摘要:

The transport of cholesterol and other lipids of serum is almost wholly in the form of very large molecular complexes of these lipids with variable amounts of protein. The exact components present in the blood of a particular individual may be quantitatively described both as to character and concentration by ultracentrifugal flotation of these components in the analytic ultracentrifuge. With this technic it is possible to demonstrate the presence of certain lipid and lipoprotein components which are related to coronary atherosclerosis, to hypertension and to other diseases associated with atherosclerosis, such as diabetes mellitus, the nephrotic syndrome and hypothyroidism. The blood level of these components may be influenced by dietary means. The blood level of these components is poorly correlated with the analytic serum cholestrol determined by the Schoenheimer-Sperry method.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

By blocking sympathogenic vasoconstrictor mechanisms with dibenamine, a dog's tolerance to severe hemorrhagic hypotension states is definitely improved. New evidence is presented that partial release from vasoconstriction achieved by, giving small doses of dibenamine during the impending shock state seems to provide animals with even greater tolerance to this standardized form of stress. Although the use of dibenamine clinically for this purpose seems contraindicated, the dangers of at administering vasoconstrictor drugs to patients in impending shock are emphasized.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

Ballistocardiograms were taken before and at intervals after mild exercise. The normal response has been ascertained by a statistical study of results obtained on 40 healthy subjects. The response of patients varies widely; in some the change after exercise is much diminished, but in others the response is abnormally increased. In some the form of the ballistocardiogram, normal at rest, becomes abnormal after exercise, so the exercise test will often bring out abnormalities not detected by observations made at rest. Additional evidence was secured that the ballistocardiogram may become abnormal before the clinical picture of coronary heart disease develops.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

Several electrokymographs were subjected to study of their recording fidelity. Distortions were found in respect totimeandamplitudeof recorded response. The recording defects were analyzed quantitatively, and the degree to which the various components of the electrokymograph contribute to these distortions was measured. The significance of these deviations in recording fidelity is discussed in reference to the application of the electrokymograph to the study of cardiovascular dynamics.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

Serum cholesterol (free, esters and total) and serum phospholipids were determined in 97 men who had experienced coronary heart disease prior to the age of 40, 146 healthy nonhospitalized men of comparable age and a group of 97 men who were "matched" to the coronary disease group. The mean values for serum cholesterol (total) were 286 mg. per 100 cc., 224 mg. per 100 cc., and 247 mg. per 100 cc. for the coronary disease group, control group and matched control group, respectively. The serum phospholipids were highest in the coronary disease group. It is demonstrated that the interrelationships of the lipids in coronary heart disease are more important than any one of the constituents taken by itself. The theoretic implications of the total cholesterol: phospholipids ratio are considered.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The effects of intravenous injections of aminophylline on the coronary blood flow, cardiac oxygen consumption, cardiac work, and cardiac rate were studied by catheterization of the right ventricle and coronary sinus in anesthetized dogs. There was no substantial increase in coronary flow when cardiac activity increased following injection of the drug; this suggested that the oxygenation of the myocardium in general was not improved. Further studies on coronary blood-oxygen saturations substantiated this concept as pertaining to the infarcted heart of dogs as well as the normal. Nitroglycerin however increased general myocardial oxygenation in normal hearts.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

This study concerns an evaluation of the anatomicopathologic changes found in blood vessels of the skin in areas of venous insufficiency in the lower legs. These changes have been compared with the vascular structure in comparable areas of skin in normal persons. Apparently evidence of arteriolar damage is more a concomitant finding in the clinical picture of chronic venous insufficiency than are venular changes. This is demonstrated in a study of 30 patients. The vascular changes show no correlation with the condition of the skin at the site from which the biopsy material was taken.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The rat myocardium was injured by means of a hot probe applied to the exposed surface of the left ventricle and the sequence of electrocardiographic changes was studied. Administered potassium as potassium chloride aggravated the electrocardiographic changes, while the administration of DCA improved the cardiographic picture. It is suggested that the beneficial action of DCA may be due to its plasma potassium lowering effect.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The endocardial surface of the right ventricle in four dogs was stimulated by a unipolar electrode introduced into the cavity of the right ventricle by means of a catheter. Electrical changes at a suprajacent point on the right wall were recorded by the V lead method of Wilson. In every experiment the induced QRS complexes were initiated by a positive electrical change.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

This paper summarizes the incidence of various arrhythmias in an unselected series of cardiac catheterizations and presents evidence for their reflex origin in some instances. The hazards are discussed and comments made about prophylaxis and treatment.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID