摘要:

SUMMARY1 We confirmed that the removal of parotid and submaxillary salivary glands (asialadenism) caused definite changes in many endocrine organs and definite degeneration of the cartilage tissue of bone and joint, dentin of teeth, elastic fiber system and other mesenchomal tissue.2 On the contrary, we confirmed that the removal of submaxillary salivary gland caused hypertrophy of the parotid gland (hypersialadenism) and contrary changes in endocrine organs to the aforementioned experiment, and also contrary changes in the same mesenchymal tissues.3 These changes in the deficiency of endocrine apparatus (secretory tube and glandular cells of salivary glands) are recovered by the administration of salivary hormone (Parotin‐Ogata).4 As the diseases which are caused by the deficiency of endocrine function of salivary gland we demonstrated the following three; chondrodystrophia fetalis, Kaschin‐Beck's disease, and arthropathia deformans.Chondrodystrophia fetalis seems to be caused by the retardation of development of endocrine function of salivary gland in the embryonic and new born stage.Kaschin‐Beck's disease, including the changes of bone in Aso volcanic disease, seems to be caused by the acquired deficiency of endocrine function of salivary gland in the growing stage.Arthritis deformans senilis seems to be caused by the disappearance of endocrine function of salivary gland in adult age.5 In diabetes mellitus, Graves' disease and myxoedema following sarcoma of the thyroid, we confirmed the definite secondary changes of the endocrine apparatus of salivary gland.6 In malnutrition we confirmed hyperplasia of the endocrine apparatus of salivary gland and pancreas, but with the complication of pneumonia and dysentery this endocrine apparatus is also degenerated.7 In rickets, which is refractory against vitamin D, we confirmed the disturbance of endocrine apparatus of salivary gland.8 We confirmed the close relationship between the disturbance of endocrine apparatus of salivary gland and the elasticomalacia of artery, i. e. arteriopathia senilis (Nordmann), but could not establish a direct relationship to the arteriosclerosis.9 In all our cases of arterial bleeding of the brain we confirmed degeneration of the endocrine apparatus of salivary gland as well as in the cases of emphysema.10 We are inclined to conclude that the endocrine function of salivary gland maintains the proliferation of mesenchymal tissues, i. e. cartilage, bone, teeth, elastic fiber, reticulo‐endothelial system, connective and hematopoetic tissues.11 These diseases, which seem to be primarily caused by the disturbance of endocrine function of salivary gland, are recovered by adequate substitutional ap

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1954.tb03314.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SUMMARYThe extensively widespread occurrence of the lesions caused by dead tubercle bacilli embedded in paraffin‐oil may be essential for the establishment of the state of hypersensitivity, even if such lesions may be an innocent tuberculoid change. And the fact that the lesions or metastatic foci are chiefly formed by invading the lymph channels, may probably play an important role in the mechanism of the occurrence of such innocent tuberculoid changes.Therefore, the tuberculo‐immunity premises the existence of tuberculous change; namely, it is exactly similar to that of typhoid fe

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1954.tb03315.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY

摘要:

SUMMARYA new fluorescence method for histochemical demonstration of phosphatase is presented by use of riboflavin‐5‐phosphoric ester as substrate. Consideration of mechanism of the yellow coloring in situ of the enzyme activity is described. Distribution of riboflavin‐nucleotidase in rabbit tissues is compared with nonspecific phosphatase and 5‐nucle

ISSN:1320-5463    

DOI:10.1111/j.1440-1827.1954.tb03316.x

出版商:Blackwell Publishing Ltd    

年代:1954

数据来源: WILEY