摘要:

Summary.Inulin and PAH clearances and extraction values for PAH have been used to study the function of itidiviclual kidneys in dogs. A technique is described for collecting urine without catheterizing the ureter. Percutaneous catheterization of the renal veins has been utilised to determine both unilateral and bilateral extraction values for PAH. No significant difference from normal values was produced by the operation of one ureter. The values were practically equal for both sides. Extraction of PAH was somewhat lower in dogs than in humans.Much of this work was carried out during the time Professor B. Carlström was head of the department of medicine, Veterinärhögskolan. We should like to thank him for the generous support and helpful advice he has given

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01612.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.The carbonic anhydrase inhibitor acetazolamide affects the production of aqueous humour in rabbits without changing the steady state osmotic pressure gradient between aqueous and plasma.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01613.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.1Taste solutions, distilled water, touch and thermal stimuli were applied to the tongue of monkey, cat, dog, rabbit and rat, and the effects on the impulse discharge in the glossopharyngeal nerve were recorded.2Salt‐, bitter‐ and acid taste was found in all the animals investigated.3Response to sweet‐tasting solutions was obtained in all these animals except the cat. Only the monkey did, however, respond to saccharine.4Water taste was found only in the monkey.5Effects to warm and cold were seen in all the animals investigated except in the rat where warm solutions gave no response.6A tactile response was found in all species.7The findings were compared with those previously obtained from the chorda tympani (Tab

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01614.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.1Direct stimulations of the carotid sinus nerve have been performed in man during operations of tumours in the neck. Definite reflex responses were obtained already at low stimulation rates, with maximal effects around 40–60 impulses per sec.2A reflex bradycardia and a blood pressure fall with a decreased pulse amplitude was obtained. Concomitantly there was a marked fall in resistance to blood flow within the forearm vascular bed.3The fall in pulse pressure is in all probability due to a decreased stroke volume, secondary to a reduced venous return when the capacity vessels are widened, and to an dimination of the positive inotropic effect on the heart, as a consequence of the generalized reflex inhibition of sympathetic tone.4Stimulation of the cranial sympathetic trunk gave no evidence of any activation of the carotid baroreceptors, secondary to increased intramural tension, as has been reported in some animal specie

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01615.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.1The differences in stimulation threshold of the preganglionic fibres to a number of functionally‐differentiated sympathetic neuro‐effectors have been studied.2The results indicate that the fibres to the cutaneous arterio‐venous anastomoses, to the nictitating membrane and the pupil have as an average the lowest threshold, and hence probably the largest fibre diameters. Another group is formed by the constrictor fibres to,e. g., the ordinary skin vessels, the muscle and the tongue vessels, while the sympathetic dilator fibres to the muscle vessels have by far the highest threshold, and therefore probably the smallest dia

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01616.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.1Allicin — a potent enzyme inhibitor prepared from garlic —was observed to block in low concentrations (2. 10‐6‐2 * 10‐4‐M) thein vitrodegranulation of rat mast cells produced by compound 48/80, by a histamine liberator prepared fromAscaris lumbricoides, by antigen‐antibody reaction, and by lecithinase A. Glutathione in excess reversed the blocked degranulating processes.2The observations were considered to support our theory that the degranulation of mast cells produced by those agents is due to activation of a lytic enzyme attached to the mast cell membrane.3This enzyme is— in common with lecithinase A — dependent on sulfhydryl groups

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01617.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.Catechol amine containing granules of the cow adrenal medulla were isolated and resuspended in solutions of varying ionic composition. Analyses of the intragranular fluid indicated that the granule membrane is permeable to sodium, potassium, sucrose, and catechol amines. It was concluded that the catechol amines occur in the granules in an osmotically inactive form, probably in combination with an equivalent amount of adenosine triphosphate.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01618.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.It is demonstrated experimentally that quadratic metrics apply in the component structures with intensity and surface area dimensions of the haptic type of perception.

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01619.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Zusammenfassung.Der Zusammenhang zwischen dem bei voluntärer Aktion eines Muskels erbrachten Kraftimpuls und der integrierten, elektrischen Aktivität im Elektromyogramm wurde untersucht. Die Versuchs‐ergebnisse zeigen, dass bei der nicht‐isometrischen Zeigefingerab‐duktion die integrierte, elektrische EMG‐Aktivität bei stärkeren Aktionen relativ schneller zuwachst als bei schwächeren.Summary.The relation between the mechanical impulse produced by a muscle in voluntary action and the integrated electric. activity in the electromyogram was investigated. The experimental results indicated that in non‐isometric abduction of the forefinger the integrated electric activity increased relatively more rapidly in connection with stronger than

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01620.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY

摘要:

Summary.1A photopic electroretinogram (ERG) with two negative and four positive humps was recorded earlier (heckand Rendahl1957). In the course of dark adaptation, an ERG has now been recorded which appears to contain one additional negative wave and one positive one, evidently the scotopic components.2It has been found possible to suppress the various components of the ERG successively by increasing the light adaptation.3On examination of six deuteranopes, an ordinary photopic ERG was obtained. On adaptation to green light, the fourth component was unaffected in two cases. A markedly decreased sensitivity to green light was observed in a similar way in three subjects with deuteranomaly (a fourth exhibited the same variations as in subjects with normal colour sense).4In the four other deuteranopes, the fourth component was suppressed on adaptation to green light, exactly as in normal eyes; the sensitivity to green light was perhaps increased.5On the basis of this and other investigations of colour blindness, the suggestion is put forward that the first type of deuter‐anopia is due to a lack of “green receptors” in the retina, whereas the second type is to be ascribed to the impulses from retinal receptors with different oolour sensitivity being coupled to the same nerve

ISSN:0001-6772    

DOI:10.1111/j.1748-1716.1958.tb01621.x

出版商:Blackwell Publishing Ltd    

年代:1958

数据来源: WILEY