摘要:

SummaryA 30‐year‐old woman with a complex 13‐year history of chronic active hepatitis developed pyoderma gangrenosum whilst on treatment with low dose prednisone and azathioprine. A histological picture of suppurative granulomatous inflammation on skin biopsy raised the possibility of an opportunistic infection and delayed the diagnosis and institution of appropriate therapy. The lesions failed to heal with skin grafting or clofazimine therapy. Increased doses of azathioprine had to be ceased because of toxicity. High dose corticosteroids induced healing although vertebral osteoporosis necessitated its rapid withd

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00737.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00738.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

SummaryNew cases of primary cutaneous melanoma occurring in Queensland in a recent twelve month period were ascertained from pathology records. The reported incidence rates have risen, even in a two and a half year period, from 32.7 in 1977 to 39.6 per 100,000 population in 1979–80. The main prognostic features are presented and confirm an increased proportion of thin tumours, particularly of the lentigo maligna melanoma type. To determine underlying medical and public awareness of melanoma a random sample of the total year's patients was interviewed to establish how the tumours were first noticed. This factor of awareness in an educated high‐risk community may affect the observed incidence patterns of malignant melanoma and should be considered when seeking to explain the reported rising tre

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00739.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

SummaryBindii dermatitis is seen in children in late spring and early summer. The rash involves the knees and often affects the soles, elbows, forearms and palms. It resolves in winter. Recognition is important as the rash has been confused with other conditions.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00740.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

SummaryA rare benign skin tumour with the histology of an epithelioid leiomyoma is described in an eight‐year‐old boy. Some comments on malignant varieties are mentio

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00741.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

SummaryImmunoelectron microscopical examination with peroxidase labelled anti‐human IgG of the lesional skin in discoid lupus erythematosus showed an abundance of extracellular organized finger‐print deposits (OD) in the papillary dermis, probably contributing to the lupus band seen in direct immunofluorescence test. The OD is probably an immunoglobulin but its assembly as seen in the ultra thin section does not resemble known arrangements of protein subunits. Its spatial arrangement may be due to a membrane‐like structure rather than a three‐dimensional tubular configuration. Fine granular densities found together with OD are either additional immune reactants or degraded OD. In the deeper dermis these deposits, probably in the process of degradation, were found within the secondary lysosomes of the dermal macrophages. The significance of OD in the diagnosis of lupus erythematosus needs further confi

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00742.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

SummaryIn this study, twenty patients with mild or moderately severe psoriasis were divided into two groups. In one group the combination of PUVA therapy and dithranol cream was compared with PUVA therapy alone. In the other group dithranol 0.2% in Lassar's paste was compared with dithranol cream. On an overall assessment, patients improved after treatment for a period of four weeks. In the group comparing dithranol cream with 0.2% dithranol in Lassar's paste, seven of the eight patients preferred dithranol cream. Both preparations caused staining of the skin and clothes but irritation of the normal skin was more prevalent in those areas treated with dithranol 0.2% in Lassar's paste. The dithranol cream formulation (Di‐Cream) was shown to be a stable, effective formulation that was more acceptable to patients than dithranol in Lassar's past

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00743.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00745.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Books reviews in this article:Hair Research. Status and Future Aspects. Edited by C. E. Orfanos, W. Montagna and G. Stuttgen.Basics of Dermatologic Surgery. By S. J. Stegman, T. A. Tromovitch and R. G. Glogau.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00746.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1982.tb00747.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY