摘要:

Ten adult male rats, Wistar‐King strain, were injected in the foot pads with heat‐killed human type tubercle bacilli suspended in mineral oil. A high incidence of metastatic arthritis was noted in the other legs. Histological study of the primary focus and metastatic lesion was described. Acid‐fast stained sections revealed disseminated tubercle bacilli of intact form in the cutaneous lesion of the primary focus, lymph nodes of popliteal, inguinal, abdominal, para‐tracheal, axillary regions and the lungs. They were seen within adjuvant droplets. No bacilli were seen in the bone lesions, either of the injected limb or other legs. The dissemination of bacilli coated with oil droplets was suggestive that they were produced by spread through the lympatic channel. The pathogenesis of adjuvant arthritis was di

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01944.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01945.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

An autopsy case of a 20 year‐old female with lesion similar to those of lipoid nephrosis and given a large amount of steroid hormones was reported. The kidneys showed peculiar findings which were similar to those of diabetes mellitus and possibly modified by long‐standing use of steroids. In the present case, however, exudative lesions were prominent and nodular lesions were scanty in contrast with those of Kimmelsteil‐Wilson syn

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01946.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01947.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

Histological changes in the heart, especially on the formation of Aschoff body by prolonged sensitization with egg‐white for over one year were studied using 30 rabbits.Localized myolysis and acute angitis of various degrees were observed in the earlier period of the experiment. Localized or diffuse thickening of the media of coronary arteries was recognized in the later period. Aschoff bodies were demonstrated in 8 cases, taking place in the perivascular region of the myocardium, and they showed a more typical form in the later period as a result of altered immune response than these in the earlier period which is characterized by an allergic‐hyperergic condit

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01948.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

The human islets of Langerhans, obtained from a patient with gastric ulcer and from two autopsied diabetics, were examined by means of electron‐microscopy and histochemistry. Development of three kinds of secretion granules were followed and certain characteristics in their formation were described. Physiological presence of fat granules and other cytoplasmic inclusions were recognized. The beta cells from the diabetics revealed a definite decrease in ribosomes, Golgi apparatuses and secretory granules on one hand, and accumulation of fat granules as well as alpha and delta cells on the other. The hyalinous deposits in the islets of diabetics were elecron‐microscopically and histochemically consistent with amyl

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01949.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01950.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

1. In the cases of long‐term (over 10‐12 hours) artificial respiration, status bullosus of the cerebellar granule cell layer and faint staining of the nerve cells appear hand in hand. The latter change occurs predominantly in the brain stem (in the wider sense) and the cerebellar nuclei, and differs from the typical ischemic (hypoxic) brain change, not only in its distribution but also in its cellular degenerative pattern.2. Status bullosus became to be more frequently encountered in cases of meningioma, leukemia, and uremia as compared to previous years, and it appears mostly hand in hand with faint staining of the nerve cells.3. As the prerequisite of development of these changes, one must consider not only circulatory disturbance, but also metabolic disord

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01951.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01952.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1966.tb01953.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY