ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

摘要:

Anatomic, clinical, hemodynamic, and roentgenographic findings in six patients with congenital communication of a coronary artery with a cardiac chamber or the pulmonary trunk are presented. The literature is reviewed.A coronary artery may communicate anomalously, with any of the cardiac chambers, more commonly with those on the right side. In the six cases presented, the right coronary artery communicated with the right atrium in one case and with the right ventricle in another. The left coronary artery communicated with the right atrium and right ventricle in one case each, and with the pulmonary trunk in two cases.The most striking feature observed clinically was a continuous murmur. If a continous murmur is localized in an area atypical for patent ductus arteriosus, the diagnosis should be suspected. Conventional roentgenographic and electrocardiographic studies yielded no specific diagnostic features. The results of cardiac catheterization may reveal a left-to-right shunt, but they are diagnostically useful only when correlated with clinical findings.The only precise method of demonstrating the abnormality is by means of selective aortography performed by injecting medium into the very origin of the aorta.Cure is possible by surgical interruption of the fistulous tract.

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

摘要:

This study of 68 normal children has shown that in the supine position and under conditions of normal respiration splitting of the second sound averages .02 second in expiration and .04 second in inspiration. Inspiratory increase in splitting of the second sound is the result not only of a delay in pulmonic valve closure but also of earlier aortic closure. Movement of the aortic component is responsible, on the average, for 35 per cent of the difference in splitting of the second sound in inspiration and expiration.

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

摘要:

Dilatation of the pulmonary vessels of the upper zones and constriction of the vessels of the lower zones characterizes left ventricular decompensation.These changes may precede the onset of clinical symptoms providing a useful warning sign of impending danger.A hypothesis is suggested to account for the non-uniform vessel pattern.An exception is noted in patients with severe emphysema or bronchitis in whom generalized dilatation may occur.

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

摘要:

Prolonged overhydration and hyponatremia have been produced in 10 patients with use of Pitressin Tannate in Oil. Balance studies have shown that in patients who developed moderate hyponatremia, the drop in serum sodium could be explained by water retention. In patients who developed severe water intoxication, the very low levels of serum sodium (100-114 mEq./L.) could not be entirely accounted for by changes in salt and water balance.Certain patients failed to develop severe water intoxication although an equivalent degree of overhydration was achieved. In these subjects, further overhydration was limited by intermittent episodes of low solute diuresis. This diuretic escape from Pitressin effect has been evaluated by measurement of U/P osmolar ratio on 24-hour urine specimens as well as TcH2O during hypertonic mannitol infusion. Defects in both aspects of renal concentration were observed, although they were not necessarily coexistent.

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

摘要:

The fatty acid patterns of the serum chylomicrons of 10 normal and 10 hyperlipemic subjects were determined by gas-liquid chromatography, before and after feedings of cream, corn oil, and coconut oil. Their depot fat composition was analyzed. Changes in the composition of the fasting serum chylomicrons of these hyperlipemic patients after they were stabilized on low fat, and rice and fruit diets were also studied.Upon a full American diet, after 12 hours of fasting, the fatty acid pattern of the very light serum chylomicrons of the hyperlipemic patients was found to reflect that of the ingested fats, consisting chiefly of a mixture of saturated animal fats. The effect of food fats was less evident in the heavier serum chylomicrons and very low density lipoprotein fraction of these patients, where the pattern of endogenously synthesized fat predominated.A low-fat diet in eight of these patients caused a significant lowering of the serum chylomicron (triglyceride) concentration and a shift of chromatographic pattern of the very light serum chylomicrons toward that of the non-hyperlipemic subjects. It is apparent that the clearing of the exogenous fats from the serum permits the endogenous lipids to dominate the picture.A low caloric rice and fruit diet appeared to arouse a temporary acceleration in the mobilization of fat from the body depot in two patients. In these patients, the fatty acid composition of serum chylomicrons, the very low density lipoproteins, and the depot fat were found to be similar to one another.Dietary fat contributed directly to alimentary lipemia of the normal and diseased subjects. At or near the peak of alimentary lipemia, the composition of the very light serum chylomicrons of all subjects was found to be practically identical with the ingested fat. Alimentary lipemia of hyperlipemic patients was intensified and prolonged.A relative increase in oleic acid, together with an elevated oleic/stearic ratio has been reported in the serum chylomicrons of patients with coronary artery disease. The same findings occurred in our patients, when there was an increase (relative or absolute) in the very light serum chylomicrons, due either to excessive dietary fat intake or to increased mobilization of fat from the depot.

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID

ISSN:0009-7322    

出版商:OVID    

年代:1961

数据来源: OVID