ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The spatial vectorcardiograms (sVCG) and electrocardiograms were studied with respect to the gross and microscopic data in 59 instances of myocardial infarction. Besides the early abnormalities in the QRS sÊ-loop frequently associated with the electrocardiographic Q of infarction, there were recognizable alterations in the sVCG associated with the anatomic location of the infarction: lateral wall infarcts shortened vectors in mid-QRS sÊ-loop, and posterior lateral basal infarction altered the terminal portion distinctively. The myocardial lesions included fresh infarcts, solid scars, scattered fibrosis, and scar with interwoven intact muscle fibers. Where many normal-appearing fibers were present in the lesion, the previously recorded ECG or sVCG frequently failed to show the diagnostic signs of infarction. However, by presenting the depolarization complex in greater detail, the sVCG supplemented the ECG, improving the accuracy of diagnosis of infarction, especially among the smaller, less solid lesions.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Serum phospholipid levels were determined in 1,067 healthy persons aged 2 to 77 years. Phospholipid levels increased with age but in a different way for each of the sexes. The age-sex changes of serum phospholipids were similar to those observed for serum cholesterol. Correlation coefficients in members of 156 families indicated that the genetic factor is of importance in determining the serum phospholipid level in health. Because of the age-sex variations of serum phospholipid and serum cholesterol levels, no single arbitrary line can be drawn between normal and abnormally elevated levels of these 2 serum lipid fractions.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Clinical experience suggests that there are differences in the extent to which hypertensive patients respond with falls in blood pressure after administration of effective doses of ganglionic-blocking drugs. In this study attempts are made to define the relative magnitudes of the postural and nonpostural falls in blood pressure that are produced by these drugs. Frequent measurements of the blood pressure were made in hypertensive human subjects before and after the administration of ganglion-blocking agents. Drug-induced falls in blood pressure are calculated with reference to the baseline levels of blood pressure established in various ways for the individual patients.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Seventy cases of pre-excitation were studied by vector translating methods. Certain properties of the delta event are described that are useful in the recognition of this syndrome electrocardiographically. In about half the cases a ventricular conduction defect without QRS-interval prolongation was demonstrated to have accompanied the pre-excitation. The type of ventricular conduction defect produced depended upon the particular direction of spread of the pre-excitation wave. This and other findings are incompatible with the hypothesis that pre-excitation is due to accelerated atrioventricular conduction and favor the hypothesis that it is due to bridges, whether morphologic or electronic, between atria and ventricles.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Following cessation of therapy for acute rheumatic fever manifestations of rheumatic activity frequently reappear. The incidence of these manifestations and their severity were studied during the 3-week observational period in 257 patients treated as part of the Cooperative Clinical Trial on the treatment of rheumatic fever. From the analysis of these manifestations certain concepts may be derived concerning diagnostic and therapeutic criteria.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The misconception that nonpenetrating trauma to the heart is relatively rare, is primarily due to the fact that myocardial contusion or traumatic pericardial lesions are usually well tolerated and the clinical findings transient and often difficult to recognize. However, the sequelae of this type of cardiac trauma may be serious. Therefore, a careful evaluation of every traumatized individual for cardiovascular injury is essential if the more serious complications are to be recognized and treated effectively. The most commonly encountered cardiac lesion at necropsy was myocardial rupture of a septum or a chamber wall. Now that surgical therapy is available for certain types of cardiac rupture, early diagnosis is essential. Thrombosis of a major coronary artery as a direct result of nonpenetrating trauma was not found in this study and is considered rare. Nevertheless, a previously diseased heart appears to be more vulnerable to trauma. Under these circumstances, it is often difficult to assess properly the extent to which trauma may aggravate a pre-existent disease.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Other substances, in addition to the heparin clearing factor, exert a plasma-clearing effect under experimental conditions. A mucin compound extracted from the pig gastric mucosa has recently been included among such substances. Its clearing effect, as evaluated by variations in plasma optical density, is as constant and evident as that of heparin, both in normal and atherosclerotic subjects under basal conditions. The resemblance in function between gastric mucin and heparin is accompanied by similarities in molecular structure between the 2 compounds. Gastric mucin may belong among the factors that under physiologic conditions regulate the transport and some phases of the intermediary metabolism of lipids.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The hyperlipemia induced by a fat meal in anginal patients is frequently associated with clinical and electrocardiographic changes suggesting transient coronary insufficiency. Gastric mucin administered to 10 anginal patients at the same time as a fat meal invariably prevented the hyperlipemia, evaluated as increase of plasma optical density, and in one half of the cases it reduced the magnitude of the electrocardiographic changes as compared with the changes found in control experiments. Gastric mucin therefore exerts a powerful antilipemic and clearing action. Its inhibitory effect on the electrocardiographic changes associated with alimentary hyperlipemia is less evident than that of heparin.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

A patient who had had trauma to the right shoulder and upper chest complained of a right supraclavicular mass. Examination revealed a cystic tumor made larger by performance of the Valsalva maneuver. Angiocardiography demonstrated that there was partial stenosis of the terminal end of the right innominate vein. This and the Valsalva maneuver were responsible for the filling of a right persistent jugular lymph sac that simulated a cervical tumor.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID