ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Urinary catechol amines have been shown to be increased in a few cases of acute myocardial infarction. The present study shows that patients with acute myocardial infarction and with angina pectoris (after exercise) have an increase in plasma catechol amines as compared to normal subjects before and after exercise and as compared to patients with noncardiac types of pain. The significance of these findings is discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Only 5 reports of cases of renal arteriovenous fistula appeared before or in 1953. Subsequently, 7 isolated reports brought the total to 12, and the 3 that we are reporting make 15.In reviewing the subject, the classification, incidence, causation, clinical features, diagnostic procedures, and pathophysiologic features were considered. Good evidence supports the thesis that in cases of congenital arteriovenous fistula an eroding renal arterial aneurysm is etiologic.Outstanding clinical features were hypertension (to group 4) and myocardial insufficiency; these contrast markedly with features of the usual peripheral arteriovenous fistula. Dramatic relief of heart failure and lowered reserve followed corrective operation in every case in which these features were recorded; relief of hypertension followed corrective operation in 11 of 12 cases in which this feature was mentioned. A loud, diffuse, continuous bruit invariably was present.Preoperative and postoperative catheterization and indicator-dilution studies, angiograms and aortograms are diagnostic measures emphasized in our 3 cases. Arterialization of blood in the vena cava, greatly increased cardiac output, and markedly shortened recirculation times of the dye were found. Excretory urograms were abnormal in 11 of the 12 cases in which they were made.The mechanism producing hypertension appears related to loss of pressure, decrease in flow, and loss of pulsatile character in the renal artery distal to the fistula, giving a Goldblatt-kidney type of end result. A vicious cycle of increasing hypertension followed by increasing flow through the shunt makes heart failure inevitable.Since 10 of the 15 cases were reported in the last 4 years, indicating that the lesion is commoner than previously supposed, we advise auscultation over the renal regions in patients with cardiac enlargement or failure of unknown causation, unexplained deformities in urograms, and renal tumors.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Severe iron deficiency anemia is a common sequel to the heavy hookworm infestations prevalent in Uganda, and in some hypoxia can be so severe that heart failure supervenes. The clinical manifestations in 15 cases are described. Comment is made on reversible electrocardiographic changes.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

In view of the current interest in the possible relationship between elevated serum lipid levels, increased coagulability of the blood (or decreased blood fibrinolysis) and ischemic heart disease, the clotting and fibrinolytic activity of the blood were studied before and after a fatty meal in 9 patients with idiopathic hyperlipemia, 10 patients with primary hypercholesteremia, and 10 normal subjects. Six patients had evidence of coronary heart disease. The methods of study included procedures designed to assess the over-all coagulability of the blood as well as the measurement of specific clotting factors. Blood fibrinolytic activity was measured by both direct and indirect methods. Serum lipid studies were performed simultaneously.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Various abnormalities in metabolism of water and electrolytes have been noted in patients with arterial hypertension and have variously been considered as causes or results of the hypertension. In this paper new data on these relationships are presented by a study of the changes in renal function produced by intravenous hydration, Pitressin, and lowering of the blood pressure.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Nitroglycerin has been used extensively as a coronary vasodilator. Its remarkable clinical effect has been presumed to be related to a direct action on the smooth muscle of the coronary arteriole. No observations have been made of nitroglycerin action on the coronary circulation in man. This report presents studies of changes induced by the drug in 10 normal or nearly normal subjects. The authors present evidence that although coronary vasodilatation does indeed occur, it appears to be secondary to changes in myocardial oxygen requirements. Hemodynamic observations revealed a general decrease in pressures in both peripheral and pulmonary circuits; caution is urged concerning the occasional severe hypotensive effects of nitroglycerin.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Except for the electrocardiogram objective evaluation of the functional state of the coronary circulation in man is often difficult. The nature of the coronary circulation in the presence of known coronary insufficiency has not been evaluated. In this report, 17 patients were studied of whom 14 had angina pectoris. Observations were made of coronary blood flow and hemodynamics both at rest and following administration of nitroglycerin. The authors conclude thatrestingcoronary flow is normal, butcannot increasefurther with dilators. They consider this phenomenon a consequence of prior exhaustion of the dilator capacity of the arterioles in compensation for the atherosclerotic obstruction of the coronary tree. The "fixed flow" concept is suggested as an objective means of detecting coronary insufficiency. Nitrites probably relieve pain in some manner other than general coronary dilatation.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID

摘要:

Electrocardiograms of healthy men both native and long-term residents at 14,900 feet above sea level have been obtained and classified according to their dominant pattern. Most of the tracings showed signs of either right ventricular hypertrophy or right bundle-branch block, incomplete and complete. Some of the mechanisms responsible for these electrocardiographic changes found at high altitudes, such as pulmonary hypertension, positional changes of the heart, and chronic hypoxia, are discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1959

数据来源: OVID