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| 21. |
Effects of liver ischemia on hepatic protein synthesis in vitro and in vivo |
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Acta Physiologica Scandinavica,
Volume 114,
Issue 1,
1982,
Page 143-148
PER‐OLOF HASSELGREN,
JÖRGEN FORNANDER,
RUDOLF JAGENBURG,
ELISABETH SUNDSTRÖM,
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摘要:
When an in vitro system is used to study the influence of ischemia on hepatic protein synthesis, an important question is whether alterations observed in vitro reflect changes in vivo. In the present study the effects of liver ischemia on protein synthesis were investigated in rats both in vitro and in vivo. Liver ischemia was induced by hepatic artery ligation. Protein synthesis in vitro was determined from leucine incorporation into proteins in liver slices incubated in a medium containing14C‐leucine (0.5 mmol/l) and in vivo from leucine incorporation into hepatic proteins after intraportal injection of a tracer dose of14C‐leucine. Leucine incorporation rate in non‐ischemic liver was 0.16 pmol * g pror1h‐1in vitro and 19.6 μmol g prot‐1. h‐1in vivo. After hepatic artery ligation protein synthesis in vitro was reduced by about 60% and in vivo by about 80%. Thus, the relative changes were of the same magnitude in vitro and in vivo. This indicates that an in vitro system can be used to evaluate the effects of liver ischemia on hepatic prote
ISSN:0001-6772
DOI:10.1111/j.1748-1716.1982.tb06963.x
出版商:Blackwell Publishing Ltd
年代:1982
数据来源: WILEY
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| 22. |
Glucose stimulated net uptake of Ca2+in the pancreatic β‐cell demonstrated with dual wavelength spectrophotometry |
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Acta Physiologica Scandinavica,
Volume 114,
Issue 1,
1982,
Page 149-151
ERIK GYLFE,
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ISSN:0001-6772
DOI:10.1111/j.1748-1716.1982.tb06964.x
出版商:Blackwell Publishing Ltd
年代:1982
数据来源: WILEY
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| 23. |
Neurotensin‐like immunoreactivity in the preganglionic sympathetic nerves and in the adrenal medulla of the cat |
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Acta Physiologica Scandinavica,
Volume 114,
Issue 1,
1982,
Page 153-155
J. M. LUNDBERG,
Å. RÖKAEUS,
T. HÖKFELT,
S. ROSELL,
M. BROWN,
M. GOLDSTEIN,
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ISSN:0001-6772
DOI:10.1111/j.1748-1716.1982.tb06965.x
出版商:Blackwell Publishing Ltd
年代:1982
数据来源: WILEY
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| 24. |
VIP‐induced cyclic AMP formation in the cat submandibular gland Potentiation by carbacholine |
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Acta Physiologica Scandinavica,
Volume 114,
Issue 1,
1982,
Page 157-159
BERTIL B. FREDHOLM,
JAN M. LUNDBERG,
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ISSN:0001-6772
DOI:10.1111/j.1748-1716.1982.tb06966.x
出版商:Blackwell Publishing Ltd
年代:1982
数据来源: WILEY
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