ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01246.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

One hundred and twenty seven randomly selected Polish Jews were studied for their HLA polymorphism. Gene frequencies exceeding 0.1 were detected forA1, A2, Aw19, B14, Bw16andBw17.Significant gametic association was observed for (A1, Bw17), (A2, B27), (Aw26, Bw16), (Aw19, B13) and (A28, B14). Although a predominantly Caucasoid population, the Polish Jews show greater resemblance to Middle Eastern rather than to Northern European Caucasoids.

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01247.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

HLA typing of 123 Israeli Jews of Russian origin showed a high frequency for HLA—A1, A2, Aw19andB14, Bw16andBw35of the A and B loci, respectively. The most frequently occuring haplotypes were (A1, B17), (Aw25, B18), (Aw26, Bw16), (Aw19, B13), (Aw23, B5) and (Aw25, Bw35). This study reveals a striking resemblance in the distribution of frequencies of HLA alleles and haplotypes between Russian Jews and two other East European Jewish communities (presented in this issue) of Polish and Rumanian origi

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01248.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Seventy‐three random Jewish individuals whose families have lived in Germany for at least 4–5 generations, were typed forHLAantigens at the A and B loci.In comparison with other European populations, the frequencies ofB7andB12are low whereasBw35is almost twice as frequent (21%). Among the uncommon associations found in the German Jews were: (A2, Bw21), (Aw25, B18), (A29, B14), (A28, Bw15). The frequent haplotype (Aw24, Bw35) was previously found, but only in Asia and in American Indians.Subdivisions of the subjects according to geographic regionswithinGermany point to differences in gene frequency between the gro

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01249.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

The frequencies of 29 HLA antigens of the A and B loci were studied in 130 Israeli Jews originating from Rumania. The antigensA1, A2, Aw19andB14, Bw16andBw35occurred with the highest frequencies. The most common haplotypes were (A1, B17), (Aw26, Bw16) and (A28. Bw22), These results are similar to those observed in Polish and Russian Jews.

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01250.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

One hundred and forty one unrelated Moroccan Jews living in Israel were studied for their HLA polymorphism. Gene frequencies exceeding.1 were found forA1, A2, A3, Aw19, B5, B12, andB13.Significant linkage disequilibrium occurred for (A1, B8), (A2, B5), (A2, Bw21), (A3, Bw40), (A9, B7), (A10, Bw16), (A29, B15) and (Aw19, B14). They represent an intermediate population between Europe and the Middle East.

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01251.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Phenotype and gene frequencies of antigens at the A and BHLAloci were determined in a sample of 89 random Libyan Jews now settled in Israel. Most antigens at the A locus are within the range found in European populations while, at the B locus, the frequencies differ from Caucasoid populations:B7is usually rare (1%),Bw35is frequent (14%) andBw40very common with more than 10%.Thirteen percent of Libyan women whose sera were screened for the presence ofHLAantibodies gave positive results. Some of them are elderly women, about 15 years or more beyond their last birth.

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01252.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

One hundred and twenty three Iraqi Jews, now living in Israel, were studied for their HLA polymorphism. Gene frequencies exceeding. 1 were found forA1, A3, Aw19, B5, B12, andBw35. A28, B8andB14were relatively rare whereasAw25andBw37were not found at all. Significant gametic associations occurred for (Aw23, Bw21), (Aw26, Bw16), (A11, B5), (A28, B8) and (A28, B7). The Iraqi Jewish population was found to be typical of Asiatics and Middle Easterners.

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01253.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

Gene and phenotype frequencies for the threeHLAloci were determined for 90 random Armenians from the Old City of Jerusalem, Relatively high frequencies were found forHLA—A2, A3andAw24, while the lowest frequencies were those forAw23andAw25.The major distinguishing antigen, when compared with European Caucasoids isBw35with a frequency of 22%.Two unusual associations between the B and C loci were observed:Bw17, Cw3andB7, Cw3.Another interesting association in Armenians,Aw32 Cw4, has previously been found only among Cochini Jews and Malay population

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01254.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

HLA gene frequencies in 11 Israeli populations and nine other relevant populations were used to calculate genetic distances in a quantitative assessment of their similarities and differences.The shortest distance found is between Polish and Rumanian Jews, while the largest is between Russian Jews and Black Africans. Estimates of “average” distances within major population groups suggest that the Ashkenazi Jews (Poles, Russians, Rumanians and Germans) are a more homogeneous population than East European non‐Jews or than Middle‐Eastern populations (Arabs, Armenians, Lebanese and Turks).A cline of distances between Ashkenazi Jews and other Jewish communities parallels their geographic distribution; however, the relatively large distance between the two North African communities (Libyans and Moroccans) demonstrates that geographic proximity is not necessarily correlated with genetic similarity.The Jewish populations, especially the Ashkenazi, show a clear divergence from their neighboring non‐Jewish populations, among whom they have lived for many centuries.There are indications in theHLAdata of a common origin for the diverse Jewish po

ISSN:0001-2815    

DOI:10.1111/j.1399-0039.1978.tb01255.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY