摘要:

A resected case of chondromyxoid fibroma of the right fibula in a 31‐year‐old male is presented. The histology was composed of characteristic lobular features of this tumor with abundant cartilaginous matrix. The ultrastructural study exhibited stellate, ovoid or elongated tumor cells with features of cartilage cells and abundant loose matrix with many fine filamentous structures. The nuclei were often of peculiarly indented contour and revealed thick fibrous lamina. The villous cell processes and intracytoplasmic fine filaments were prominent. No cells suggesting a fibroblast were recognized in this study. From the light microscopical and ultrastructural findings of this case, it is supported that this tumor might be derived from adult cartilage cells most likely related to the epiphyseal cartilage rather than fibrobla

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02032.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Clinical and pathological findings are reported in a Japanese girl who died of secondary amyloidosis associated with juvenile rheumatoid arthritis two years after the onset of symptoms. The patient had intermittent high fever, rheumatoid rash, polyarthralgia, and hepatosplenomegaly. The joints showed the typical histologic changes of juvenile rheumatoid arthritis. Amyloid deposition was found in various tissues; however, remarkable deposition of amyloid was observed in the gastrointestinal tract, especially in the ileum. The amyloid protein in this patient was identified as protein AA using the methods of potassium permanganate treatment and the peroxidase‐antiperoxidase unlabeled antibody techniqu

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02033.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

An unusual case of a 37‐year‐old female with xanthomatous bone tumor of the right molar area of the mandible was presented. The tumor was asymptomatic and found to be a well‐demarcated intraosseous radiolucent lesion on radiographic examination. Histologically the tumor consisted of two cell types, fibroblastic and xanthomatous cells. There was no osteoid, bone or cartilage formation. However, numerous psammomatous calcified bodies were seen in the fibrous area. Ultrastructural study showed fibroblastic cells in different stages of proliferation as the basis of the tumor which transform itself into xanthomatous cells. From the clinicopathologic findings, our case was thought to be a xanthic variant of non‐ossifying fibroma (so‐called xanthofibroma) of the

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02034.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

A case of a chimpanzee with fulminant hepatitis caused by spontaneous hepatitis A virus (HAV) infection was reported. The liver at autopsy revealed massive liver cell necrosis with mononuclear and polymorphonuclear cell infiltration. Aggregation of HAV‐like particles (22–25 nm in diameter) were found within the vesicles of hepatocytes under the electron microscope. Immunofluorescent examination of the liver showed positive staining for HAV antigen, C1q, C3, C4, immunoglobulin M (IgM), and immunoglobulin G (IgG) in the hepatocytes and/or Kupffer cells in a granular fashion. The anti‐HAV antibody (IgM type) and circulating immune complexes were detected in the postmortem serum. The present study suggests the possibility that the deposition of immune complexes of HAV and anti‐HAV antibody in the liver cell plays an important role in the pathogenesis of massive liver cell necrosis in fulminant type A viral he

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02035.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

A case of bronchial plasmacytoma occurring in a 57‐ year‐old housewife is reported. She had had the productive cough and the “abnormal shadow” in the right lower lobe for three years before admission. On bronchocopy, a tumor was found in the right main bronchus, large enough to obstruct the air way. The tumor was resected through rigid bronchoscope. Histological impression was “plasmacytoma with local amyloid deposit.” M‐protein was never detected in the serum or urine. Applying the immunoperoxidase technique for the paraffin section, the plasma cells were found to contain only a single type of immunoglobulin, Ig G‐L. The differential diagnosis between plasmacytoma and plasma cell granuloma was made, and plasmacytoma was considered to be one type of extranodal mal

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02036.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Two cases of dirofilarial infection in the human being were reported. Dirofilarial infection is common in dogs but rather rare in human. A review of Japanese literature disclosed 13 cases of human dirofilarial infection. Scarcity of symptoms and its morphological similarity to tuberculosis or infarction as well as the popularity in pets suggest that the true incidence of infection may actually be higher than the above figure. Our cases alert us for the recognition of human dirofilarial infection, and careful examination of multiple sections in granulomatous or nonspecific infarcted lesions is suggested.

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02037.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

Presented here is an autopsy case of pachymeningitis cervicalis hypertrophica. A 77‐year‐old female had the initial symptoms of cervical radiculopathy which terminated in the syndrome of spinal cord transection. Prior to the onset of radiculopathy, the patient had been admitted to the hospital because of a fever and had been shown to have granulomatous sinusitis. Autopsy revealed chronic granulomatous pachymeningitis of the cervical spinal cord, the lesion being mostly restricted to this region. From histopathologic similarities, the extension of sinusitis to cervical pachymeningitis was assumed, but this was not confirmed. An attempt to discover the causative micro‐organisms was unsuccessful. The possibility of a limited form of Wegener's granulomatosis could be excluded in view of the absence of true angiitis. Corresponding to the levels of pachymeningitis, the spinal cord was also severely damaged, which was principally due to circulatory disturbance as a result of pachymenin

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02038.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

A female patient who died of apparent postirradiation sarcoma at the age of 39 was reported. Following a traffic accident, she developed squamous cell carcinoma at the injured right heel 20 years later, and also metastasis to both inguinal and popliteal lymph nodes. During the period from September 1966 to May 1968, she had received Co60irradiation to the right inguinal and para‐aortic areas, 9,600 and 6,600 Roentgen, respectively. Ten years later, she manifested a huge tumor in the inguinal region which extended further to the retroperitoneum; light and electron microscopic examinations proved to be a malignant fibrous histiocytoma. She died of massive pulmonary metastasis two years later. Histological differentiation of the tumor and relationship between irradiation and sarcoma induction were briefly discussed, and the necessity of reevalution of soft part sarcomas was emphasize

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1982.tb02039.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY