ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01815.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

SUMMARYThe results of erythrocyte uroporphyrinogen decarboxylase estimations of members of the family of a child with porphyria cutanea tarda are reported.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01816.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

SUMMARYThe characteristics and results of treatment of 30 patients with subungual malignant melanoma treated at the Sydney Melanoma Unit were studied. It was found that in several major respects subungual melanoma differed from other forms of cutaneous melanoma. Patients with subungual melanoma were considerably older than those with either superficial spreading or nodular melanoma and there was a preponderance of men with subungual melanoma of the upper extremity. Independent prognostic factors (such as tumour thickness) which are important in determining survival in patients with superficial spreading or nodular melanoma, had little consequence in patients with subungual melanoma. Despite the fact that the vast majority of subungual melanomas were very thick and ulcerated due to the delay in correctly diagnosing the disease clinically, overall survival rate was reasonably good, providing patients had an amputation of the entire digit together with either a prophylactic or therapeutic lymph node dissection. These findings indicate that subungual melanoma is a disease entity separate from other forms of cutaneous melanoma and that radical surgery is essential in all subungual melanoma patients.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01817.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01818.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

SUMMARYMycobacterium ulcerans infection was first reported in patients from the Bairnsdale district in Victoria in 1937, although ulcers probably due to this organism have been described in Africa since the last century. Characteristically the disease occurs in patients resident in defined areas, and such areas have been identified in many countries throughout the world. In Victoria cases have occurred recently in patients living some distance from Bairnsdale, and there appears to have been some extension of the endemic area. At the same time cases have occurred in koalas, but there appears to be no direct transmission between the koala and human cases.The characteristic clinical features of the disease in humans are described and illustrated. In recent Victorian cases the incidence appears to be seasonal, cases appearing in late autumn and winter months. Skin testing with the test reagent Burulin may be of value when diagnostic histological or microbiological material is lacking.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01819.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01820.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01821.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

SUMMARYTrouser dermatitis presenting as a generalised erythroderma is an uncommon event. Such a case is described and patch tests suggested that there was a sensitivity to disperse dyes.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01822.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

SUMMARYThe chance of malignancy developing in a giant pigmented naevus is often regarded as sufficiently high to justify prophylactic removal of all giant pigmented naevi as soon as possible, but most of the reports from which these figures are derived appear biased because of selection of patients.Because malignant melanoma seemed extremely rare in the Australian prepubertal child, attempts were made to document its frequency. Despite difficulty in obtaining complete figures, sufficient information was obtained to confirm the extreme rarity of malignant melanoma in general and especially arising in a giant pigmented naevus before puberty. It is therefore suggested that there is no general indication for prophylactic removal of giant pigmented naevi in Australian prepubertal children. Indications for removal on cosmetic grounds are discussed. It is speculated whether these conclusions might apply in other countries.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01823.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

SUMMARYFour children have been seen with a white line across the nose due to leucoderma in a transverse nasal crease, both of which are due to the habit of pushing up the tip of the nose with the palm or fingers. The parents are usually worried about the cosmetic defect but often have not realised the relation between the habit and the white line, or had not registered that the child had the habit, so that recognition and reassurance depend on appreciation of the cause, which may not be suggested by the history.

ISSN:0004-8380    

DOI:10.1111/j.1440-0960.1985.tb01824.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY