摘要:

SummaryOnycholysis and other nail changes are occasionally found in association with hypothyroidisin in adults, but no previous report has been found of nail changes as a presenting feature of primary acquired hypothyroidism n a child (who also has a unique combination of endocrinopathies and other disorders).

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00202.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00203.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryThe investigation of patients with suspected liver disease requires a logical approach to diagnostic decision making. Answers to the following questions are needed‐Is hepatobiliary disease present? What is the diagnosis? What is the prognosis? A sequential approach to investigation is advocated including a two step process for the elucidation of the diagnosis. The principles expounded are readily applied to new investigations and their current role is discusse

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00204.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00205.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryPatients with dermatitis herpetiformis, chronic prurigo of adults and bullous pemphigoid reported in this study have responded more effectively to their specific drug therapy if trace metal supplement were provided. A lesser dosage requirement or even final elimination of drugs like dapsone or corticosteroids, resulted. Most frequently, a zinc and magnesium mixture was prescribed, although zinc only or magnesium only mixture was given in some patients. The plasma zinc and plasma magnesium levels in these patients were frequently below normal or in the low normal range.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00206.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryPotent topical corticosteroids have been documented as causing Cushing's syndrome and hypothalamo‐pituitary‐adrenal suppression. This can be minimized by restriction of potent preparations to specialists and by using these compounds for a minimum, but effective period. If potent corticosteroids are used for prolonged periods, then hypothalamo‐pituitary suppression should be excluded or confirmed by a metyrapone

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00207.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryThis study was conducted with 16 subjects to determine whether the topical application of betamethasone dipropionate (Diprosone) 0.05% cream, in amounts of 30 or 60 g daily for a period of four weeks, would lead to adrenocortical suppression. Five patients were given 60 g daily, six patients given 30 g daily and five normal subjects 30 g daily. Adrenocortical function was assessed weekly by means of plasma cortisol levels. The results showed that transient adrenocortical suppression may follow the use of betamethasone dipropionate 0.05% cream daily at these dosage levels and this may be a function of heightened absorption in some individuals.It is intended to carry out a further trial using both plasma cortisol determination and insulin‐induced hypoglycaemia as a measure of hypothalamus‐pituitary‐adrenal axis suppression, as it is believed that minor and moderate degrees of adrenal suppression may not become obvious from plasma cortisol determina

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00208.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryTwo pigmented lesions (one on each cheek of an adolescent boy) have been examined histologically on two occasions at an interval of eighteen months. The lesions had appeared following exposure to strong sunlight. Epithelial thickening with increased pigmentation, perifollicular mucin, absence of sebaceous glands and increased elastic tissue were found. Some comments are offered to explain these changes. It appears that the lesions are of naevoid origin.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00209.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryThe reticular erythematous mucinosis syndrome of Steigleder is a macular erythema‐tous form of inflammatory mucinosis. Clinically and histopathologically it has many similarities with the plaque‐like mucinosis of Perry. Transitional forms between the two conditions exist. The histopathological picture of the syndromes is not diagnostic and is indistringuishable from that of the lymphocytic infiltration of the skin described by Jessner and Kanof and from some of the chronic inflammatory dermatoses. The clinical picture in combination with the histopathological changes is, however, sufficiently characteristic to define the mucinosis of Steigleder and Perry as a clinical ent

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00210.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryBiopsy specimens of 102 patients with mycetoma were examined histologically and Madurella mycetomii was found in 29 cases. Four cases of mycetoma pedis and a single case of mycetoma of the hand from which M. mycetomii has been isolated in culture are described. In all cases, the characteristic black granules were seen.The geographic distribution of the organism and its incidence and prevalence in India are discussed.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1978.tb00211.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY