the iopamidol group (mean 0.050mm) (p=0.04). No significant difference in severe adverse reactions were detected between these groups (ioxaglate 1, iopamidol 1). Ioxaglate produced mild side effects (nausea, vomitus, urticaria) in 16% of the patients, the other two contrast agents producing side effects in

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02848.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02849.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02850.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

ABSTRACTSeven patients with peripheral nerve sheath tumours affecting the lumbo‐sacral plexus were examined with MR imaging utilizing a 1.5T magnet and spin echo pulse sequences. The majority of tumours were homogeneous in signal intensity and isointense with adjacent muscle on T1weighted images and showed markedly increased signal intensity on T2weighted images with central areas of relatively low signal intensity.An attempt to obtain a pathological correlation with the areas of low signal on T2weighted images was unsuccessful.The use of Gadolinium DTPA in one patient resulted in irregular enhancement of both a neurogenic sarcoma and smaller neurofibromas.The multiplanar imaging capabilities, high soft tissue contrast, non‐invasiveness, lack of ionizing radiation and the characteristic appearance of neural tumours makes MR ideal for imaging these lesi

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02851.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

ABSTRACTSpecimen radiography is already established as an essential adjunct to excisional biopsy of mammographically detected abnormalities.Two methods of specimen sectioning following the initial specimen radiograph are described. The techniques were devised to identify the lesion accurately in the specimen for subsequent pathological analysis. They have been tailored to suit the differing facilities at two Breast Screening Centres.The methods highlight the desirability of a cooperative multidisciplinary approach to the management of breast disease. They underline the importance of radiological localization of the lesion; not only for the surgeon, but also for the pathologist.

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02852.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

ABSTRACTThe authors have reviewed 308 localisation biopsies performed on nonpalpable breast lesions between 1986 and 1990. The initiating mammogram, specimen radiograph, radiologists' reports and histology reports have been analysed with respect to the nature of the mammographic lesion, patient age, breast parenchymal pattern and histologic diagnosis.The overall malignant biopsy rate was 28%. Malignancy was found in 67% of biopsies for architectural distortion, 27% for calcification and 25% for a mass lesion. Masses if malignant proved to have an invasive component in the majority of cases (29/33). Calcification if malignant was more often in situ carcinoma (25/44).29% of malignant biopsies were in women under the age of 50 and approximately half of these had an invasive component. The histologic nature of benign lesions is presented with identification of those with proliferative breast disease.The results are compared with those of other recently published series. Implications are discussed for the management of minimally suspicious lesions and for screening mammography.

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02853.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

ABSTRACTOver a 42 month perid 133 patients underwent 148 CT guided biopsies of 104 pulmonary lesions (78%), 21 mediastinal/hilar masses (16%) and 8 pleural lesions (6%). There were 48 cases (32%) complicated by a pneumothorax, of which 13 (9%) required a chest drain. Two cases each of minor haemopneumothorax (1.4%) and haematoma (1.4%) were found, and haemoptysis occurred in a single patient (0.7%). This low complication rate reflects the use of the 22 gauge Chiba needle, the small number of passes undertaken at each sitting and the wide range of lesion size.In four cases no diagnosis was established either at the time of biopsy or subsequently. There were 100 cases proven to be malignant, of which 81 were diagnosed at the first biopsy. Three further cases were regarded as suspicious of malignancy. Of the 29 patients with benign disease, a specific diagnosis was made in 10 (34%) and nonspecific inflammation was seen in 17 (59%) further patients.Fine needle aspiration under CT control is a useful and accurate diagnostic technique. It has widened the scope of lesions which can be biopsied, enabling small, deep or necrotic parenehymal lesions to be targeted accurately. A precise placement of the needle tip into pleural or mediastinal lesions is a further advantage. However, if an inadequate sample is obtained, the biopsy may need to be repeated.

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02854.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

ABSTRACTModified Gianturco arterial stents were placed in the iliac arteries of 3 non‐atherogenic sheep. At three months after placement there was no evidence of migration of the stents or of excessive intimal overgrowth in relation to the stent

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02855.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0004-8461    

DOI:10.1111/j.1440-1673.1991.tb02856.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY