摘要:

SummaryTwo cases are reported of Vietnamese men who presented in young adult life with recurrent, painful, erythematous patches (which we have termed “erythralgia”) over and adjacent to Joints and accompanied by marked constitutional symptoms of malaise and lethargy, arthralgia and in one patient, fever In the other, from the onset of the disease there were nodules over the bony prominences and in the interphalangeal regions of the fingers. The duration of the disease was over 12 years, the duration of each episode without therapy was one week and the interval between episodes was one to two weeks. In addition the patients showed a raised ESR and peripheral neutrophil leucocytosis of over 70%. There was a rapid response, within hours, to non‐steroidal anti‐inflammatory agents.Skin biopsies taken at varying stages of the disease episode failed to demonstrate neutrophils thereby failing to satisfy one major criterion of Sweet's Syndrome. Direct immunofluorescence studies were negative. Biopsy of the nodules did not show rheumatoid pathology. The serum rheumatoid factor was negative. Investigations failed to demonstrate any recognised pattern of cutaneous or rheumatologic disease; infections such as borreliosis were excluded. Both patients showed evidence of past hepatitis B infection.As recurrent painful cutaneous erythema is an uncommon phenomenon in dermatology except where the patient is suffering from recurrent cellulitis of the lower limbs, the patients reported here exhibit a pattern of disease not previously de

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00098.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

This review was presented as a paper at The Annual Meeting of the Australasian College of Dermatologists, Perth, May 1991.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00099.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryAlpha hydroxy acids (AHA's) or “fruit acids” are a special group of organic acids found in many natural foods. They have been described in the literature for the treatment of a number of conditions in which abnormal keratinization consistently contributes to pathogenesis. These include the icthyoses, warts, psoriasis, eczema and acne. We have performed a double‐blind clinical trial on 150 patients to evaluate the efficacy and skin tolerance of the alpha hydroxy acid gluconolactone 14% in solution (NuvodermTMlotion) in the treatment of mild to moderate acne when compared with its vehicle (placebo) and 5% benzoyl peroxide lotion. The results of this study showed that both gluconolactone and benzoyl peroxide had a significant effect in improving patients'acne by reducing the number of lesions (inflamed and non‐inflamed). Furthermore, fewer side‐effects were experienced by patients treated with gluconolactone when compared with benzoyl

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00100.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThe natural history of congenital inclusion dermoid cysts of the scalp is unknown. We report three cases of this condition, which has been followed from birth for up to ten years. Dermoids are congenital subcutaneous cysts, which gradually flatten and scar over a number of years. The lesions are covered with skin showing focal alopecia but they may be surrounded by a collar of hypertropic hair. Later in life flattened cysts may be mistaken for aplasia cutis, but the history of a cyst at birth allows the clinician to distinguish these two conditions. As these cysts have a potential for intracranial extension, this is an important clinical entity.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00101.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummarySubcutaneous fat necrosis of the newborn is an uncommon but distinctive condition which appears in the first six weeks of life, associated with variable degrees of hypercalcaemia and which resolves spontaneously over months. We report a case of subcutaneous fat necrosis of the newborn following perinatal distress and complicated by thrombocytopenia and hypercalcaemia.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00102.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryTea tree oil (an essential oil derived primarily from the Australian native Melaleuca alternifolia) has been used as a topical antiseptic agent since the early part of this century for a wide variety of skin infections; however, to date, the evidence for its efficacy in fungal infections is still largely anecdotal. One hundred and four patients completed a randomized, double‐blind trial to evaluate the efficacy of 10% w/w tea tree oil cream compared with 1% tolnaftate and placebo creams in the treatment of tinea pedia. Significantly more tolnaftate‐treated patients (85%) than tea tree oil (30%) and placebo‐treated patients (21%) showed conversion to negative culture at the end of therapy (p◂0.001); there was no statistically significant difference between tea tree oil and placebo groups. All three groups demonstrated improvement in clinical condition based on the four clinical parameters of scaling, inflammation, itching and burning. The tea tree oil group (24/37) and the tolnaftate group (19/33) showed significant improvement in clinical condition when compared to the placebo group (14/34; p = 0.022 and p = 0.018 respectively). Tea tree oil cream (10% w/w) appears to reduce the symptomatology of tinea pedis as effectively as tolnaftate 1% but is no more effective than placebo in achieving a mycological cure. This may be the basis for the popular use of tea tree oil in the treatment of tine

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00103.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

Book review in this article:Genetic Disorders of the Skin.Joseph C. Alper (Ed).

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00104.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryThe AIDS epidemic has become a world‐wide health problem since the disease was identified ten years ago. An HIV‐dermatology outpatient clinic was established at the Albion Street Centre in Sydney to manage patients with cutaneous manifestations of AIDS. This study reviews the spectrum of skin disorders seen, and attempts to correlate skin disease with the degree of immunosuppression as reflected by CD4 or T helper lymphocyte counts, whereas previous reports have attempted to correlate skin disease with clinical signs and symptoms. Brief summaries of HIV disease and the cutaneous manifestations of AIDS are gi

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00105.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00106.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

SummaryLinear scleroderma is an unusual form of localised scleroderma, mainly affecting the legs and occurring primarily in children. Sometimes the linear lesions may extend to involve the underlying muscles and bones, with severe disturbances in growth and possibly flexion deformities of the legs.1,2,3,4In this study, two cases suffering from linear scleroderma of the legs are presented.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1992.tb00107.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY